Minority Stress Reactivity and Hazardous Drinking

少数人的应激反应和危险饮酒

基本信息

  • 批准号:
    10242689
  • 负责人:
  • 金额:
    $ 16.93万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2017
  • 资助国家:
    美国
  • 起止时间:
    2017-08-01 至 2022-09-30
  • 项目状态:
    已结题

项目摘要

PROJECT SUMMARY/ABSTRACT Disparities in hazardous drinking and alcohol use disorder (AUD) have been documented across several disadvantaged groups (e.g., racial/ethnic and sexual minorities). Hazardous drinking and its consequences are a major public health priority and concern given their significant economic, mortality, and morbidity burdens. Stigma and discrimination-related stressors (i.e., minority stressors) contribute to our understanding of health disparities among these groups. Given the importance of minority stressors in predicting hazardous drinking, the research aims of this Mentored Clinical Scientist Research Career Development Award (K08) are to conduct a rigorous, innovative, and multi-method examination of minority stress and its effects on drinking in the lab and the natural environment among one disadvantaged health disparities group. Sexual minority (SM; i.e., lesbian, gay, or bisexual) adults are at increased risk for hazardous drinking compared to heterosexuals. SMs experience minority stressors, which range from daily and momentary slights to more acute forms of stigma, and are directly correlated with hazardous drinking. However, major limitations of the extant SM literature include the lack of objective measures of reactivity to minority stressors (i.e., biological markers), overreliance on cross-sectional data, and failure to account for individual differences in appraisals of minority stress or the contributions of minority stress on hazardous drinking beyond individual differences in daily general stress and lifetime cumulative stress. In addition, little is known about mediating mechanisms between minority stress and hazardous drinking. Consistent with Institute of Medicine and NIH’s call to expand the scientific knowledge base on factors contributing to SMs’ elevated rates of drinking, the research aims of this K08 are to: 1) examine the effects of psychophysiological mechanisms underpinning appraised minority stress and alcohol craving in a lab experiment of 70 SMs who are at most risk for developing AUD (i.e., heavy drinkers); and 2) use experience sampling methods (i.e., EMA) over a 30-day period, to examine: a) the effects of psychophysiological stress reactivity from the lab on minority stress reactivity and drinking in the natural environment and b) the prospective effects of minority stress on proximal changes in affect and drinking and its consequences in real time. While conducting this research and participating in several training and mentorship activities, the K08 candidate will develop new expertise in: 1) experimental laboratory research; 2) psychophysiological stress research and salivary research methodology; 3) experience sampling field methods (i.e., EMA); and 4) advanced statistical approaches for analyzing intensive longitudinal EMA quantitative data and physiological salivary laboratory data. This proposed project builds upon the candidate’s past work examining the associations between minority stressors and health outcomes among sexual and racial/ethnic minorities. Completion of this K08 award will provide the candidate necessary skills to be an independent researcher capable of advancing our knowledge of stress-specific factors predicting hazardous drinking.
项目总结/摘要 危险饮酒和酒精使用障碍(AUD)的差异已在几个国家得到记录。 弱势群体(例如,种族/族裔和性少数群体)。危险饮酒及其后果 鉴于其重大的经济、死亡率和发病率负担,这是一个主要的公共卫生优先事项和关切事项。 与耻辱和歧视有关的压力因素(即,少数压力源)有助于我们对健康的理解 这些群体之间的差距。考虑到少数民族压力源在预测危险饮酒方面的重要性, 该指导临床科学家研究职业发展奖(K 08)的研究目标是 对少数民族的压力及其对饮酒的影响进行严格,创新和多方法的检查, 实验室和自然环境中的一个弱势健康差距组。性少数(SM; 也就是说,女同性恋者、男同性恋者或双性恋者)成年人与异性恋者相比,危险饮酒的风险增加。 SM经历少数压力源,其范围从日常和瞬间的轻视到更严重的形式, 这是一种耻辱,并与危险饮酒直接相关。然而,现存SM的主要局限性 文献包括缺乏对少数紧张性刺激的反应性的客观测量(即,生物标记物), 过度依赖横截面数据,以及未能考虑到少数民族评估中的个体差异 压力或少数民族压力对危险饮酒的贡献超出了日常生活中的个体差异 一般应力和寿命累积应力。此外,对细胞间的介导机制知之甚少。 少数民族压力和危险饮酒。与医学研究所和NIH的呼吁一致, 科学知识的基础上的因素,造成短信'饮酒率上升,这项研究的目的是 K 08的目的是:1)检查评估少数民族压力的心理生理机制的影响 和酒精渴望在实验室实验中的70个SM谁是最有风险的发展AUD(即,重 饮酒者);和2)使用经验抽样方法(即,EMA)在30天的时间内,检查:a) 心理生理压力反应的实验室少数民族的压力反应和饮酒的自然 环境和B)少数民族压力对情感和饮酒及其 真实的后果。在进行这项研究并参加几次培训和指导的同时, 活动,K 08候选人将开发新的专业知识:1)实验室研究; 2) 心理生理应激研究和唾液研究方法; 3)经验抽样现场方法 (i.e., EMA); 4)分析密集纵向EMA定量数据的先进统计方法 和生理唾液实验室数据。这个项目是建立在候选人过去的工作 研究少数民族压力源与性别和种族/民族健康结果之间的关联 少数群体完成这一K 08奖将提供候选人必要的技能是一个独立的 研究人员能够推进我们的知识的压力特定因素预测危险饮酒。

