Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS)

乔治城-霍华德大学临床与转化科学中心 (GHUCCTS)

• 批准号: 10624213
• 负责人: MARJORIE C GONDRE-LEWIS
• 金额: $ 282.73万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-28 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10624213
• 关键词: Academia; Acceleration; Achievement; Address; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Collaborations; Communities; Computing Methodologies; Cultural Backgrounds; Degree program; Disabled Persons; Discipline; District of Columbia; Education; Elderly; Enrollment; Ethnic Origin; Faculty; Funding; Future; Goals; Grant; Health; Health Professional; Home; Informatics; Infrastructure; Institution; Interdisciplinary Study; Laboratories; Leadership; Location; Longevity; Master of Science; Medical center; Mentorship; Minority-Serving Institution; Mission; Modeling; Multi-Institutional Clinical Trial; National Center for Advancing Translational Sciences; Patient Care; Persons; Population; Process; Public Health; Research; Research Institute; Research Personnel; Risk; Role; Science; Scientist; Speed; Students; System; TNFSF15 gene; Training; Training Programs; Training and Education; Translational Research; Translations; Underrepresented Populations; Underserved Population; United States Department of Veterans Affairs; Universities; Veterans; Washington; analytical method; career; career development; catalyst; clinical center; clinical translation; design; health determinants; health disparity; improved; innovation; inter-institutional; interdisciplinary collaboration; member; new technology; programs; racial diversity; research study; translational scientist

The Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) is a primary partnership of Georgetown University (GU) and Howard University (HU), with 3 affiliated institutions: MedStar Health Research Institute (MHRI), Oak Ridge National Laboratory (ORNL), and the Washington DC Veterans Affairs Medical Center (DCVAMC). This application is for our second competitive renewal. The specific aims of GHUCCTS are presently: 1) To continue to improve the infrastructure that supports high quality, interdisciplinary clinical and translational research, both via inter-institutional collaborations among GHUCCTS institutions as well as multicenter clinical trials across the national CTSA consortium, with increasing efficiency; 2) To further establish GHUCCTS as a model of inter-institutional collaboration that leverages the strengths and attributes of its diverse participating institutions in order to maintain GHUCCTS as a regional CTSA hub with unique and synergistic strengths; 3) To leverage our location, expertise and the co-leadership of a minority-serving institution to design, implement and disseminate clinical and translational research that will have a high impact on populations with health disparities, particularly underserved groups in our communities who have been historically under- represented in clinical research studies, including people from diverse racial, ethnic, and cultural backgrounds, people with disabilities, older adults and Veterans; 4) To continue to provide new vibrant and innovative educational programs for multiple levels of trainees, faculty and staff that promote principles of team science, and to provide the high quality career development training and support for the clinical and translational investigators of the future; and 5) To continue to apply and develop innovative analytical and computational methods to speed and enhance translation. In achieving these specific aims and their corresponding strategic goals we will draw from and contribute to the collective efforts and mission of the National Center for Advancing Translational Science (NCATS), and the national CTSA consortium. In the first 8 years as a funded CTSA program, GHUCCTS evolved into a fully functional multi-institutional center that has transformed CTR across each of the GHUCCTS member institutions with growing inter-institutional and inter-disciplinary collaboration and mentorship. Enrollment of under-represented groups is high in our research studies, and have increased to levels that more than double the national CTSA hub mean in our training programs. We have designed a new core in collaboration with ORNL that leverages their novel technologies to address environmental determinants of health risk in the District of Columbia. We will continue designing and refining innovative GHUCCTS programs to train the clinical and translational scientists and leaders of the future, and to disseminate these educational programs across the full spectrum of students, trainees and healthcare professionals at our GHUCCTS institutions and the national CTSA network.

乔治敦-霍华德大学临床与翻译科学中心(GHUCCTS)是一家 乔治敦大学(GU)和霍华德大学(HU)的合作伙伴关系，以及3个附属机构：MedStar 健康研究所(MHRI)、橡树岭国家实验室(ORNL)和华盛顿特区退伍军人 事务医疗中心(DCVAMC)。此申请表是针对我们的第二次竞争续签。的具体目标 GHUCCTS目前的目标是：1)继续改善支持高质量、跨学科的基础设施 临床和转化性研究，这两个都是通过GHUCCTS机构之间的机构间合作 作为跨国家CTSA财团的多中心临床试验，效率不断提高；2)进一步建立 GHUCCTS作为机构间合作的典范，利用其各种 参与机构，以保持环发中心作为区域协调中心的独特和协同作用 优势；3)利用我们的地理位置、专业知识和一家为少数族裔服务的机构的共同领导来设计， 实施和传播临床和转化性研究，这些研究将对患有 健康差距，特别是我们社区中服务不足的群体，他们历史上一直处于- 在临床研究中有代表性，包括来自不同种族、民族和文化背景的人， 残障人士、老年人和退伍军人；4)继续提供充满活力和创新的新 为多个层次的受训者、教职员工提供的教育计划，以促进团队科学的原则，以及 为临床和翻译研究人员提供高质量的职业发展培训和支持 5)继续应用和开发创新的分析和计算方法，以加快和 加强翻译。在实现这些具体目标及其相应的战略目标方面，我们将借鉴 并为国家促进翻译科学中心的集体努力和使命做出贡献 (NCATS)和国家CTSA财团。 在作为CTSA资助计划的头8年里，GHUCCTS发展成为一个功能齐全的多机构中心 这改变了GHUCCTS各成员机构的CTR，机构间和 跨学科协作和指导。在我们的研究中，代表不足的群体的入学率很高 学习，并且已经增加到超过国家CTSA中心的两倍的水平，这意味着我们的培训 程序。我们与ORNL合作设计了一个新的核心，利用他们的新技术来 解决哥伦比亚特区健康风险的环境决定因素。我们将继续设计和 完善创新的GHUCCTS计划，培养临床和转化型科学家和未来的领导者， 并在所有学生、受训人员和医疗保健人员中传播这些教育计划 我们的GHUCCTS机构和国家CTSA网络的专业人员。