Stanford PRIHSM: PReventing Inequities in Hemorrhage-related Severe Maternal Morbidity
斯坦福大学 PRIHSM:预防与出血相关的严重孕产妇发病率的不平等
基本信息
- 批准号:10748636
- 负责人:
- 金额:$ 212万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-08-17 至 2030-07-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAdmission activityAffectAnemiaAsianAsian populationAttentionBirthBlack PopulationsBlack raceCaliforniaCaringCenters of Research ExcellenceCesarean sectionClinicalCollaborationsCommunitiesComplexDiagnosisDimensionsDisciplineDiscipline of obstetricsDisparityEmotionalEnvironmentEquityEthnic OriginEvaluationGoalsHealthcareHemorrhageHigh PrevalenceHospitalizationHospitalsIncidenceIndividualInequityInterventionIron deficiency anemiaLatinxLatinx populationLeadershipLife Cycle StagesLinkLocationMaternal HealthMaternal MortalityMaternal health equityMental HealthMethodsMorbidity - disease rateMothersNative AmericansOutcomePatientsPersonsPlayPopulationPopulation HeterogeneityPositioning AttributePost-Traumatic Stress DisordersPostpartum DepressionPostpartum HemorrhagePostpartum PeriodPregnancyPrevalencePreventionPrevention strategyProviderRaceResearchResearch InfrastructureRestRiskRisk FactorsRoleScienceStandardizationTrainingTranslatingUniversitiesWorkantenatalcommunity involvementdisparity eliminationdisparity reductioneffective therapyethnic disparityexperiencehealth equityhigh riskimprovedinnovationintrapartummarginalized populationmortalitymultidisciplinarypost-traumatic stresspost-traumatic symptomspostpartum healthpreventprospectiveracial disparitysevere maternal morbiditysocialsocial structuretraining opportunitytreatment strategyunderserved area
项目摘要
Project Summary: Overall
Postpartum hemorrhage (PPH) is a leading cause of maternal death and severe maternal morbidity (SMM) and disproportionately affects socially marginalized groups. We propose to create a Maternal Health Research Center of Excellence at Stanford University called PRIHSM (PReventing Inequities in Hemorrhage-related Severe Maternal morbidity). The goals of PRIHSM are to reduce PPH and associated SMM by reducing and addressing disparities in important precursors to PPH-related SMM and mortality: cesarean birth and iron deficiency anemia (IDA). The problem of maternal IDA is vastly under-appreciated yet it affects approximately 16% of pregnancies in the U.S.; rates are 3-4x higher among Black people and 1.5-2x higher among Latinx people compared to the rest of the population. This translates to higher rates of PPH-related SMM. We propose that by effectively addressing antenatal IDA and these disparities, we can reduce PPH-related SMM. Additionally, almost 1 in 3 U.S. births are by cesarean delivery, rates vary 10-fold across hospitals, and Black and Asian individuals have the highest prevalence of cesarean section among low-risk pregnancies. While cesarean section can be a lifesaving intervention when appropriate, it is associated with significant risks that include PPH. We propose that enhanced birth equity and reduced variability in obstetric management are important strategies in addressing disparities in cesarean-linked PPH and reducing PPH-related SMM. Thus, our Aims are to: Aim 1 (Project 1). Reduce antenatal IDA by developing, implementing, and disseminating a patient-informed Anemia Prevention Toolkit, which will standardize the evaluation, diagnosis, and treatment of IDA and reduce the prevalence of IDA and racial/ethnic disparities in IDA at birth admission and PPH-associated SMM. Aim 2 (Project 2). Reduce disparities in rates of primary cesarean birth and cesarean-linked PPH by conducting a mixed methods study to understand drivers of hospital-level disparities in these outcomes, and implementing a patient-informed Maternal Equity Guide. Our work will involve community-university partnerships focused on improving maternal health equity and be driven by perspectives of patients, providers, and healthcare leadership. Our work will provide training opportunities to build research and clinical expertise relevant to PPH, especially among individuals who represent diverse perspectives and experiences within academic and community-based settings, and underserved areas. We propose a bold yet achievable agenda that will affect a sustainable decline in PPH-related mortality and morbidity and disparities.