项目成果

期刊论文数量(8)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Addressing Research Gaps in Sexual and Gender Minority Adolescents' Substance Use and Misuse.
解决性和性别少数青少年药物使用和滥用方面的研究差距。
Negative Attitudes and Beliefs Toward the #MeToo Movement on Twitter.
  • DOI:
    10.1177/08862605211001470
  • 发表时间:
    2022-08
  • 期刊:
  • 影响因子:
    2.5
  • 作者:
    Nutbeam, Meena;Mereish, Ethan H.
  • 通讯作者:
    Mereish, Ethan H.
Associations between anti-bisexual minority stress and body esteem and emotional eating among bi+ individuals: The protective role of individual- and community-level factors.
  • DOI:
    10.1016/j.eatbeh.2021.101575
  • 发表时间:
    2021-12
  • 期刊:
  • 影响因子:
    2.8
  • 作者:
    Jhe GB;Mereish EH;Gordon AR;Woulfe JM;Katz-Wise SL
  • 通讯作者:
    Katz-Wise SL
Sexual orientation disparities in mental health and substance use among Black American young people in the USA: effects of cyber and bias-based victimisation.
美国黑人年轻人心理健康和药物使用方面的性取向差异:网络和偏见受害的影响。
  • DOI:
    10.1080/13691058.2018.1532113
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Mereish,EthanH;Sheskier,Mikela;Hawthorne,DavidJ;Goldbach,JeremyT
  • 通讯作者:
    Goldbach,JeremyT
Heterosexist Bullying Victimization and Perpetration and Substance Use Among Heterosexual Adolescents.
异性恋青少年中的异性恋欺凌受害和犯罪以及药物使用。
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Ethan H. Mereish其他文献

Internalized Heterosexism and Psychological Distress: The Moderating Effects of Decentering
内在的异性恋主义和心理困扰:去中心化的调节作用
  • DOI:
    10.1037/sah0000065
  • 发表时间:
    2016
  • 期刊:
  • 影响因子:
    3
  • 作者:
    Jae A. Puckett;Ethan H. Mereish;H. Levitt;S. Horne;S. Hayes
  • 通讯作者:
    S. Hayes
(Dis)similarity Between Liberals and Conservatives: Predicting Variability in Group Differences on Abortion and Same-Sex Marriage Rights Attitudes
自由派和保守派之间的(不同)相似性:预测堕胎和同性婚姻权利态度上的群体差异的变异性
  • DOI:
  • 发表时间:
    2012
  • 期刊:
  • 影响因子:
    0
  • 作者:
    V. Poteat;Ethan H. Mereish
  • 通讯作者:
    Ethan H. Mereish
Mental Health and Care Utilization Among Sexual and Gender Minority Youth by Race and Ethnicity
按种族和族裔划分的性与性别少数族裔青年的心理健康与护理利用情况
  • DOI:
    10.1016/j.jadohealth.2024.11.244
  • 发表时间:
    2025-04-01
  • 期刊:
  • 影响因子:
    4.500
  • 作者:
    Hyemin Lee;Jessica R. Abramson;Arushee Bhoja;Ryan J. Watson;Ethan H. Mereish
  • 通讯作者:
    Ethan H. Mereish
Can friendships be bipartisan? The effects of political ideology on peer relationships
友谊可以是两党的吗?
  • DOI:
  • 发表时间:
    2011
  • 期刊:
  • 影响因子:
    0
  • 作者:
    V. Poteat;Ethan H. Mereish;Marcia L. Liu;J. Nam
  • 通讯作者:
    J. Nam
Mapping "Race"
绘制“种族”地图
  • DOI:
    10.36019/9780813561387
  • 发表时间:
    2013
  • 期刊:
  • 影响因子:
    5.4
  • 作者:
    R. Valdez;L. E. Gómez;Nancy López;J. Kahn;Joseph L. Graves Jr.;Jay S. Kaufman;John A. García;Simon J. Craddock Lee;Gabriel R. Sánchez;Vickie D. Ybarra;Derek Kenji Iwamoto;Mai M. Kindaichi;Matthew Miller;Aliya Saperstein;Janet E. Helms;Ethan H. Mereish;A. Geronimus
  • 通讯作者:
    A. Geronimus

Ethan H. Mereish的其他文献

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{{ truncateString('Ethan H. Mereish', 18)}}的其他基金

Long-term and Daily Associations among Intersectional Minority Stress, Structural Oppression, and Alcohol Use and Misuse among Sexual Minority Adolescents of Color
有色人种性少数青少年中交叉少数压力、结构性压迫以及酒精使用和滥用之间的长期和日常关联
  • 批准号:
    10664245
  • 财政年份:
    2022
  • 资助金额:
    $ 16.93万
  • 项目类别:
Long-term and Daily Associations among Intersectional Minority Stress, Structural Oppression, and Alcohol Use and Misuse among Sexual Minority Adolescents of Color
有色人种性少数青少年中交叉少数压力、结构性压迫以及酒精使用和滥用之间的长期和日常关联
  • 批准号:
    10620266
  • 财政年份:
    2022
  • 资助金额:
    $ 16.93万
  • 项目类别:
Minority Stress Reactivity and Hazardous Drinking
少数人的应激反应和危险饮酒
  • 批准号:
    9755274
  • 财政年份:
    2017
  • 资助金额:
    $ 16.93万
  • 项目类别:
Suicidal and Nonsuicidal Self-Injurious Behavior in Sexual Minority Youth: Examining Modifiable Mechanisms for Treatment Development
性少数青少年的自杀和非自杀自残行为:检查治疗发展的可修改机制
  • 批准号:
    9295331
  • 财政年份:
    2017
  • 资助金额:
    $ 16.93万
  • 项目类别:

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