The University of North Carolina-Kinshasa School of Public Health Research Partnership in the Democratic Republic of Congo; a Model for Improving Women's and Children's Health Through Research

摘要 刚果(金)是世界第五大最贫困国家， 相应地，刚果民主共和国的妇女和儿童的健康状况也很差。在刚果民主共和国，母亲 死亡率是联合国可持续发展目标(SDG)设定的目标的六倍， 新生儿死亡率是SDG的两倍多。像刚果民主共和国这样的低收入国家贡献了 与孕产妇和新生儿死亡率不成比例，但往往没有出现在临床研究中。这个 金沙萨公共卫生学院(KSPH)和北卡罗来纳大学(UNC)一直在研究 自2005年以来一直是合作伙伴，共同的使命是改善低收入国家的妇幼保健 通过研究可持续、成本效益高的卫生干预措施。我们的伙伴关系包括15个以上 在尤尼斯·肯尼迪·施莱弗NICHD全球妇女和妇女网络中担任研究单位的多年经验 儿童健康研究。我们已经组建了一支拥有战略领域专业知识的多学科团队 孕产妇和新生儿健康，包括妇产科、新生儿科、传染病、热带 医药。我们的团队能够灵活地利用各种研究方法，包括流行病学、临床 试验和实施科学。我们在农村、城市周边和 在刚果(金)的城市社区开展基于社区和设施的临床研究。自2016年以来，我们已经 发表了271篇论文，完成了22项研究，招募了90,390名妇女和62,117名儿童参与研究 学习。KSPH-UNC伙伴关系，由Antoinette Tshefu博士(KSPH；IPI)和Melissa Bauserman领导 (UNC；PI)，并拥有专门知识和资源来解决产妇保健各个领域的研究问题 和儿童健康。我们的总体目标是发现以证据为基础的策略，以改善低成本的健康结果 和中低收入国家。为了实现这一目标，我们将：及早开展高质量的研究 识别怀孕，严格跟踪结果和随访率&90%，支持全球 与创新的试验和试验设计建立网络，加强刚果民主共和国的研究基础设施，并开发 下一代研究带头人。KSPH-UNC伙伴关系处于独特的地位，可以为 全球网络的使命，我们完全承诺通过以下方式继续支持全球网络 协作性研究提案。

ABSTRACT The Democratic Republic of the Congo (DRC) is the fifth most impoverished country in the world, and correspondingly, women and children in the DRC experience poor health outcomes. In the DRC, the maternal mortality rate is six times the target set by the United Nations Sustainable Development Goals (SDG), and the neonatal mortality rate is more than double the SDG. Low-income countries, like the DRC contribute disproportionately to maternal and neonatal mortality but are often not represented in clinical research. The Kinshasa School of Public Health (KSPH) and the University of North Carolina (UNC) have been research partners since 2005, with the shared mission of improving maternal and child health in low-income countries through the research of sustainable, cost-effective health interventions. Our partnership includes more than 15 years of experience as a research unit in the Eunice Kennedy Shriver NICHD Global Network for Women’s and Children’s Health Research. We have assembled a multi-disciplinary team with expertise in strategic areas in maternal and newborn health, including obstetrics and gynecology, neonatology, infectious diseases, tropical medicine. Our team is facile in utilizing a variety of research methodologies, including epidemiology, clinical trials and implementation science. We have built an extensive research infrastructure in rural, peri-urban and urban communities to conduct community and facility-based clinical studies in the DRC. Since 2016, we have published 271 papers, completed 22 studies, and enrolled 90,390 women and 62,117 children in research studies. The KSPH-UNC Partnership, led by Drs. Antoinette Tshefu (KSPH; iPI) and Melissa Bauserman (UNC; PI), and has the expertise and resources to address research questions in a variety of areas of maternal and child health. Our overall goal is to discover evidenced-based strategies to improve health outcomes in low and lower-middle-income countries. To achieve this goal, we will: execute high-quality studies with early identification of pregnancies, rigorous tracking of outcomes and follow-up rates >90%, support the Global Network with innovative trials and trial designs and strengthen research infrastructure in the DRC and develop the next generation of research leaders. The KSPH-UNC Partnership is uniquely positioned to contribute to the mission of the Global Network, and we are fully committed to continued support of the Global Network through collaborative research proposals.