Wearable Microsystem for Continuous Personalized Aerosol Exposure Assessment
用于连续个性化气溶胶暴露评估的可穿戴微系统
基本信息
- 批准号:10747130
- 负责人:
- 金额:$ 3.26万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-04-05 至 2023-06-30
- 项目状态:已结题
- 来源:
- 关键词:AerosolsAirAir PollutantsAir PollutionAirborne Particulate MatterBiologicalCarbonCessation of lifeChemicalsClassificationCommunitiesCommunity Health SystemsComplexDataData SetDevelopmentDevicesDiameterElementsEnvironmentEnvironmental HealthEvaluationExposure toFractionationGoalsGrantHealthHeterogeneityHumidityIndividualInfrastructureInterventionLife StyleLinkLiquid substanceLocationMeasuresMethodsMicrofluidic MicrochipsMicrofluidicsModelingMonitorNatureParticulateParticulate MatterPhasePollutionPublic HealthPublic Health Applications ResearchReal-Time SystemsReportingResearchResolutionRiskSamplingSpatial DistributionSurfaceSystemTechniquesTechnologyTemperatureTimeTrace ElementsTrace metalUltrafineair monitoringassessment applicationatmospheric aerosolscommunity health studycostcost effectivedesigneffective interventionevaluation/testingfield studyfine particleshealth datahealth disparity populationshealth managementimprovedinnovationmicroelectronicsmicrosystemsminiaturizeminiaturized devicemortalitynovelparticleparticle counterpathogenpollutantportabilitypublic health interventionsoftware developmentspatiotemporaltemporal measurementtoolultrafine particleurban areawearable device
项目摘要
Project Summary / Abstract
Exposure to air pollution consistently ranks among the leading global causes of illness and death, a majority of
which can be attributed to airborne particulate matter (PM) pollution. The lack of effective interventions are due
in large part to our inability to properly characterize and quantify air pollutants with the spatial and temporal
resolution that represents personal exposures. Most existing tools for monitoring air pollution are incapable of
accurately measuring exposures to multiple pollutants or the variability of pollutant chemical composition within
and across individual microenvironments, time of day, personal lifestyles, etc. The long term goal of our team is
to establish an infrastructure for real-time, continuous, multi-pollutant, air quality monitoring with very high spatial
and temporal resolution, enabling groundbreaking environmental health research leading to effective,
personalized, exposure analytics and interventions to ultimately reduce exposures to air pollutants and improve
overall public health. In Phase 1 of this effort, we have developed wearable technologies for continuous gaseous
air pollutant monitoring under an ongoing grant. Herein, we propose Phase 2 development of wearable
technologies for continuous airborne particulate monitoring. The objective of this renewal application is to
develop a wearable system that can, in real time, quantify size-fractionated PM across two orders of
hydrodynamic diameter (~2.5µm to 50nm) and classify health-critical elemental components of PM, trace metals
and elemental carbon. This cost effective system could be distributed over a network of users, gathering real-
time data while mobile in the environment, over a wide spatial distribution, with high spatial and temporal
resolution. Moreover, by time tagging this data with environmental (temperature, humidity, etc.) and physical
(location, activity, etc.) parameters, our system would permit an unprecedentedly information rich dataset for
offline analysis and health impact modeling, as well as for personal exposure management at the individual user
level. The Specific Aims of this project are to: 1) Develop and characterize a miniaturized system for real-time
PM capture and size fractionation (accomplished by development of a miniaturized component to capture
airborne PM in a liquid, followed by a microfluidic component that separates the PM into five size bins); 2)
Develop and characterize a miniaturized system for real-time PM quantification and elemental component
classification (accomplished by capacitively counting particles within each size bin followed by electrochemical
classification of trace metal and elemental carbon components); and 3) Evaluate the new PM monitoring system
for community health studies in real world environments (accomplished by field testing and evaluation against
stationary federal reference methods for PM mass and chemical composition, followed by a community exposure
assessment study to characterize the spatial and temporal heterogeneity of air pollutants across disparate
communities of health burden and risk within the Detroit urban area).
项目摘要/摘要
项目成果
期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype.
- DOI:10.1186/gb-2008-9-6-r100
- 发表时间:2008
- 期刊:
- 影响因子:12.3
- 作者:Lobenhofer, Edward K.;Auman, J. Todd;Blackshear, Pamela E.;Boorman, Gary A.;Bushel, Pierre R.;Cunningham, Michael L.;Fostel, Jennifer M.;Gerrish, Kevin;Heinloth, Alexandra N.;Irwin, Richard D.;Malarkey, David E.;Merrick, B. Alex;Sieber, Stella O.;Tucker, Charles J.;Ward, Sandra M.;Wilson, Ralph E.;Hurban, Patrick;Tennant, Raymond W.;Paules, Richard S.
