Research Training in Gastrointestinal and Hepatic Diseases

项目总结 在基础生物医学、临床和转化科学方面不断加快的发现速度现在提供了 改变胃肠道和肝脏疾病患者护理的前所未有的机遇。在过去35年中 多年来，布里格姆妇女医院(BWH)为培养学术人才做出了重大贡献 寻求消化系统疾病治疗方法的胃肠病专家和肝病专家。来自BWH的此应用程序 请求为BWH的4名基础和临床/翻译研究员的研究培训提供支持 为额外的培训时段提供资金。兴趣浓厚、踏实的优秀应聘者 将招募和培训研究基金会，以应用他们的知识和技能来解决 在预防、诊断和治疗胃肠道疾病患者方面未得到满足的重要临床需求 肝脏疾病。学员将获得为期两年的计划支持，在此期间，他们将遵循结构化的 和严谨，但个性化的培训计划。这将是25位杰出和多样化的人的共同努力 来自波士顿儿童医院、达纳·法伯癌症研究所、哈佛医学院、 哈佛大学公共卫生学院、麻省理工学院和博德学院。 这些导师构成了一个合作研究人员的网络，他们是该领域的国际领导者 与胃肠病和肝病有直接关系。它们被组织成4个主题，但 相互关联的研究培训单位：细胞生物学、免疫学和微生物学；新陈代谢和 生物工程；基因、干细胞和发育；以及临床和翻译科学。这些培训 各单位将提供针对具体内容的教育方案，并将提高行政效率 在培训计划中。监督将由研究培训执行委员会提供，包括 方案主任和2名副方案主任，他们也将担任教务长。其他内容 成员将就指导以及在培训中实现和保持多样性提供指导 程序。一批优秀的内部和外部咨询委员会成员将对该计划进行评估 提供具体建议，以提高研究的质量、多样性、效率和附加值 培训我们最有前途的胃肠病研究员。这项高度个性化的培训计划将包括： 1)个人发展计划；2)严格的研究培训；3)前沿实践经验 方法论；4)综合课程。学员将进一步受益于广泛的机构 参会机构的资源和丰富的智力环境。根据持续的水平 我们对我们的奖学金计划感兴趣，我们预计会有大量高素质的候选人，并将 保持高度重视多样性。通过严谨、结构化和高度个性化的课程，这 培训计划确认其致力于培训未来消化系统疾病研究的领导者 准备将他们的发现转化为改善患者护理。

PROJECT SUMMARY The accelerating pace of discovery in the basic biomedical, clinical and translational sciences now provides unprecedented opportunities to transform patient care in gastrointestinal and liver diseases. Over the past 35 years, Brigham and Women’s Hospital (BWH) has made major contributions to the training of academic gastroenterologists and hepatologists seeking cures for digestive diseases. This application from BWH requests support for the research training of 4 basic and clinical/translational research fellows, with BWH providing funding for an additional training slot. Outstanding candidates with strong interests and solid foundations in research will be recruited and trained to apply their knowledge and skills towards addressing important unmet clinical needs in the prevention, diagnosis, and treatment of patients with gastrointestinal and hepatic diseases. Trainees will receive program support for 2 years during which they will follow a structured and rigorous, but individualized training program. This will be a joint effort of 25 eminent and diverse preceptors from BWH, Boston Children’s Hospital, Dana Farber Cancer Institute, Harvard Medical School, the Harvard T.H. Chan School of Public Health, Massachusetts Institute of Technology and the Broad Institute. These preceptors constitute a network of collaborative researchers, who are international leaders in fields directly relevant to gastroenterology and hepatology. They have been organized into 4 themed, but interconnected research training units: cell biology, immunology and microbiology; metabolism and bioengineering; genes, stem cells and development; and clinical and translational sciences. These training units will provide content-specific educational programming and will increase the efficiency of administration within the training program. Oversight will be provided by a Research Training Executive Committee including the Program Director and 2 Associate Program Directors, who will also serve as preceptors. Additional members will provide guidance on mentoring and on achieving and maintaining diversity within the training program. An outstanding roster of internal and external advisory board members will evaluate the program and provide specific recommendations that improve its quality, diversity, efficiency and value added to the research training of our most promising gastroenterology fellows. This highly personalized training program will include: 1) individual development plans; 2) rigorous research training; 3) hands-on experience in cutting-edge methodologies, and; 4) an integrated curriculum. Trainees will further benefit from the extensive institutional resources and rich intellectual environment of the participating institutions. Based upon the sustained levels of interest in our fellowship program, we anticipate a substantial pool of highly qualified candidates and will maintain a strong focus on diversity. Through its rigorous, structured and highly personalized curriculum, this training program affirms its commitment to training future leaders in digestive disease research who are prepared to translate their findings towards improving patient care.