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中文摘要
翻译
项目概要-药物研究中心(DRP) SPORE发展研究计划(DRP)的目标是识别和支持令人兴奋的 前列腺癌的研究,并确保在高质量的科学努力不断更新, 孢子。该计划将招募不同的学科和背景,带来新鲜的想法和新的 前列腺癌的治疗方法DRP还将创造支持招聘的机会, 保留妇女和在外地任职人数不足的种族和族裔群体。将征求申请 由一个高素质和积极参与的委员会进行广泛和公正的审查。DRP受助人将成为 SPORE社区,提供曝光、反馈和对核心资源的访问。将监测进展情况, 并会协助及鼓励受助人申请其他资助机会。总的来说,DRP将 最大限度地增加由有希望的试验数据支持的新的和尖端的概念有机会 有能力获得更大的赠款资金,并最终影响外地。这将通过以下方式实现: 以下具体目标:1)通过以下方式促进创新和有前途的前列腺癌研究的发展: 为从区域合作机构征求的评级最高的项目提供种子资金; 2)确定并优先考虑 招标的重点是有可能对改善成果产生最大影响的领域, 前列腺癌患者,特别关注代表性不足的种族和民族群体; 3)监测 发展项目的进展,提供关键和及时的反馈,并鼓励和支持 有前途的DRP项目竞争校外同行评审的资金。在必要和有希望的时候, 将最有价值的DRP项目提升为完整的SPORE研究项目; 4)将新的研究人员引入 前列腺癌转化研究,特别努力招募女性和研究人员, 代表种族和民族群体。
英文摘要
PROJECT SUMMARY– DEVELOPMENTAL RESEARCH PROGRAM (DRP) The objective of the SPORE Developmental Research Program (DRP) is to identify and support exciting prostate cancer research and ensure a continuous renewal of high-quality scientific endeavors within the SPORE. The program will recruit diverse disciplines and backgrounds to bring fresh ideas and new approaches to prostate cancer. The DRP will also create opportunities that support the recruitment and retention of women and underrepresented racial and ethnic groups in the field. Applications will be solicited broadly and reviewed fairly by a highly qualified and engaged committee. DRP recipients will become part of the SPORE community with exposure, feedback, and access to core resources. Progress will be monitored, and recipients will be helped and encouraged to apply for other funding opportunities. Overall, the DRP will maximize the chance that new and cutting-edge concepts supported by promising pilot data have the capability to receive larger grant funding and ultimately impact the field. This will be achieved through the following specific aims: 1) Foster the development of innovative and promising prostate cancer research by providing seed funding to the highest rated projects solicited from RFAs; 2) Identify and prioritize solicitations focused on areas of with the potential to have the highest impact of improving the outcome of patients with prostate cancer, with a specific focus on underrepresented racial and ethnic groups; 3) Monitor the progress of developmental projects, provide critical and timely feedback, and encourage and enable promising DRP projects to compete for extramural peer- reviewed funding. When necessary and promising, promote the most meritorious DRP projects to full SPORE research projects; 4) Bring new investigators into prostate cancer translational research with specific efforts to recruit females and investigators from under- represented racial and ethnic groups.
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Elucidating prostate cancer risk mechanisms through large-scale cistrome wide association studies
  • 批准号:
    10686418
  • 项目类别:
  • 资助金额:
    $66.05万
  • 财政年份:
    2022
  • 负责人:
    MATTHEW L FREEDMAN
  • 依托单位:
Common biology underlying pleiotropic breast, prostate and ovarian cancer risk loci
  • 批准号:
    10366397
  • 项目类别:
  • 资助金额:
    $66.84万
  • 财政年份:
    2022
  • 负责人:
    MATTHEW L FREEDMAN
  • 依托单位:
Common biology underlying pleiotropic breast, prostate and ovarian cancer risk loci
  • 批准号:
    10684639
  • 项目类别:
  • 资助金额:
    $62.27万
  • 财政年份:
    2022
  • 负责人:
    MATTHEW L FREEDMAN
  • 依托单位:
Elucidation of the genetic mechanisms driving prostate tumorigenesis through integrative computational and functional approaches
  • 批准号:
    10576263
  • 项目类别:
  • 资助金额:
    $66.14万
  • 财政年份:
    2021
  • 负责人:
    MATTHEW L FREEDMAN
  • 依托单位:
国内基金
海外基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
  • 批准号:
    2021JJ40433
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2021
  • 负责人:
    孙磊
  • 依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
  • 批准号:
    32001603
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2020
  • 负责人:
    段真珍
  • 依托单位:
AREA国际经济模型的移植.改进和应用
  • 批准号:
    18870435
  • 项目类别:
    面上项目
  • 资助金额:
    2.0万元
  • 批准年份:
    1988
  • 负责人:
    史树中
  • 依托单位: