Regional Biocontainment Laboratory (RBL) Upgrade for Colorado State University (CSU)

科罗拉多州立大学 (CSU) 区域生物防护实验室 (RBL) 升级

• 批准号: 10631549
• 负责人: Karen Marie Dobos
• 金额: $ 319.32万
• 依托单位: COLORADO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-23 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10631549
• 关键词: 2019-nCoV; Address; Air; Air Conditioning; Air Movements; American; Animal Husbandry; Animal Model; Animal Welfare; Animals; Antimicrobial Resistance; Area; Automation; Avian Influenza; Award; Biological Models; Bioterrorism; Bunyavirales; COVID-19; Centers for Disease Control and Prevention (U.S.); Collaborations; Colorado; Communicable Diseases; Complex; Containment; Coronavirus; Dengue; Diagnosis; Disease; Domestic Animals; Educational process of instructing; Educational workshop; Emergency Situation; Emerging Communicable Diseases; Ensure; Equipment; Event; Evolution; Fellowship; Ferrets; Flaviviridae; Funding; Genus Mycobacterium; Grant; Heating; Image; In Vitro; Individual; Infection; Infectious Diseases Research; Infrastructure; Institution; Interdisciplinary Study; Investments; Knowledge; Laboratories; Maintenance; Malaria; Microscopic; Mission; Modeling; Modernization; Molecular; Monoclonal Antibodies; Mus; NCI Scholars Program; National Institute of Allergy and Infectious Disease; Organism; Oryctolagus cuniculus; Parents; Performance; Prevention; Public Health; Research; Research Activity; Research Personnel; Research Support; Research Training; Resources; Rodent; Safety; Services; Sterility; Sterilization; Support System; System; Temperature; Therapeutic; Time; Togaviridae; Training; Tuberculosis; Universities; Update; Ursidae Family; Vaccines; Virulent; Water; Work; Zika Virus; animal care; base; biodefense; cost; design; emerging pathogen; improved; in vivo; operation; pathogen; pathogenic bacteria; pathogenic virus; prevent; programs; repaired; research facility; response; spillover event; success; symposium; synergism; vector-borne; ventilation; visiting scholar

Project Summary / Abstract The funding and implementation of this supplement is essential to maintain uninterrupted research and scholarly activity in CSU’s Rocky Mountain Regional Biocontainment Laboratory (RMRBL). Research activities that occur at the RMRBL directly address the RBLs’ missions to respond to and prevent global infectious disease threats. Our efforts are the evolution of over 4 decades of research conducted at CSU predominately sponsored by NIAID, and includes interdisciplinary research teams studying Flaviviridae, Togaviridae, Bunyavirales, Coronaviridae viral pathogens along with robust programs in mycobacteria, anti microbial resistance, and vector borne bacterial pathogens. The RBL is integral for this infectious disease research, training and other scholarly activities. The RMRBL recently benefitted from a G20 award specific to much needed modernization and infrastructure upgrades. However, these investments continue to be needed due to the complexity and high use of this facility. Here, we add to the Specific Aims of our parent G20 award to continue to make critical investments to improve our biosafety, animal modeling, and imaging research needs.

项目总结/摘要 资助和实施这一补充是必不可少的，以保持不间断的研究， CSU的落基山脉区域生物遏制实验室（RMRBL）的学术活动。研究 在RMBL上进行的活动直接涉及RMBL响应和防止全球 传染病威胁。我们的努力是在CSU进行的40多年研究的演变 主要由NIAID赞助，包括研究黄病毒科的跨学科研究小组， 披膜病毒科、布尼亚病毒目、冠状病毒科病毒病原体沿着分枝杆菌的强大程序， 抗微生物抗性和载体携带的细菌病原体。RBL是这种传染病的组成部分， 疾病研究、培训和其他学术活动。RMRBL最近受益于G20 该奖项专门针对急需的现代化和基础设施升级。然而，这些投资 由于该设施的复杂性和高使用率，仍然需要。在这里，我们添加到具体的 我们的母公司G20奖项的目标是继续进行关键投资，以改善我们的生物安全、动物安全 建模和成像研究的需求。