NCTN - Network Lead Academic Participating Site: USC

NCTN - 网络领导学术参与站点:USC

基本信息

  • 批准号:
    10579243
  • 负责人:
  • 金额:
    $ 38.19万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2014
  • 资助国家:
    美国
  • 起止时间:
    2014-04-17 至 2025-02-28
  • 项目状态:
    未结题

项目摘要

ABSTRACT The USC Norris Comprehensive Cancer Center first participated in the research activities of SWOG in 1987 and was initially funded in 1992. This five-year grant cycle has had increased administrative and academic participation, with maintenance of high clinical and correlative trial entry, commensurate with available SWOG funding and added resources from USC. The major emphases of the USC team are (a) to provide leadership across the NTCN to design and efficiently perform clinical trials evaluating the safety and efficacy of novel regimens or modifications of existing regimens; (b) to provide leadership in biomarker development and in integration of new technologies into NCTN trials, taking advantage of a systematic approach to collection, processing, and storage of blood, normal tissue, fresh or frozen tumor tissue, and other relevant biologic samples for molecular and pharmacologic studies; and (c) to evaluate cancer treatment regimens in special patient populations, such as rare cancers, the elderly and ethnic minorities. USC investigators have not only contributed extensively to SWOG trials but have demonstrated administrative/academic leadership, facilitating the translation of specific themes of investigation to SWOG. Recent NCTN trials such as SWOG/ALLIANCE 80405 and S1401 characterizing metastatic colorectal and prostate cancer has significant increased the understanding of molecular subtyping and characterization of both cancers integrating cutting edge technologies including NGS testing and single cell molecular classification. USC UG1 members are playing an active role in NCI task forces and steering committees. As part of its dedication to cancer clinical research, USC has been successful in mentoring young investigators through the UM1 Career Development Awards, Project Team Memberships and SWOG Young Investigator Awards. USC has expanded its institutional training and mentoring capabilities. Lastly, as a Network Lead Academic Participating Site, USC will continue to bring unique strengths to the NCI National Clinical Trials Network thanks to its strength in recruitment of minorities to clinical trials, accrual to rare cancers such as biliary and bladder cancers, and a well- developed clinical research infrastructure.
摘要 南加州大学诺里斯综合癌症中心首先参与了 SWOG于1987年成立,最初于1992年获得资助。这一五年的赠款周期增加了 行政和学术参与,维持高临床和相关试验 入围,与SWOG可用的资金和南加州大学增加的资源相称。少校 南加州大学团队的重点是:(A)在整个NTCN中提供领导,以设计和 有效地进行临床试验,评估新方案的安全性和有效性 修改现有疗法;(B)在生物标记物开发和 将新技术融入NCTN试验,利用系统化的方法 采集、处理和储存血液、正常组织、新鲜或冷冻的肿瘤组织和其他 用于分子和药理学研究的相关生物样本;以及(C)评估癌症 特殊患者群体的治疗方案,如罕见癌症、老年人和少数民族 少数族裔。南加州大学的调查人员不仅对SWOG的试验做出了广泛的贡献,而且 表现出行政/学术领导能力,促进具体主题的翻译 对SWOG的调查。最近的NCTN试验,如SWOG/联盟80405和S1401 转移性结直肠癌和前列腺癌的特征显著增加了 对两种肿瘤分子亚型和特征的认识 EDGE技术包括NGS测试和单细胞分子分类。USC UG1 成员在NCI特别工作组和指导委员会中发挥积极作用。作为ITS的一部分 南加州大学致力于癌症临床研究,成功地指导了年轻的研究人员 通过UM1职业发展奖、项目团队成员和SWOG Young 调查员奖。南加州大学扩大了其机构培训和指导能力。 最后,作为网络领先的学术参与网站,南加州大学将继续带来独一无二的 NCI国家临床试验网络的优势得益于其在招募 少数人参加临床试验,患上罕见的癌症,如胆道癌和膀胱癌,以及一口井- 发展临床研究基础设施。

项目成果

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Vinay Duddalwar其他文献

Vinay Duddalwar的其他文献

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{{ truncateString('Vinay Duddalwar', 18)}}的其他基金

Integrated radiomic and liquid biopsy monitoring in SWOG S1802: A phase 3 therapeutic trial for metastatic prostate cancer
SWOG S1802 中的综合放射组学和液体活检监测:转移性前列腺癌的 3 期治疗试验
  • 批准号:
    10348199
  • 财政年份:
    2021
  • 资助金额:
    $ 38.19万
  • 项目类别:
Integrated radiomic and liquid biopsy monitoring in SWOG S1802: A phase 3 therapeutic trial for metastatic prostate cancer
SWOG S1802 中的综合放射组学和液体活检监测:转移性前列腺癌的 3 期治疗试验
  • 批准号:
    10154662
  • 财政年份:
    2021
  • 资助金额:
    $ 38.19万
  • 项目类别:
Integrated radiomic and liquid biopsy monitoring in SWOG S1802: A phase 3 therapeutic trial for metastatic prostate cancer
SWOG S1802 中的综合放射组学和液体活检监测:转移性前列腺癌的 3 期治疗试验
  • 批准号:
    10549381
  • 财政年份:
    2021
  • 资助金额:
    $ 38.19万
  • 项目类别:
NCTN - Network Lead Academic Participating Site: USC
NCTN - 网络领导学术参与站点:USC
  • 批准号:
    10361414
  • 财政年份:
    2014
  • 资助金额:
    $ 38.19万
  • 项目类别:

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