项目摘要:总体
产后出血(PPH)是孕产妇死亡和严重的孕产妇发病率(SMM)的主要原因,并且不成比例地影响社会边缘化的群体。我们建议在斯坦福大学创建一个名为Prihsm的孕产妇健康研究中心(防止与出血有关的严重母亲发病率)。 PRIHSM的目标是通过减少与PPH相关的SMM和死亡率的重要前体的差异和解决差异来减少PPH和SMM:剖宫产和铁缺乏症贫血(IDA)。孕产妇的问题被大大低估了,但在美国大约影响了16%的怀孕。与其他人口相比,黑人的率高于黑人3-4倍,拉丁人的率高于1.5-2倍。这意味着与PPH相关的SMM率较高。我们建议,通过有效解决产前IDA和这些差异,我们可以减少与PPH相关的SMM。此外,美国三分之一的出生是通过剖宫产分娩的,在医院的占10倍,黑人和亚洲人在低风险妊娠中的剖宫产患病率最高。虽然剖宫产部分可能是适当的救生干预措施,但它与包括PPH在内的重大风险有关。我们建议,增强的出生权益和产科管理的变异性降低是解决剖宫产链接PPH差异并减少与PPH相关的SMM的重要策略。因此,我们的目标是:目标1(项目1)。通过开发,实施和传播预防患者的贫血预防工具包来减少产前IDA,这将标准化IDA的评估,诊断和治疗,并降低出生录取和PPH相关SMM时IDA的IDA和IDA和种族/族裔差异的流行。 AIM 2(项目2)。通过进行混合方法研究,以了解这些结果中医院水平差异的驱动因素,并实施患者知识的母性股权指南,从而减少原发性剖宫产和剖宫产与PPH的差异。我们的工作将涉及致力于改善孕产妇健康公平的社区 - 大学伙伴关系,并由患者,提供者和医疗保健领导者的观点驱动。我们的工作将提供培训机会,以建立与PPH相关的研究和临床专业知识,尤其是在代表学术和社区环境以及服务不足领域的各种观点和经验的个人中。我们提出了一个大胆而可实现的议程,该议程将影响与PPH相关的死亡率,发病率和差异的可持续下降。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
SUZAN L CARMICHAEL其他文献
SUZAN L CARMICHAEL的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('SUZAN L CARMICHAEL', 18)}}的其他基金
Building a causal pathway framework to identify interventions to eliminate racial/ethnic disparities in severe maternal morbidity
建立因果路径框架,以确定消除严重孕产妇发病率方面的种族/民族差异的干预措施
- 批准号:
10684599 - 财政年份:2022
- 资助金额:
$ 212万 - 项目类别:
Building a causal pathway framework to identify interventions to eliminate racial/ethnic disparities in severe maternal morbidity
建立因果路径框架,以确定消除严重孕产妇发病率方面的种族/民族差异的干预措施
- 批准号:
10656523 - 财政年份:2021
- 资助金额:
$ 212万 - 项目类别:
Building a causal pathway framework to identify interventions to eliminate racial/ethnic disparities in severe maternal morbidity
建立因果路径框架,以确定消除严重孕产妇发病率方面的种族/民族差异的干预措施
- 批准号:
10280836 - 财政年份:2021
- 资助金额:
$ 212万 - 项目类别:
Building a causal pathway framework to identify interventions to eliminate racial/ethnic disparities in severe maternal morbidity
建立因果路径框架,以确定消除严重孕产妇发病率方面的种族/民族差异的干预措施
- 批准号:
10878197 - 财政年份:2021
- 资助金额:
$ 212万 - 项目类别:
Building a causal pathway framework to identify interventions to eliminate racial/ethnic disparities in severe maternal morbidity
建立因果路径框架,以确定消除严重孕产妇发病率方面的种族/民族差异的干预措施
- 批准号:
10490296 - 财政年份:2021
- 资助金额:
$ 212万 - 项目类别:
Severe Maternal Morbidity: An Investigation of Racial-Ethnic Disparities, Social Disadvantage & Maternal Weight
严重的孕产妇发病率:对种族差异、社会弱势的调查
- 批准号:
10660008 - 财政年份:2018
- 资助金额:
$ 212万 - 项目类别:
Severe Maternal Morbidity: An Investigation of Racial-Ethnic Disparities, Social Disadvantage & Maternal Weight
严重的孕产妇发病率:对种族差异、社会弱势的调查
- 批准号:
10087967 - 财政年份:2018
- 资助金额:
$ 212万 - 项目类别:
Severe Maternal Morbidity: An Investigation of Racial-Ethnic Disparities, Social Disadvantage & Maternal Weight
严重的孕产妇发病率:对种族差异、社会弱势的调查
- 批准号:
10300988 - 财政年份:2018
- 资助金额:
$ 212万 - 项目类别:
Severe Maternal Morbidity: An Investigation of Racial-Ethnic Disparities, Social Disadvantage & Maternal Weight
严重的孕产妇发病率:对种族差异、社会弱势的调查
- 批准号:
10091301 - 财政年份:2018
- 资助金额:
$ 212万 - 项目类别:
相似海外基金
Differences in Hospital Nursing Resources among Black-Serving Hospitals as a Driver of Patient Outcomes Disparities
黑人服务医院之间医院护理资源的差异是患者结果差异的驱动因素
- 批准号:
10633905 - 财政年份:2023
- 资助金额:
$ 212万 - 项目类别:
Developing and evaluating new measures of family availability to provide care to people with dementia
制定和评估家庭可用性的新衡量标准,为痴呆症患者提供护理
- 批准号:
10728725 - 财政年份:2023
- 资助金额:
$ 212万 - 项目类别:
Impact of Autonomic Dysfunction on Multi-Organ Dysfunction following Severe TBI: The AUTO-BOOST Study
严重 TBI 后自主神经功能障碍对多器官功能障碍的影响:AUTO-BOOST 研究
- 批准号:
10607731 - 财政年份:2023
- 资助金额:
$ 212万 - 项目类别:
Driving Rehabilitation and Innovation for Evaluating Risk in Post-Intensive Care Unit Survivors (DRIVE-PICS)
推动康复和创新以评估重症监护室幸存者的风险 (DRIVE-PICS)
- 批准号:
10574692 - 财政年份:2023
- 资助金额:
$ 212万 - 项目类别:
Substance use treatment and county incarceration: Reducing inequities in substance use treatment need, availability, use, and outcomes
药物滥用治疗和县监禁:减少药物滥用治疗需求、可用性、使用和结果方面的不平等
- 批准号:
10585508 - 财政年份:2023
- 资助金额:
$ 212万 - 项目类别: