J: NRSA Training Core

J：NRSA 培训核心

• 批准号: 10628056
• 负责人: JANICE L GABRILOVE
• 金额: $ 75.93万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-10 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10628056
• 关键词: Address; Adult Acute Lymphocytic Leukemia; Alzheimer' s Disease; Artificial Intelligence; Ascorbic Acid; Berry; Big Data; Biochemical; Bioethics; Bioinformatics; Biology; Biometry; Bone Marrow Transplantation; COVID-19; Carotid stent; Cephalic; Cerebrum; Citric Acid Cycle; Clinical; Clinical Informatics; Clinical Research; Clinical Sciences; Clinical Trials Design; Collaborations; Communities; Competence; Competency-Based Education; Complex; Computational Biology; Data; Data Science; Data Scientist; Development; Diabetes Mellitus; Discipline; Disease; Doctor of Philosophy; Dose; Ecology; Ecosystem; Education; Educational Curriculum; Engineering; Entrepreneurship; Enzymes; Epidemiology; Epigenetic Process; Ethics; Fellowship; Foundations; Funding; Genetic; Genomics; Goals; Government; Head and neck structure; Health; Health Sciences; Health system; Healthcare; Human; Image; Individual; Inflammatory Bowel Diseases; Institutes; Interdisciplinary Communication; Internal Medicine; Justice; Knowledge; Language; Leadership; Learning; Literature; Longevity; Lymphoma; Malignant Neoplasms; Medical; Medical Students; Medicine; Mentors; Mentorship; Methods; Modeling; Modernization; Multiple Myeloma; National Center for Advancing Translational Sciences; National Research Service Awards; Neck; Oral; Patients; Pattern; Pharmacogenetics; Phenotype; Physicians; Physiology; Procedures; Public Health; Radiation therapy; Recommendation; Reporting; Research; Research Design; Research Personnel; Research Training; Science; Scientist; Spasm; Statistical Computing; Surveys; TNFSF15 gene; Technology; Training; Training Activity; Training Programs; Translational Research; Underrepresented Populations; United States; United States National Institutes of Health; Vocabulary; Work; base; biomedical data science; brass; career; career development; clinically relevant; clopidogrel; data science education; design; digital health; disease disparity; doctoral student; equity diversity and inclusion; fecal transplantation; genome sciences; health disparity; health equity; high risk; implementation science; individualized prevention; innovation; insight; interdisciplinary collaboration; irradiation; lens; member; multidisciplinary; next generation; novel; patient oriented research; patient population; pedagogy; peer; post-doctoral training; pre-doctoral; precision medicine; programs; recruit; resilience; single fraction radiation; skills; social; success; tool; translational scientist; ultrasound; working group

The purpose of our NRSA TL1 Training Core is to develop, implement and disseminate innovative educational pipeline programs in transdisciplinary (TD) clinical and translational science (CTS), designed to launch the careers of the next generation of diverse translational investigators. Our socially responsible and ethically- grounded NRSA-TL1 pre-doctoral and postdoctoral trainees, equipped with epidemiology skills and data science acumen; teaming capacity; and a health equity, community lens, will be prepared to embrace the scientific and medical challenges of tomorrow and pursue novel healthcare solutions. As medicine increasingly tackles previously intractable, yet common complex diseases (e.g., Alzheimer’s, diabetes, cancer, COVID-19), transdisciplinary training in patient-oriented research needs to include data science. A deeper understanding of data science will harness the potential of the massive genetic, epigenetic, biochemical, administrative, and environmental data generated daily in medicine, government, science, and engineering. Our program will catalyze the development of the next generation of leaders in CTS and TD research by building upon our previously established CTSA-funded competency-based education programs, innovative data science education, novel toolkit of training activities and assessments; peer/near peer mentorship program and our highly productive and impactful Patient Oriented Research Training, And Leadership (PORTAL) program that supports both medical students and PhD students. We will additionally leverage our innovative, highly successful postdoctoral program-Sinai Team-based Translational Education Program: the Underrepresented in Medicine and Science (URiMS) Propeller (STTEP-UP) initiative, a novel training effort to advance the CTS careers of URiMS postdoctoral scientists (physicians and PhDs), previously recognized by NCATS for its work in promoting diversity across all NIH CTSA Hubs in the common metric of recruiting and training - underrepresented persons. Our efforts to realize modern CTS through TD research training of physician- scientists and PhD data scientists also takes advantage of our long-standing institutional commitment to big data research, as evidenced by our Biomedical Data Science Initiative, the Exposomics institute, the recently launched Masters and PhD programs in Genomics & Data Science and in Artificial Intelligence, the newly created Clinical Informatics Fellowship, as well as our proposed TD Education and Resilience Accelerators. Our strategically aligned, stage- and learner-specific transdisciplinary training pipeline initiatives aspire to provide novel models of successful CTS TD career development, including justice, equity, diversity and inclusion, as we work at the collaborative interface between data science, and the health of our communities in order to train, sustain and propel the CTS workforce of tomorrow.

我们的NRSA TL 1培训核心的目的是开发，实施和传播创新的教育 跨学科（TD）临床和转化科学（CTS）的管道计划，旨在推出 下一代不同的翻译研究者的职业生涯。我们的社会责任感和道德- 接地NRSA-TL 1博士前和博士后学员，配备流行病学技能和数据 科学敏锐度;团队能力;健康公平，社区透镜，将准备接受 未来的科学和医疗挑战，并寻求新的医疗保健解决方案。随着医学越来越 治疗以前难治的，但常见的复杂疾病（例如，老年痴呆症、糖尿病、癌症、COVID-19）， 面向患者的研究的跨学科培训需要包括数据科学。更深入地了解 数据科学将利用大规模遗传、表观遗传、生物化学、管理和 医学、政府、科学和工程领域每天产生的环境数据。我们的计划将 通过建立我们的基础，促进CTS和TD研究的下一代领导者的发展 以前建立的CTSA资助的基于能力的教育计划，创新的数据科学 教育，培训活动和评估的新工具包;同行/近同行辅导计划和我们的 高效和有影响力的以患者为导向的研究培训和领导力（门户）计划， 支持医学生和博士生。我们还将利用我们的创新，高度 成功的博士后计划-西奈团队为基础的翻译教育计划：在 医学和科学（URiMS）推进器（STTEP-UP）计划，一项推进CTS的新培训工作 URiMS博士后科学家（医生和博士）的职业生涯，以前由NCATS承认其工作 在招聘和培训的共同指标中，促进所有NIH CTSA中心的多样性 - 代表性不足的人。我们努力通过TD研究培训医生来实现现代CTS- 科学家和博士数据科学家还利用我们长期以来的机构承诺， 数据研究，正如我们的生物医学数据科学计划，Exposomics研究所，最近 启动了基因组学和数据科学以及人工智能的硕士和博士课程， 创建了临床信息学奖学金，以及我们提议的TD教育和恢复力加速器。 我们的战略一致，阶段和学习者特定的跨学科培训管道计划渴望 提供成功的CTS TD职业发展的新模式，包括正义，公平，多样性和 包容性，因为我们在数据科学和我们社区的健康之间的协作界面工作， 为了培训，维持和推动未来的CTS劳动力。