课题基金 / 基金详情

Predoctoral Program in Biophysics

Predoctoral Program in Biophysics
生物物理学博士前课程
批准号:
10628233
负责人:
Yong Xiong
金额:
$63.66万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-07-01 至 2028-06-30

项目摘要

项目成果

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中文摘要
翻译
项目摘要 耶鲁生物物理学培训计划(BTP)的目标是为博士前学员提供知识和技能, 研究基金会成为生物物理和生物医学科学前沿的未来领导者。的 拟议的BTP利用了我们之前长达34年的生物物理学培训计划的优势, 结合大量新的重点,以适应迅速发展的研究企业。BTP是一个博士- 跟踪程序,提供了广泛的生物系统和生物物理技术的培训,使 在分子水平上理解生命过程的机制。BTP结合了严格的研究 在高度互动的环境中进行培训,并在生物物理学方面进行全面的学术课程, 职业和技能发展的机会。该计划利用了深刻而多样的生物物理学 耶鲁大学的申请人以及来自许多大学的43名教师培训师的非凡研究实力 包括分子生物物理学和生物化学(MB&B),化学,药理学,免疫学, 和细胞生物学BTP项目总监熊勇和艾尔莎严密切合作,监督该项目 并与另外四名教师一起,组成BTP执行委员会,制定新的举措, 根据内部和外部评审评估项目的成功,并监督受训人员和BTP教师 评价和任命。BTP领导层还将确保我们的学员在一个 道德,包容和安全的环境。主要的培训实体是MB&B部门和 化学系。学生可以直接通过化学系进入BTP, 从MB&B部门通过伞生物和生物医学科学(BBS)计划,主要来自 生物化学,定量生物学,生物物理学和结构生物学(BQBS)轨道。学员被选中 根据生物物理学的研究重点,在第二年任命BTP。BTP培训涉及正式课程 工作,研究轮换,教学和资格考试在1-2年,与论文研究开始在春季 第一年。加入导师实验室后,论文研究将在论文的监督下进行 委员会由至少三名熟悉学生研究课题的教师组成,并定期开会 讨论进展培训通过强化辅导在严谨性,可重复性和负责任的行为丰富 研究,前往主要的生物物理学会议,广泛的宣传,指导和多样性参与,以及 合作和互动的机会很多。我们还在开发专门的评估工具, 进行调查,以衡量受训人员的发展情况,并指导今后的改进。所有学员的成果将存入 在BTP网站上的一个容易访问的数据库中。耶鲁大学的培训资源和 通过导师对培训的承诺,促进BTP培养下一代科学领导者的目标。 BTP要求12个培训职位,每年任命6名二年级和6名三年级学生。
英文摘要
Project Summary The goal of the Yale Biophysics Training Program (BTP) is to equip predoctoral trainees with the intellectual and research foundations to become future leaders at the forefront of biophysical and biomedical sciences. The proposed BTP leverages the strengths of our previous 34 year-long program in biophysics training while incorporating substantial new focuses to adapt to the rapidly evolving research enterprise. The BTP is a PhD- track program that offers training in a wide range of biological systems and biophysical techniques to enable understanding the mechanisms of life processes at the molecular level. The BTP combines rigorous research training in a highly interactive environment and a thorough academic program in biophysics with diverse opportunities for career and skill development. The program takes advantage of the deep and diverse biophysics applicant pool at Yale as well as the extraordinary research strengths of 43 faculty trainers from many departments including Molecular Biophysics and Biochemistry (MB&B), Chemistry, Pharmacology, Immunology, and Cell Biology. BTP Program Directors Yong Xiong and Elsa Yan work together closely to oversee the program and together with four additional faculty, constitute the BTP Executive Committee, which develops new initiatives, evaluates program success based on internal and external reviews, and oversees trainee and BTP faculty evaluations and appointments. The BTP leadership will additionally ensure that our trainees thrive within an ethical, inclusive, and safe environment. The principal training entities are the MB&B Department and the Chemistry Department. Students are admitted to the BTP either directly through the Chemistry Department or from MB&B Department through an umbrella Biological and Biomedical Sciences (BBS) Program, primarily from the Biochemistry, Quantitative Biology, Biophysics, and Structural Biology (BQBS) track. Trainees are selected for BTP appointment in year 2 based on a research focus in biophysics. BTP training involves formal course work, research rotations, teaching, and qualifying exam in years 1-2, with thesis research beginning in the spring of year one. Upon joining a mentor lab, dissertation research is performed with supervision from a thesis committee comprised of at least three faculty that are familiar with the student's research topic and meet regularly to discuss progress. Training is enriched by intensive coaching in rigor, reproducibility, and responsible conduct of research, travel to major biophysics meetings, extensive outreach, mentoring, and diversity engagement, and numerous opportunities for collaboration and interaction. We are also developing special assessment tools and surveys to measure trainee development and guide future improvements. All trainee outcomes will be deposited into an easily accessible databank on the BTP website. The training resources at Yale and the dedicated commitment to training by the mentors, facilitate the BTP goal to produce the next-generation leaders in science. The BTP requests 12 training positions to appoint 6 second-year and 6 third-year students per year.
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Multifaceted interactions between lentiviral Vif and host molecules for viral infectivity enhancement
  • 批准号:
    10640135
  • 项目类别:
  • 资助金额:
    $47.83万
  • 财政年份:
    2015
  • 负责人:
    Yong Xiong
  • 依托单位:
Multifaceted interactions between lentiviral Vif and host molecules for viral infectivity enhancement
  • 批准号:
    10326954
  • 项目类别:
  • 资助金额:
    $50.25万
  • 财政年份:
    2015
  • 负责人:
    Yong Xiong
  • 依托单位:
Recognition of Viral DNA by APOBEC3 Proteins and their Antagonization by HIV Vif
  • 批准号:
    8992425
  • 项目类别:
  • 资助金额:
    $41.49万
  • 财政年份:
    2015
  • 负责人:
    Yong Xiong
  • 依托单位:
Recognition of Viral DNA by APOBEC3 Proteins and their Antagonization by HIV Vif
  • 批准号:
    9079350
  • 项目类别:
  • 资助金额:
    $41.48万
  • 财政年份:
    2015
  • 负责人:
    Yong Xiong
  • 依托单位:
海外基金