- 通讯作者:Paules, Richard S.
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Joseph Timothy Dvonch其他文献
Joseph Timothy Dvonch的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Joseph Timothy Dvonch', 18)}}的其他基金
Wearable Microsystem for Continuous Personalized Aerosol Exposure Assessment
用于连续个性化气溶胶暴露评估的可穿戴微系统
- 批准号:
10316689 - 财政年份:2021
- 资助金额:
$ 3.26万 - 项目类别:
Wearable Microsystem for Continuous Personalized Aerosol Exposure Assessment
用于连续个性化气溶胶暴露评估的可穿戴微系统
- 批准号:
10491288 - 财政年份:2021
- 资助金额:
$ 3.26万 - 项目类别:
Wearable Microsystem for Continuous Personalized Aerosol Exposure Assessment
用于连续个性化气溶胶暴露评估的可穿戴微系统
- 批准号:
10683214 - 财政年份:2021
- 资助金额:
$ 3.26万 - 项目类别:
相似国自然基金
湍流和化学交互作用对H2-Air-H2O微混燃烧中NO生成的影响研究
- 批准号:51976048
- 批准年份:2019
- 资助金额:61.0 万元
- 项目类别:面上项目
相似海外基金
How are plants responding to damage by oxidizing air pollutants?
植物如何应对氧化空气污染物造成的损害?
- 批准号:
DP230100296 - 财政年份:2023
- 资助金额:
$ 3.26万 - 项目类别:
Discovery Projects
Unified assessment of health effects of multiple air pollutants inducing reactive oxygen species production
统一评估多种引起活性氧产生的空气污染物的健康影响
- 批准号:
22KJ0372 - 财政年份:2023
- 资助金额:
$ 3.26万 - 项目类别:
Grant-in-Aid for JSPS Fellows
Air pollutants, heat exposure, and kidney health: A longitudinal study in women in Central America
空气污染物、热暴露和肾脏健康:针对中美洲女性的纵向研究
- 批准号:
10583301 - 财政年份:2023
- 资助金额:
$ 3.26万 - 项目类别:
Prenatal Traffic-Related Air Pollutants, Placental Epitranscriptomics, and Child Cognition
产前交通相关空气污染物、胎盘表观转录组学和儿童认知
- 批准号:
10366988 - 财政年份:2022
- 资助金额:
$ 3.26万 - 项目类别:
Analysis of the protective effect of metallothioneins against lung injury caused by air pollutants.
金属硫蛋白对空气污染物所致肺损伤的保护作用分析
- 批准号:
22K06588 - 财政年份:2022
- 资助金额:
$ 3.26万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Disrupting Noxious Synergies of Indoor Air Pollutants and their Impact in Childhood Health and Wellbeing, using Advanced Intelligent Multisensing and Green Interventions
利用先进的智能多传感和绿色干预措施,破坏室内空气污染物的有害协同作用及其对儿童健康和福祉的影响
- 批准号:
10051924 - 财政年份:2022
- 资助金额:
$ 3.26万 - 项目类别:
EU-Funded
Development and/or evaluation of emission factors for Odour, air pollutants, greenhouse gas emissions and air quality impact assessment for industrial and municipal sources in cold region
寒冷地区工业和市政源恶臭、空气污染物、温室气体排放排放因子的制定和/或评价以及空气质量影响评价
- 批准号:
RGPIN-2019-07299 - 财政年份:2022
- 资助金额:
$ 3.26万 - 项目类别:
Discovery Grants Program - Individual
Exposure to Ambient Air Pollutants, Circulating microRNAs, and Hepatic Fat Fraction Among Young Adults
年轻人接触环境空气污染物、循环 microRNA 和肝脂肪分数
- 批准号:
10537895 - 财政年份:2022
- 资助金额:
$ 3.26万 - 项目类别:
Novel Approaches for Improving Inflammation Resolution Following Chronic Exposure to Air Pollutants
改善长期接触空气污染物后炎症消退的新方法
- 批准号:
10348421 - 财政年份:2022
- 资助金额:
$ 3.26万 - 项目类别:
Prenatal Traffic-Related Air Pollutants, Placental Epitranscriptomics, and Child Cognition
产前交通相关空气污染物、胎盘表观转录组学和儿童认知
- 批准号:
10589926 - 财政年份:2022
- 资助金额:
$ 3.26万 - 项目类别: