Multidisciplinary Research Training in Gastroenterology and Hepatology

项目摘要 人类基因组测序的成功和人类健康服务研究的发展 后基因组时代为改变消化系统疾病的患者护理提供了前所未有的机会。 在过去的十年中，威尔康奈尔医学（WCM）在生物医学研究方面进行了重大投资， 以及研究培训和基础设施。WCM的这份申请要求支持这项研究 在一个新的多学科研究培训方案中培训4名临床和非临床博士后研究员 在胃肠病学和肝病学方面，WCM为额外的培训名额提供资金。的 目标是招募在基础科学方面有坚实基础的优秀候选人，并培养他们应用 他们的知识和技能，以解决重要的临床未满足的需要，在预防，诊断， 以及消化系统疾病患者的治疗。MRTP学员将获得为期2年的计划支持 在此期间，他们将遵循一个结构化和严格的博士后培训计划。MRTP将是一个联合 来自WCM，纪念斯隆凯特琳癌症中心（MSKCC）和 洛克菲勒大学（RU），构成了一个密集的合作研究人员网络，他们是 胃肠病学和肝病学领域的国际领导者。这些导师有 被组织成3个主题，但相互关联的研究培训单位：胃肠道恶性肿瘤，肝脏 疾病和再生，以及粘膜免疫学和炎症。这些培训单位将使 制定具体内容的教育方案，以及提高行政效率 在训练计划中。将由一个研究培训执行委员会进行监督， 项目主任和2名副项目主任，他们也将担任培训单位的领导， 以及另外3名将提供临床/流行病学研究具体指导的成员， 在培训计划中实现和保持多样性，以及指导。我们还组织了一个 内部和外部咨询委员会成员的杰出名册，其任务是评估该计划 并提出具体建议，以提高其质量和效率。MRTP的高度 个性化的培训计划将包括1）个人发展计划; 2）严格的研究培训; 3） 尖端方法的实践经验;和4）综合课程。学员将进一步 受益于WCM、MSKCC和RU的广泛机构资源。根据兴趣的程度 在我们的奖学金计划中，我们预计将有大量高素质的临床和非临床 建议的MRTP的候选人，这将保持一个强大的多样性重点。通过其严格的， 结构化和高度个性化的课程，这个新的培训计划旨在培养未来的领导者， 消化系统疾病的研究谁准备转化为改善病人护理他们的发现。

PROJECT SUMMARY The successful sequencing of the human genome and the evolution of human health services research in the post-genomic era have offered unprecedented opportunities to transform patient care in digestive diseases. Over the past decade, Weill Cornell Medicine (WCM) has made major investments in biomedical research, as well as research training and infrastructure. This application from WCM requests support for the research training of 4 clinical and non-clinical postdoctoral fellows in a new multidisciplinary research training program (MRTP) in Gastroenterology and Hepatology, with WCM providing funding for an additional training slot. The objective is to recruit outstanding candidates with solid foundations in basic science and train them to apply their knowledge and skills towards addressing important clinically unmet needs in the prevention, diagnosis, and treatment of patients with digestive diseases. MRTP trainees will receive program support for 2 years during which they will follow a structured and rigorous postdoctoral training program. The MRTP will be a joint effort of 28 eminent preceptors from WCM, Memorial Sloan Kettering Cancer Center (MSKCC) and the Rockefeller University (RU), which constitute a dense network of collaborative researchers, who are international leaders in fields directly relevant to gastroenterology and hepatology. These preceptors have been organized into 3 themed, but interconnected units of research training: gastrointestinal malignancies, liver diseases and regeneration, and mucosal immunology and inflammation. These training units will enable the development of content-specific educational programming, as well as increase the efficiency administration within the training program. Oversight will be provided by a Research Training Executive Committee consisting of the Program Director and 2 Associate Program Directors, who will also serve as leaders of the training units, as well as 3 additional members who will provide specific guidance on clinical/epidemiologic research, on achieving and maintaining diversity within the training program, and on mentoring. We have also assembled an outstanding roster of internal and external advisory board members with a mandate to evaluate the program and provide specific recommendations to improve both its quality and efficiency. The MRTP's highly personalized training program will include 1) individual development plans; 2) rigorous research training; 3) hands-on experience in cutting-edge methodologies; and 4) an integrated curriculum. Trainees will further benefit from the extensive institutional resources of WCM, MSKCC and RU. Based upon the levels of interest in our fellowship programs, we anticipate a substantial pool of highly qualified clinical and non-clinical candidates for the proposed MRTP, which will maintain a strong diversity focus. Through its rigorous, structured and highly personalized curriculum, this new training program seeks to train future leaders in digestive disease research who are prepared to translate their findings towards improving patient care.