Conduits: MSHS Translational Science Hub

管道：MSHS 转化科学中心

• 批准号: 9260964
• 负责人: JANICE L GABRILOVE
• 金额: $ 43.67万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-15 至 2020-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9260964
• 关键词: Address; Arts; Bachelor' s Degree; Big Data; Biomedical Computing; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Communities; Critical Thinking; Data Analytics; Development; Development Plans; Discipline; Education; Educational Models; Engineering; Ensure; Fellowship; Fostering; Funding; Game Based Learning; Genomics; Goals; Health; Health Sciences; Healthcare Systems; Human; Incubators; Individual; Industry; Institutes; Intervention Trial; Investments; Knowledge; Laboratories; Leadership; Learning; Longevity; Medical Students; Medicine; Mentors; Mentorship; Methodology; Minority Participation; Modeling; Participant; Pathway interactions; Physicians; Population; Positioning Attribute; Recommendation; Recruitment Activity; Research; Research Methodology; Research Personnel; Research Training; Residencies; Resources; STEM field; Science; Scientist; Social Sciences; Societies; Students; TNFSF15 gene; Talents; Textiles; Therapeutic; Training; Training Programs; Translational Research; Translations; Underrepresented Minority; base; career; career development; design; disadvantaged student; education research; experience; improved; innovation; medical schools; member; minority trainee; next generation; novel; patient oriented research; peer coaching; personalized medicine; population based; programs; prototype; science education; simulation; skills; tool; training opportunity; translational pipeline; translational scientist; workforce needs

The overarching goal of the proposed TL1 training program for Conduits, the Institute for Clinical and Translational Sciences, is to develop innovative educational experiences in clinical translational science thereby fostering recruitment, training, mentorship and retention of talented individuals from diverse backgrounds who are inspired to engage in team science to improve human health. The proposed program is specifically designed to directly address singular unmet needs, challenges and recommendations for strengthening the clinical investigator pipeline: 1) lack of diversity within the current workforce, with strong endorsement for significant investments in fostering the emergence of minority participation in translational science leadership; and 2) diminishing numbers of MD physician-scientists and summary recommendations for CTSA provisions of funding for medical students to earn a Master’s in Clinical Research. To address these specific challenges we propose two specific training opportunities under the TL1 umbrella: 1) the Sinai Team-based Translational Education Program: the URM Propeller (STTEP UP) Initiative for Science and Medicine, designed for URM post-baccalaureate (STEM fields: 4 students per year) and postdoctoral (residents and subspecialty fellows in particular: 4 students per year) trainees; and 2) the new entry (after completion of the first year of medical school) PORTAL (MD/MSCR) program (3 students/year), designed to attract medical students (in particular URM and financially disadvantaged students) who may not have previously been afforded the chance to consider this type of career opportunity. This training effort will leverage our partnership with Rensselaer Polytechnic Institute (RPI), and the scientific, clinical, and educational expertise of ISMMS and the MSHS. These efforts will also build upon previous CTSA-funded and inspired institutional investments in translational therapeutics, genomics, BIG Data analytics, personalized medicine, population specific health and clinical trials expertise, community engagement, team science and mentorship. To optimize and enrich this training effort we have woven into the fabric of our curricular efforts, the programmatic strengths and expertise of other components of this CTSA proposal and will capitalize upon previously established and ongoing collaborations with education leaders at other CTSA Hubs. Finally, to more effectively educate our trainees in translational science we will develop and implement novel game-based learning tools, in collaboration with the Games and Simulation Arts and Science Program at RPI. We propose to create and disseminate models of early pipeline programs designed to specifically address the needs of under-represented minority (URM) members of the translational research workforce. The educational programs described will foster critical thinking as well as the acquisition of methodological skills and principles of productive teamwork, to enable individuals with discipline-related knowledge to apply their expertise to develop translational science research programs that will accelerate discovery to improve health.

拟议的针对款TL1培训计划的总体目标，临床研究所和 翻译科学是为了发展临床转化科学的创新教育经验 从而促进来自潜水员的才华横溢的人的招聘，培训，精神训练和保留 受到启发参与团队科学以改善人类健康的背景。拟议的程序是 专门设计用于直接满足单数未满足的需求，挑战和建议 加强临床研究人员管道：1）当前劳动力中缺乏多样性， 认可大量投资，以促进少数群体参与转化的出现 科学领导； 2）减少MD物理科学家和摘要数量 针对医学生的CTSA资金规定的建议，以赢得临床硕士学位 研究。为了应对这些具体挑战，我们在TL1下提出了两个特定的培训机会 伞：1）基于西奈团队的转化教育计划：URM螺旋桨（STTEP）倡议 用于科学和医学，专为URM后核后龙（STEM领域：每年4个学生）和 博士后（特别是居民和亚专业人士：每年4个学生）培训； 2）新的 进入（医学院第一年完成后）门户网站（MD/MSCR）计划（3名学生/年）， 旨在吸引医学生（尤其是URM和经济困扰的学生） 以前有机会考虑这种职业机会。这项训练工作将 利用我们与Rensselaer理工学院（RPI）以及科学，临床和 ISMM和MSHS的教育专家。这些努力还将基于以前的CTSA资助，并且 激发了转化疗法，基因组学，大数据分析，个性化的机构投资 医学，人群特定健康和临床试验专业知识，社区参与，团队科学和 脑膜。为了优化和丰富这项培训工作，我们已经编织成课程努力的结构， 该CTSA提案的其他组成部分的计划优势和专业知识，并将利用 以前与其他CTSA枢纽的教育领袖建立了持续的合作。最后，更多 有效地教育我们的受训者，我们将开发和实施基于游戏的新颖 学习工具，与RPI的游戏和仿真艺术与科学计划合作。我们建议 创建和传播旨在专门满足需求的早期管道计划的模型 转化研究人员的代表性不足的少数民族（URM）成员。教育计划 所描述的将培养批判性思维以及获取方法论技巧和原理 有效的团队合作，使具有纪律相关知识的个人运用其专业知识以发展 转化科学研究计划将加速发现以改善健康。