Transdisciplinary Training In Cardiovascular Research

心血管研究的跨学科培训

• 批准号: 10270065
• 负责人: J Kevin Donahue
• 金额: $ 53.35万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10270065
• 关键词: Cardiovascular system; Research; Training

ABSTRACT We propose the 1st competitive renewal of our transdisciplinary cardiovascular sciences training program (CVT32) at the University of Massachusetts Medical School (UMMS). We will continue to encompass the full spectrum of cardiovascular (CV) research from basic to population health. This breadth is part of the UMMS culture of conducting science that makes a difference. The CVT32 is a collaboration between the Division of Cardiovascular Medicine in the Department of Medicine and the Department of Population and Quantitative Health Sciences (PQHS) and involves 48 participating faculty from multiple departments. Our two MPIs have different research expertise, with one (Freedman) more in the bench through phase 1 clinical trials arena and the other (Kiefe) in the phase 2/3 clinical trials (efficacy) through effectiveness, implementation, and population-sciences arena. Trainees will have mentoring teams with a lead mentor in their CV area of interest and a co-mentor plus an additional mentor-in-training representing very different areas of research. The synergism of our CVT32 faculty spanning the entire spectrum is a unique strength of our CVT32 enabling us to train scientists in a transdisciplinary way, with bidirectional hypothesis generation. Team mentoring and hands-on research experience through the entire training period are key components of our CVT32, together with structured coursework and abundant enrichment activities tailored to the individual trainee. We have a doctoral program and a Masters of Science of Clinical investigation housed in PQHS, where all CVT32 trainees will each have their own cubicle, in close physical proximity to researchers across the spectrum. Building on the success of our 1st funding period, we propose to enlarge the program by attaining a steady-state of 4 postdoctoral trainees and 4 predoctoral trainees at a time, with terms of 2-3 years; and newly adding a 12-week summer research training experiences for 8 medical students/year enrolled in a 4-year clinical and translational research pathway. Thus, our aims are to 1) Expand our successful CVT32 across basic, clinical, and population health sciences geared towards translating research into effective clinical practice and policy, and generating new questions spanning the entire spectrum of CV research. 2) Recruit pre-and post- doctoral trainees forming a diverse group regarding sociodemographics, clinical background, and disciplinary perspectives. 3) Provide trainees with the individual mentoring, academic training, and technical skills that will ensure their success as independent investigators as well as contributors to team science. 4) Provide “hands on” research experiences within transdisciplinary teams that build on the strengths of the current environment of linkages between UMMS Departments, Centers, and Institutes.

摘要 我们建议我们的跨学科心血管科学培训的第一次竞争性更新 项目（CVT 32）在马萨诸塞州医学院（UMMS）。我们将继续 涵盖从基础到人群健康的心血管（CV）研究的全方位。这种广度 是UMMS文化的一部分，进行科学，使一个差异。CVT 32是一款 内科心血管内科和内科之间的关系 人口和定量健康科学（PQHS），涉及48名参与教师从多个 部门 我们的两个MPI有不同的研究专长，其中一个（弗里德曼）在板凳上通过 1期临床试验竞技场和其他（Kiefe）在2/3期临床试验（疗效）通过 有效性、执行和人口科学竞技场。学员将有指导小组 在他们感兴趣的简历领域有一位首席导师，一位共同导师加上一位额外的培训导师 代表了不同的研究领域我们的CVT 32教师的协同作用跨越整个 光谱是我们CVT 32的独特优势，使我们能够以跨学科的方式培养科学家， 双向假设生成。团队指导和实践研究经验， 整个培训期是我们的CVT 32的关键组成部分，与结构化的课程一起， 为学员量身定制的丰富活动。我们有一个博士课程和一个 PQHS中的临床研究科学硕士，所有CVT 32学员将分别拥有 他们自己的小隔间，与各个领域的研究人员都非常接近。 在我们第一个资助期成功的基础上，我们建议通过实现 稳态，每次4名博士后和4名博士前研究生，任期2-3年; 每年新增8名医学生12周的暑期研究培训体验 参加了为期4年的临床和转化研究途径。 因此，我们的目标是：1）将我们成功的CVT 32扩展到基础、临床和人群健康领域 致力于将研究转化为有效的临床实践和政策的科学， 涵盖简历研究整个领域的新问题。2)招收博士前、博士后研究生 形成一个关于社会人口统计学，临床背景和学科的多样化群体 视角3)为学员提供个人指导、学术培训和技术技能 这将确保他们作为独立的调查人员以及团队科学的贡献者取得成功。四、 在跨学科团队中提供“动手”研究经验，这些团队建立在以下优势之上： UMMS部门，中心和研究所之间的联系的当前环境。