Johns Hopkins O'Brien Center to Advance Kidney Health Equity

约翰霍普金斯奥布莱恩中心致力于促进肾脏健康公平

• 批准号: 10747703
• 负责人: DEIDRA CANDICE CREWS
• 金额: $ 85.78万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10747703
• 关键词: Address; Advisory Committees; Basic Science; Behavior Therapy; Biometry; Brain; Calibration; Clinical; Clinical Research; Clinical Sciences; Cohort Studies; Collaborations; Communities; Consultations; Diet; Dietary Assessment; Discipline; Discrimination; Disparity; Disparity population; Education; Ensure; Equation; Ethnic Origin; Fostering; Gender; Germ-Free; Goals; Health; Health Food; Health Promotion; Housing; Incubators; Inequity; Infrastructure; Intervention; Intervention Studies; Joints; Kidney; Kidney Diseases; Laboratories; Lead; Mus; Nephrology; Periodicals; Phenotype; Population Heterogeneity; Prevention Research; Proteomics; Protocols documentation; Quality Control; Race; Recommendation; Research; Research Design; Research Personnel; Resource Development; Resources; Risk; Services; Sex Differences; Societies; Socioeconomic Status; Stress; Structural Racism; Students; System; Translations; Validation; biomedical resource; burden of illness; career; dietary; epidemiology study; experience; gut microbiota; health disparity; health equity; health inequalities; humanized mouse; innovation; marginalization; marginalized community; marginalized population; microbiome; novel; outreach; population health; pre-clinical; pre-clinical research; programs; social; social disparities; social health determinants; social stressor; socioeconomics; summer student; tool; translational scientist

OVERALL ABSTRACT Disparities in kidney health are profound; and for decades, have been documented for socially marginalized populations, yet little progress has been made to mitigate them. The overarching goal of the Johns Hopkins O’Brien Center to Advance Kidney Health Equity (JHOC) is to harness the collective expertise of basic, clinical and translational researchers at Johns Hopkins to serve as a national resource for investigators addressing the fundamental question of: what are the underlying mechanisms responsible for profound disparities in kidney health and how can they be mitigated? We will leverage the strengths and existing infrastructure of the Johns Hopkins Division of Nephrology, the Welch Center for Prevention, Epidemiology and Clinical Research and the Johns Hopkins Center for Health Equity. JHOC will include; 3 integrated cores (Administrative, Biomedical Resource and Resource Development); an Executive Committee; an Internal Advisory Committee, and a Community Advisory Board. Together, we will (1) provide an innovative portfolio of research services, resources, and tools for investigators to understand and ameliorate disparities in kidney disease; (2) develop new and refine existing resources as part of a dynamic incubator space for the conduct of basic and clinical research relevant to advancing kidney health equity; (3) transfer mature resources to the Biomedical Resource Core to be shared with the community; (4) plan and execute an annual Summer Student Enrichment Program which leverages a long-standing partnership with a Johns Hopkins program for students from socioeconomically under-resourced backgrounds; (5) foster the careers of early-stage investigators by promoting trans-disciplinary and cross-sector collaboration that will attract investigators from fields not traditionally involved in kidney health equity research; and (6) collaborate with the National Coordinating Center to prioritize external requests for resources and enhance national outreach. JHOC will support investigators conducting pre-clinical (basic), clinical or population health research addressing kidney health disparities, and will make recommendations to inform strategies, interventions, and approaches aimed at achieving kidney health equity.

整体 摘要 肾脏健康的差异是深刻的;几十年来，已被记录为社会边缘化 这些问题在人口中普遍存在，但在缓解这些问题方面几乎没有取得进展。约翰霍普金斯的首要目标 奥布莱恩中心促进肾脏健康公平（JHOC）是利用集体的专业知识，基础，临床 和约翰霍普金斯的翻译研究人员，作为一个国家资源的研究人员解决 基本问题：造成肾功能严重差异的潜在机制是什么？ 健康问题，如何缓解？我们将利用约翰的优势和现有基础设施 霍普金斯肾脏病学分部、韦尔奇预防、流行病学和临床研究中心和 约翰霍普金斯健康公平中心。JHOC将包括：3个集成核心（行政、生物医学 资源和资源开发）;执行委员会;内部咨询委员会，以及 社区咨询委员会。我们将共同（1）提供创新的研究服务组合， 资源和工具，供研究人员了解和改善肾脏疾病的差异;（2）开发 新的和完善现有的资源，作为一个动态的孵化器空间的一部分，进行基础和临床 与促进肾脏健康公平相关的研究;（3）将成熟的资源转移到生物医学资源 与社区分享核心内容;（4）计划并执行年度暑期学生充实计划 它利用了与约翰霍普金斯大学的长期合作伙伴关系， 社会经济上资源不足的背景;（5）通过以下方式促进早期调查人员的职业生涯 促进跨学科和跨部门合作，吸引来自外地的调查人员， 传统上参与肾脏健康公平研究;（6）与国家协调委员会合作 中心优先考虑外部资源请求并加强国家外联。JHOC将支持 开展针对肾脏健康的临床前（基础）、临床或人群健康研究的研究者 差距，并将提出建议，为战略，干预措施和方法提供信息， 实现肾脏健康公平。