ShEEP Request for a Multimodal Plate Reader
ShEEP 请求多模式读板仪
基本信息
- 批准号:10738976
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-03-01 至 2023-09-30
- 项目状态:已结题
- 来源:
- 关键词:AccelerationAgingAntibodiesBiochemical ReactionBiologicalBiological AssayBiomedical ResearchCancer BiologyChemicalsDNADementiaDevicesDiagnosisDiseaseEnzyme-Linked Immunosorbent AssayEquipmentFluorescenceFluorescence PolarizationFundingGrowth FactorHealthHormonesKidney DiseasesKineticsLaboratoriesLifeLightLuciferasesMeasurementMeasuresMolecularPersian Gulf SyndromeProteinsQuality of lifeRNAReaderResearchResearch DesignScanningServicesSheepSpecific qualifier valueSpectrophotometrySpinal cord injuryTemperatureTestingTimeTraumatic Brain InjuryVeteransanticancer researchblood pressure controlbone lossdetectorimprovedinstrumentinstrumentationlaptoplight emissionluminescencemolecular dynamicsmultimodalityprotein protein interaction
项目摘要
The requested instrument is a Molecular Dynamics Spectramax id5 multi-mode Microplate reader
with dual injectors. It is used to perform assays based on spectrophotometry, fluorimetry, time-
resolved fluorescence and luminescence. This type of instrument is widely used in biomedical
research for measuring amounts of certain chemicals such as ATP and of biological substances such
as hormones, antibodies and growth factors. It can also be used to test for specific types of protein-
protein interactions. It will replace existing though aging equipment that is reaching the end of its
service life. It will also be adding capabilities our current instrumentation lacks, such as dual injectors
for use in flash assays such as measurement of ATP levels, and the capacity to make measurements
using 384-well plates. Its availability will enhance ongoing VA-funded projects focused on reducing
bone loss due to spinal cord injury, advancing understanding of the diagnosis and treatment of
dementia, greater understanding of Gulf War syndrome and other disorders related to miliary service,
traumatic brain injury, renal disease and blood pressure control. By doing so, the equipment will
accelerate the pace of VA research aimed at improving health and quality of life of Veterans.
所需仪器为Molecular Dynamics Spectramax id 5多模式酶标仪
双喷射器。它用于进行基于分光光度法、荧光法、时间-
分辨荧光和发光。这类仪器广泛应用于生物医学领域
测量某些化学物质(如ATP)和生物物质(如
激素抗体和生长因子它也可以用来测试特定类型的蛋白质-
蛋白质相互作用它将取代现有的,虽然老化的设备,这是达到其年底,
使用寿命它还将增加我们目前的仪器所缺乏的功能,例如双喷射器
用于快速测定,例如测量ATP水平,以及进行测量的能力
使用384孔板。它的提供将加强正在进行的VA资助的项目,重点是减少
脊髓损伤引起的骨丢失,提高对脊髓损伤的诊断和治疗的认识,
痴呆症,对海湾战争综合症和其他与粟粒性疾病有关的疾病的更多了解,
创伤性脑损伤、肾病和血压控制。通过这样做,设备将
加快旨在改善退伍军人健康和生活质量的退伍军人事务部研究的步伐。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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CHRISTOPHER P CARDOZO其他文献
CHRISTOPHER P CARDOZO的其他文献
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{{ truncateString('CHRISTOPHER P CARDOZO', 18)}}的其他基金
Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI
Romosozumab 可改善慢性 SCI 患者的骨矿物质密度和结构
- 批准号:
10418624 - 财政年份:2020
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ShEEP 请求建立代谢和行为表型系统
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9795306 - 财政年份:2019
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[ShEEP/LAMb] Request for a Seahorse Extracellular Flux Analyzer
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9209599 - 财政年份:2016
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8424827 - 财政年份:2012
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Notch and Wnt signaling in protection by nandrolone against disuse atrophy
Notch 和 Wnt 信号传导在诺龙防止废用性萎缩中的保护作用
- 批准号:
8840070 - 财政年份:2012
- 资助金额:
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Attenuation of denervation atrophy by nandrolone: molecular mechanisms
诺龙减轻去神经萎缩:分子机制
- 批准号:
7750432 - 财政年份:2009
- 资助金额:
-- - 项目类别:
Attenuation of denervation atrophy by nandrolone: molecular mechanisms
诺龙减轻去神经萎缩:分子机制
- 批准号:
8837614 - 财政年份:2009
- 资助金额:
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