Adhesion G Protein-Coupled Receptors in CNS Development and Regeneration

CNS 发育和再生中的粘附 G 蛋白偶联受体

• 批准号: 10622163
• 负责人: Xianhua Piao
• 金额: $ 5.67万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10622163
• 关键词: ADGR1 gene; Action Potentials; Adhesions; Axon; Cell Lineage; Cerebral Palsy; Coculture Techniques; Cognitive; Cre lox recombination system; Data Set; Deposition; Development; Disease; F-Actin; Failure; G-Protein-Coupled Receptors; Genes; Human; In Vitro; Incidence; Injury; Life; Light; Membrane; Microfilaments; Modeling; Molecular; Motor; Multiple Sclerosis; Mus; Myelin; Myelin Sheath; Natural regeneration; Nervous System Physiology; Neuraxis; Oligodendroglia; Pathogenesis; Pathologic; Pathology; Pathway interactions; Pattern; Perinatal; Pharmacology; Pregnancy; Premature Birth; Proliferating; Reporter; Research; Role; Sensory; Signal Transduction; Testing; Time; Transgenic Mice; Transgenic Organisms; Visualization; Zebrafish; career; design; in vivo; injury and repair; loss of function mutation; myelination; nervous system development; neuropathology; new therapeutic target; oligodendrocyte lineage; oligodendrocyte precursor; precursor cell; response to injury; single-cell RNA sequencing; small molecule; success; therapeutic target; white matter; white matter injury

PROJECT SUMMARY/ABSTRACT Please see Research and Career Plan.

项目摘要/摘要 请参阅研究和职业规划。