Dual Sensory Loss: Impact of Vision and Hearing Impairment on Spatial Localization

1项目概要/摘要 2.双重感觉丧失（DSL）是视觉和听觉丧失的共同发生。DSL的流行率上升 3随着年龄的增长而急剧上升，预计随着美国人口老龄化而增加。DSL患者增加了 4.日常运作困难，因为许多现实生活中的任务需要视觉和听觉。尽管进行了广泛 5.视力和听力损失的康复分别受到重视， DSL用户面临的6个具体挑战。候选人的长期目标是提高生活质量， 7通过优化其残余视力和听力的利用，使DSL患者独立。当前 8研究重点是他们的空间定位。空间定位是指确定声音的方向， 9视觉对象在环境中，它是重要的安全流动性和有效的社会交往。 10在K99阶段，考生的目标是调查视力和听力缺陷的影响， 11单独和组合，对空间定位的人与DSL，并建立一个空间 12“视野”测量来表征这些影响。在受控实验室环境中（目标1），候选人计划 13以测量具有DSL的受试者在视觉、听觉和视听视觉中的每一个中的定位视野。 14个条件然后，候选人将在两个模拟现实生活任务中测量受试者的定位能力（目标2）： 15定位一辆即将在停车场移动的汽车，并理解一群人中的扬声器。 16目标1中的调查结果将在目标2中与生态有关的流动性和社会背景下得到验证。 17在R 00阶段，候选人的目标是开发和评估可以提高 18人的空间定位能力与DSL。候选人提出培训计划需要量身定制 19基于对个体空间定位能力的评估。提出了一种再校准训练方法 20的目的是重新建立一致的视觉和听觉空间感知，并促进视听 21组合，最大限度地利用残余视力和听力。 22 K99阶段将在明尼苏达大学进行，候选人将在那里接受联合指导 戈登·莱格博士专门研究低视力，佩吉·纳尔逊博士专门研究听力损失。 24研究，以及专门从事计算视觉科学的Dan Kersten博士。候选人还将获得 25优秀的意见，在听觉知觉博士安德鲁Oxenham，在眼科博士埃里克货车Kuijk和 26岁的听力学博士伊芙琳·戴维斯·维恩。培训计划旨在扩展候选人的知识， 27翻译视觉和听觉科学，多感官建模技术，视觉病理学和 28听力障碍，以及评估和康复的当代策略。通过成功的训练， 候选人将独立进行R 00阶段的研究。候选人的职业目标是领导一个 30研究小组，以提高生活质量和独立的人与DSL。

1 Project Summary/Abstract 2 Dual Sensory Loss (DSL) is the co-occurrence of vision and hearing loss. The prevalence of DSL rises 3 steeply with age and is expected to increase as the American population ages. People with DSL have increased 4 difficulties in daily functioning, because many real-life tasks require both vision and hearing. Despite extensive 5 attention to the rehabilitation for vision and hearing loss separately, very little attention has been paid to the 6 specific challenges faced by people with DSL. The candidate’s long term goal is to improve the quality of life and 7 independence of people with DSL by optimizing the utilization of their residual vision and hearing. The current 8 study focuses on their spatial localization. Spatial localization refers to determining the direction of sounds and 9 visual objects in the environment, and it is important for safe mobility and effective social interaction. 10 In the K99 phase, the candidate’s goal is to investigate the impacts of vision and hearing deficits, both 11 individually and in combination, on the spatial localization of people with DSL, and to establish a spatial 12 “perimetry” measure to characterize these effects. In a controlled laboratory context (Aim 1), the candidate plans 13 to measure the localization perimetry of subjects with DSL, in each of the visual, auditory, and audiovisual 14 conditions. The candidate will then measure subjects’ localization ability in two simulated real-life tasks (Aim 2): 15 localizing a car that is about to move in a parking lot and understanding a speaker among a group of people. 16 The findings in Aim 1 will be verified in these ecologically relevant mobility and social contexts in Aim 2. 17 In the R00 phase, the candidate’s goal is to develop and evaluate training methods that can improve the 18 spatial localization ability of people with DSL. The candidate proposes that a training plan needs to be tailored 19 based on the evaluation of the individual’s spatial localization ability. A recalibration training method is developed 20 with the purposes of re-establishing congruent visual and auditory space perception, and facilitating audiovisual 21 combination to maximize the use of residual vision and hearing. 22 The K99 phase will take place in the University of Minnesota, where the candidate will be jointly mentored 23 by Dr. Gordon Legge who specializes in low-vision research, Dr. Peggy Nelson who specializes in hearing-loss 24 research, and Dr. Dan Kersten who specializes in computational vision science. The candidate will also receive 25 excellent advice in auditory perception from Dr. Andrew Oxenham, in ophthalmology from Dr. Erik van Kuijk and 26 in audiology from Dr. Evelyn Davies-Venn. The training plan is to extend the candidate’s knowledge in 27 translational vision and hearing science, the techniques of multisensory modelling, the pathology of vision and 28 hearing impairment, and the contemporary strategies of assessment and rehabilitation. With successful training, 29 the candidate will independently conduct the studies in the R00 phase. The candidate’s career goal is to lead a 30 research team to improve the life quality and independence of people with DSL.