UTRGV Diversity Center for Genome Research

UTRGV 基因组研究多样性中心

• 批准号: 10749783
• 负责人: SARAH A. WILLIAMS-BLANGERO
• 金额: $ 259.14万
• 依托单位: UNIVERSITY OF TEXAS RIO GRANDE VALLEY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-18 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10749783
• 关键词: Address; Anthropology; Area; Bioinformatics; Collaborations; Communities; Community Outreach; Development; Disease; Education; Education and Outreach; Environmental Epidemiology; Environmental Exposure; Equipment; Extramural Activities; Faculty; Family; Fostering; Funding; Future; Genetic; Genome; Genomics; Goals; Growth; Health; Hispanic; Hispanic-serving Institution; Human Genetics; Image; Institution; Interdisciplinary Study; Investigation; Investments; Major Depressive Disorder; Medical; Mexican; Mexican Americans; Molecular Genetics; Neurosciences; Population; Postdoctoral Fellow; Program Development; Program Sustainability; Proteomics; Research; Research Personnel; Research Project Grants; Research Support; Resources; Science; Scientist; Services; Statistical Methods; Strategic Planning; Structure; Students; Techniques; Technology; Texas; Training; United States National Institutes of Health; Universities; Workforce Development; career; career development; community center; community engagement; community organizations; design; disease disparity; environmental chemistry; experience; genetic epidemiology; health disparity; higher education; hispanic community; improved; innovation; instrumentation; interest; literacy; medical schools; minority student; multidisciplinary; non-alcoholic fatty liver disease; novel; programs; recruit; senior faculty; skills; stem cell biology; training opportunity; university student

PROJECT SUMMARY The University of Texas Rio Grande Valley seeks to establish a Diversity Center for Genome Research that will build UTRGV’s genomics research capacity by 1) expanding genomic research capabilities and discoveries in two innovative research projects; and 2) enhancing the size and quality of the available genomics workforce. Leveraging the exciting activities and resources available in the two highly innovative research projects, the Center’s structure and approach are designed to expand the pool of diverse genomic scientists, clinician scientists, and researchers at both the doctoral and technical staff levels who can perform cutting-edge multidisciplinary genomics research. The Center’s Workforce Development Core includes efforts to develop the pipeline of Hispanic pre-college students interested in careers in genetics and genomics so that workforce development programs will expand and become self-sustaining in the future. The Center’s Community Engagement Core is designed to improve genomic literacy in the predominantly Hispanic local population and increase interest in participation in genomic studies. The research in the two multidisciplinary projects to be supported by the Center is focused on diseases that are important health disparities for the local Mexican American population, nonalcoholic fatty liver disease and major depressive disorder. The team science-focused research will be meaningful to our trainees since the diseases under investigation disproportionately impact Mexican American families. The research programs leverage state-of-the-art instrumentation to provide outstanding training opportunities for faculty, students, postdocs, and residents. Cutting-edge technologies are incorporated into the projects, maximizing the impact of training and research experiences. Techniques and approaches used in the projects include bioinformatics, computational genomics, statistical genetics, molecular genetics, genetic epidemiology, genomics, proteomics, exposomics, stem cell biology, novel statistical methods, environmental chemistry, environmental epidemiology, neuroscience, imaging genomics, and medical anthropology. The proposed research areas provide an outstanding range of training opportunities and are rich with potential spin-off projects for junior faculty and senior faculty seeking to branch into genomics. Through the activities of its Administrative Core, Workforce Development Core, Community Engagement Core, and Research Projects, the proposed UTRGV Diversity Center for Genome Research will support cutting-edge genomic research, capacity building, and training in genomics at one of the nation’s largest Hispanic-serving institutions.

项目概要 德克萨斯大学里奥格兰德河谷分校寻求建立一个基因组研究多样性中心，该中心将 通过以下方式建立 UTRGV 的基因组学研究能力： 1) 扩大基因组学研究能力和发现 两个创新研究项目； 2) 提高现有基因组学劳动力的规模和质量。 利用这两个高度创新的研究项目中令人兴奋的活动和可用资源， 中心的结构和方法旨在扩大多元化基因组科学家、临床医生的人才库 能够进行尖端研究的科学家、博士级和技术人员级别的研究人员 多学科基因组学研究。该中心的劳动力发展核心包括努力发展 对遗传学和基因组学职业感兴趣的西班牙裔预科学生的管道，以便劳动力 发展计划将在未来扩大并实现自我维持。该中心的社区 参与核心旨在提高以西班牙裔为主的当地人口的基因组素养， 增加参与基因组研究的兴趣。这两个多学科项目的研究 该中心支持的重点是对墨西哥当地居民造成重大健康差异的疾病 美国人口、非酒精性脂肪肝和重度抑郁症。团队以科学为中心 研究对我们的学员来说很有意义，因为所调查的疾病会产生不成比例的影响 墨西哥裔美国家庭。研究项目利用最先进的仪器来提供 为教师、学生、博士后和住院医师提供出色的培训机会。尖端技术是 纳入项目，最大限度地发挥培训和研究经验的影响。技术和 项目中使用的方法包括生物信息学、计算基因组学、统计遗传学、分子生物学 遗传学、遗传流行病学、基因组学、蛋白质组学、暴露组学、干细胞生物学、新的统计方法、 环境化学、环境流行病学、神经科学、成像基因组学和医学 人类学。拟议的研究领域提供了一系列出色的培训机会并且内容丰富 为寻求基因组学分支的初级教师和高级教师提供潜在的衍生项目。通过 其行政核心、劳动力发展核心、社区参与核心和研究的活动 项目，拟议的 UTRGV 基因组研究多样性中心将支持尖端基因组研究 在美国最大的西班牙裔服务机构之一进行基因组学研究、能力建设和培训。