Genetics and Genomics Training Grant

遗传学和基因组学培训补助金

基本信息

批准号：
10623232
负责人：
ALLISON E ASHLEY-KOCH
金额：
$ 53.05万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-01 至 2025-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10623232
关键词：
Genetic Genomics Grant Training

项目摘要

The University Program in Genetics and Genomics (UPGG) has a nearly 40-year history of training graduate students at Duke University. The program has maintained its status over the years as an elite graduate training program by co-evolving with changes in experimental and analytical technologies, scientific culture, career development, and student demographics. Currently, the UPGG is a degree- granting program of approximately 50 students and 90 faculty with appointments in departments across the School of Medicine, School of Engineering, and Arts & Sciences. UPGG students have the opportunity to train in a broad range of fundamental research questions including chromosomes, nucleic acids, and gene expression; developmental genetics, population and evolutionary genetics; model systems genetics, human and mammalian genetics, plant genetics; and microbial and viral genetics. Our faculty train students in experimental and quantitative/analytical approaches across a variety of biological systems from microbes to plants to humans. This intellectual diversity, coupled with Duke’s highly collaborative culture, has created a truly interdisciplinary training environment. Our UPGG alumni populate a breadth of career paths from traditional academic research and teaching to industrial/government research or regulatory affairs, and small startup companies to big pharma. Our current trainees come from a variety of scientific, cultural, and socioeconomic backgrounds. This diverse population participates actively in their own training by organizing some of our signature programs, such as the annual student retreat, distinguished lecture series, and community outreach efforts. Additional programmatic offerings such as our Tuesday Seminar Series serve as a focal point for bringing together the entire Genetics and Genomics community together at Duke. In the coming grant period, we seek to leverage the current strengths and successes of the UPGG along with developing new programmatic and curricular offerings that support the intellectual and career development of our trainees. Our objective is to utilize the backdrop of genetics and genomics research at Duke to produce independent scientists who are well trained in the fundamental technical, leadership, and operational skills necessary for them to thrive in a range of scientific career paths. As part of our focus on student training, we will develop mechanisms for improving the mentoring skills of our training faculty who play a critical role in the intellectual development of our trainees. Finally, we will ensure that our training environment continues to be one in which all of our students can flourish.

大学遗传学和基因组学计划（utgg）有近40年的培训历史杜克大学的研究生。多年来，该计划一直保持其状态通过与实验和分析技术的变化共同发展，研究生培训计划，科学文化，职业发展和学生人口统计。目前，抬高是一个学位 - 授予大约50名学生和90位教职员工的计划医学院，工程学和艺术与科学学院。鲍格学生有有机会在包括染色体在内的各种基本研究问题中进行培训核酸和基因表达；发育遗传学，人群和进化遗传学；模型系统遗传学，人类和哺乳动物遗传学，植物遗传学；和微生物和病毒遗传学。我们的教职员工培训学生的实验和定量/分析方法从微生物到植物再到人类的各种生物系统。这种智力多样性，再加上杜克的高度协作文化创造了一个真正的跨学科培训环境。我们的斗篷校友从传统的学术研究和教学到工业/政府研究或监管事务，以及大型制药公司的小型初创公司。我们的当前的学员来自各种科学，文化和社会经济背景。这多样化的人群通过组织我们的一些签名来积极参加自己的培训课程，例如年度学生务虚会，杰出的讲座系列和社区宣传努力。其他程序化产品，例如我们的星期二研讨会系列，是焦点将整个遗传学和基因组学社区聚集在一起。在即将到来赠款期，我们试图利用竞选的当前优势和成功开发新的计划和课程产品，以支持知识和职业我们的培训的发展。我们的目标是利用遗传学和基因组学研究的背景在杜克（Duke）生产的独立科学家他们在一系列科学职业道路上蓬勃发展所需的领导能力和运营技能。作为我们将专注于学生培训的一部分，我们将开发提高心理技能的机制我们的培训教师在学员的智力发展中起着至关重要的作用。最后，我们会的确保我们的培训环境继续是我们所有学生都可以荧光的培训环境。

项目成果

期刊论文数量（17）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Mechanism of commitment to a mating partner in Saccharomyces cerevisiae.

DOI：
10.1091/mbc.e22-02-0043
发表时间：
2022-10-01
期刊：
MOLECULAR BIOLOGY OF THE CELL
影响因子：
3.3
作者：
Jacobs, Katherine C.;Gorman, Olivia;Lew, Daniel J.
通讯作者：
Lew, Daniel J.

Genome-wide screen identifies host loci that modulate Mycobacterium tuberculosis fitness in immunodivergent mice.

DOI：
10.1093/g3journal/jkad147
发表时间：
2023-08-30
期刊：
G3-GENES GENOMES GENETICS
影响因子：
2.6
作者：
Meade, Rachel K.;Long, Jarukit E.;Jinich, Adrian;Rhee, Kyu Y.;Ashbrook, David G.;Williams, Robert W.;Sassetti, Christopher M.;Smith, Clare M.
通讯作者：
Smith, Clare M.

Pheromone Guidance of Polarity Site Movement in Yeast.

DOI：
10.3390/biom12040502
发表时间：
2022-03-26
期刊：
Biomolecules
影响因子：
5.5
作者：
通讯作者：

Human genetic diversity regulating the TLR10/TLR1/TLR6 locus confers increased cytokines in response to Chlamydia trachomatis.

DOI：
10.1016/j.xhgg.2021.100071
发表时间：
2022-01-13
期刊：
HGG advances
影响因子：
0
作者：
Barnes AB;Keener RM;Schott BH;Wang L;Valdivia RH;Ko DC
通讯作者：
Ko DC

Cell-type specific transcriptional adaptations of nucleus accumbens interneurons to amphetamine.

DOI：
10.1038/s41380-022-01466-1
发表时间：
2023-08
期刊：
MOLECULAR PSYCHIATRY
影响因子：
11
作者：
Gallegos, David A.;Minto, Melyssa;Liu, Fang;Hazlett, Mariah F.;Yousefzadeh, S. Aryana;Bartelt, Luke C.;West, Anne E.
通讯作者：
West, Anne E.