Genetics & Genomics Training Program

此应用程序是在遗传学和基因组学博士前培训计划的支持请求， 贝勒医学院。该方案始于1987年，自1990年以来一直由NIGMS T32资助。 研究生院和分子和人类遗传学系遵循创新的三个原则 贝勒医学院的生物医学：研究，教育和服务。这个的使命 跨部门计划是培养博士生在经典和现代遗传学的基础知识， 将他们的知识和技能应用于生物医学创新。多样性和包容性是不可或缺的 这个使命的组成部分。我们的目标是为学生提供严格和有条不紊的培训， 遗传学和基因组学，同时强调研究和学术卓越，并帮助他们成为 下一代生物医学科学家的领导者。我们目前正在培养97名博士生， 在过去5年中增长了16%，我们计划在未来5年内培训100名新生。我们目前 有84名教师导师，在过去5年中增加了20%。他们的研究项目涵盖了广泛的领域， 兴趣，包括人类遗传学，基因组学，人类疾病的分子基础， 人类疾病、微生物遗传学、发育、神经生物学和基因组稳定性。的共同主题 这些主题包括遗传学和基因组学及其对人类健康的影响。中的培训要素 第一年包括基础和高级课程，实验室轮换和技能发展活动。 课程的重点是设计和分析基于遗传学的实验和旋转提供 个性化的实践研究经验。技能发展包括培训负责任的行为， 研究，基因组时代人类遗传学的伦理问题，实验的严谨性和可重复性， 科学、科学交流、批判性思维和团队合作。第二年，学生们加入 研究实验室，他们在我们的教师的指导下进行项目，因为他们开始他们的 走向独立的道路。他们还参加资格考试，培训他们将知识从 课程和文献，并设计一个原始的实验研究项目。除了培训， 在实验工作中，学生们学习如何分析他们的数据，如何口头和口头展示他们的发现， 写作，以及如何以一种合议和建设性的方式参与科学过程。学生们正在 还鼓励他们在整个培训期间参加职业发展活动。论文项目 在论文的准备和答辩中达到高潮。获得博士学位的平均时间为5.7 平均发表论文6.1篇，其中第一作者论文2.1篇。我们的留存率是 96%，我们的大多数校友在他们随后的职位上使用他们的培训。我们要求16个插槽，每个插槽8个 为配合我们不断提高的培训能力和 只有T32支持的遗传学和基因组学博士课程在得克萨斯州和休斯顿600英里半径内。

This application is a request for support for the Predoctoral Training Program in Genetics & Genomics at Baylor College of Medicine. This Program started in 1987 and has been funded by an NIGMS T32 since 1990. The Graduate School and the Department of Molecular and Human Genetics follow three tenets of innovative biomedicine at Baylor College of Medicine: Research, Education, and Service. The mission of this interdepartmental Program is to train PhD students in the fundamentals of classical and modern genetics and in application of their knowledge and skills to innovations in biomedicine. Diversity and inclusion are integral components of this mission. Our objectives are to provide students with rigorous and methodical training in genetics and genomics while emphasizing research and academic excellence, and to help them become leaders among the next generation of biomedical scientists. We are currently training 97 predoctoral students, an increase of 16% in the past 5 years, and we plan to train 100 new students in the next 5 years. We currently have 84 faculty mentors, an increase of 20% in the past 5 years. Their research projects span a wide range of interests, including human genetics, genomics, the molecular basis of human disease, animal models of human disease, microbial genetics, development, neurobiology, and genome stability. The common themes among these topics are genetics and genomics, and their translation to human health. The training elements in the first year include foundational and advanced courses, laboratory rotations, and skill development activities. The courses are focused on design and analysis of genetic-based experiments and the rotations provide individualized practical research experiences. Skill development includes training in the responsible conduct of research, ethical aspects of human genetics in the genomic era, rigor and reproducibility in experimental science, scientific communications, critical thinking, and teamwork. In the second year, the students join research laboratories in which they conduct projects under the mentorship of our faculty, as they begin their path to independence. They also take a qualifying examination that trains them to integrate knowledge from courses and from the literature and to design an original experimental research project. In addition to training in experimental work, the students learn how to analyze their data, how to present their findings orally and in writing, and how to participate in the scientific process in a collegial and constructive way. The students are also encouraged to participate in career development activities throughout their training. The thesis project culminates in the preparation and defense of a thesis dissertation. The average time to a PhD degree is 5.7 years and the average number of publications is 6.1, including 2.1 first-author papers. Our retention rate is 96%, and most of our alumni use their training in their subsequent positions. We are requesting 16 slots, 8 per year for the first 2 years of training, to match our increased training capacity and the proven success of the only T32-supported Genetics & Genomics PhD Program in Texas and within a 600 mile radius of Houston.