Neural basis of Braille literacy in blind adults and children
盲人成人和儿童盲文识字的神经基础
基本信息
- 批准号:10748068
- 负责人:
- 金额:$ 9.57万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-03-01 至 2027-02-28
- 项目状态:未结题
- 来源:
- 关键词:AdultAwardBachelor&aposs DegreeBehavioralBlindnessBrainChildCognitiveDataDissociationDoctor of PhilosophyFunctional Magnetic Resonance ImagingGoalsGrantIndividualLaboratoriesLanguageLearningLinguisticsManuscriptsMaster of ScienceMentorsNational Research Service AwardsNeurosciencesOrthographyPaperParentsParietalPersonsPhysiciansPreparationPublicationsPublishingReadingResearchRoleSeriesSystemTactileTalentsTestingTrainingTraining ProgramsUniversitiesWorkbehavior testblindbraillecareercognitive neurosciencecognitive testingdesignexperienceexperimental studyliteracyneuralparent grantprogramsskillsstudent trainingtheories
项目摘要
PROJECT SUMMARY
The proposed diversity supplement application is intended to support Ms. Zaida McClinton in her training as a
cognitive neuroscientist investigating brain plasticity. Ms. McClinton is a highly talented and well-trained
student completing her undergraduate degree in Neuroscience at Johns Hopkins University. The proposed
supplement will support her in obtaining a master’s in Neuroscience and conducting a year-and-a-half of
mentored research in my laboratory working on the neural basis of Braille reading in congenitally blind adults.
I will mentor Ms. McClinton while she designs, carries out, analyzes, presents and publishes this neuroscience
work on Braille reading. The grant will support her as she acquires critical skills in cognitive neuroscience,
including fMRI analysis and TMS, and give her the edge she needs to enter a high-quality MD-PhD program
and provide preliminary data for an NRSA F30 application. During the proposed supplement Ms. McClinton
will conduct a series of studies that build on and are complementary to the parent award but are not redundant
with it. Ms. McClinton will use the already collected fMRI data to conduct fMRI-guided TMS studies that test
the cognitive and behavioral contributions of the posterior parietal (PPC) and ventral occipito-temporal
(vOTC) cortical circuits to Braille reading. The goals of the parent award are to discover whether people who
are born blind develop ‘tactile word form’ representations in the PPC and to test the role of the vOTC in
Braille reading for blind adults and compare its contribution to that of the PPC. Ms. McClinton will first test
the behavioral relevance of the PPC and vOTC to reading using fMRI guided TMS, which has never been done
before. Next, she will test the timing of the contribution of these regions. We hypothesize that PPC performs
form-based orthographic processing, and is therefore involved earlier, whereas vOTC performs more high-
level language functions and is therefore involved later. These experiments are highly complementary to the
goals of the parent award, which will dissociate the contributions of these regions to Braille reading. Finally,
closing the loop and answering the question of why the vOTC is active during Braille reading, Ms. McClinton
will test whether vOTC is relevant to high-level linguistic processing in blindness. The proposed work is
highly theoretically significant and complementary to the parent proposal since TMS gives us an opportunity to
test behavioral relevance of activation observed with fMRI and to thus inform theories of Braille reading and
plasticity in blindness. We anticipate that the proposed experiments will lead to 3 or 4 first author publications
providing an intensive manuscript preparation experience. This opportunity will enable Ms. McClinton to
learn cutting edge cognitive neuroscience skills and propel her into a career as a cognitive physician-
neuroscientist investigating brain plasticity.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Marina Bedny其他文献
Marina Bedny的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Marina Bedny', 18)}}的其他基金
Neural basis of Braille literacy in blind adults and children
盲人成人和儿童盲文识字的神经基础
- 批准号:
10574513 - 财政年份:2022
- 资助金额:
$ 9.57万 - 项目类别:
Neural basis of Braille literacy in blind adults and children
盲人成人和儿童盲文识字的神经基础
- 批准号:
10342354 - 财政年份:2022
- 资助金额:
$ 9.57万 - 项目类别:
Visual cortex plasticity in blindness: a window into flexibility of human cortex
失明时的视觉皮层可塑性:了解人类皮层灵活性的窗口
- 批准号:
10203995 - 财政年份:2017
- 资助金额:
$ 9.57万 - 项目类别:
Visual cortex plasticity in blindness: a window into flexibility of human cortex
失明时的视觉皮层可塑性:了解人类皮层灵活性的窗口
- 批准号:
10016300 - 财政年份:2017
- 资助金额:
$ 9.57万 - 项目类别:
相似海外基金
Open Access Block Award 2024 - Durham University
2024 年开放访问区块奖 - 杜伦大学
- 批准号:
EP/Z531480/1 - 财政年份:2024
- 资助金额:
$ 9.57万 - 项目类别:
Research Grant
Open Access Block Award 2024 - Goldsmiths College
2024 年开放获取区块奖 - 金史密斯学院
- 批准号:
EP/Z531509/1 - 财政年份:2024
- 资助金额:
$ 9.57万 - 项目类别:
Research Grant
Open Access Block Award 2024 - John Innes Centre
2024 年开放访问区块奖 - 约翰·英尼斯中心
- 批准号:
EP/Z53156X/1 - 财政年份:2024
- 资助金额:
$ 9.57万 - 项目类别:
Research Grant
Open Access Block Award 2024 - London School of Economics & Pol Sci
2024 年开放获取区块奖 - 伦敦政治经济学院
- 批准号:
EP/Z531625/1 - 财政年份:2024
- 资助金额:
$ 9.57万 - 项目类别:
Research Grant
Open Access Block Award 2024 - Oxford Brookes University
2024 年开放获取区块奖 - 牛津布鲁克斯大学
- 批准号:
EP/Z531728/1 - 财政年份:2024
- 资助金额:
$ 9.57万 - 项目类别:
Research Grant
Open Access Block Award 2024 - The Francis Crick Institute
2024 年开放获取区块奖 - 弗朗西斯·克里克研究所
- 批准号:
EP/Z531844/1 - 财政年份:2024
- 资助金额:
$ 9.57万 - 项目类别:
Research Grant
Open Access Block Award 2024 - The Natural History Museum
2024 年开放访问区块奖 - 自然历史博物馆
- 批准号:
EP/Z531856/1 - 财政年份:2024
- 资助金额:
$ 9.57万 - 项目类别:
Research Grant
Open Access Block Award 2024 - University of Brighton
2024 年开放获取区块奖 - 布莱顿大学
- 批准号:
EP/Z531935/1 - 财政年份:2024
- 资助金额:
$ 9.57万 - 项目类别:
Research Grant
Open Access Block Award 2024 - University of Bristol
2024 年开放获取区块奖 - 布里斯托大学
- 批准号:
EP/Z531947/1 - 财政年份:2024
- 资助金额:
$ 9.57万 - 项目类别:
Research Grant
Open Access Block Award 2024 - University of Bradford
2024 年开放获取区块奖 - 布拉德福德大学
- 批准号:
EP/Z531923/1 - 财政年份:2024
- 资助金额:
$ 9.57万 - 项目类别:
Research Grant














{{item.name}}会员




