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Trial to Evaluate the Immunogenicity of Dose Reduction Strategies of the MVA-BN Mpox Vaccine

Trial to Evaluate the Immunogenicity of Dose Reduction Strategies of the MVA-BN Mpox Vaccine
MVA-BN Mpox 疫苗剂量减少策略免疫原性评估试验
批准号：
10901812
负责人：
BARRY GAUSE
金额：
$42.97万
依托单位：
LEIDOS BIOMEDICAL RESEARCH, INC.
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
项目状态：
已结题
起止时间：
2020-08-31 至 2024-08-30
来源：
https://reporter.nih.gov/project-details/10901812
关键词：
2019-nCoVBiological AssayCOVID-19 impactCOVID-19 therapeuticsCirculationClinical ResearchContractsDiagnosticDoseEpidemiologyEvolutionFundingFutureGenomeHypersensitivityImmune EvasionImmune responseIn VitroInfectionLocationMonkeypoxMonoclonal AntibodiesNational Institute of Allergy and Infectious DiseaseObservational StudyPublic HealthResearch PersonnelSARS-CoV-2 genomeSARS-CoV-2 variantSamplingSeverity of illnessSpecimenTestingTherapeuticVaccinesVariantViralViruscoronavirus diseasegenetic variantgenome sequencingimmunogenicitytargeted treatmentvaccine efficacywhole genome

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中文摘要
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英文摘要
This study is a Phase 2 randomized, open-label, non-placebo controlled, multi-site clinical trial that will evaluate two intradermal (ID) regimens for Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine compared to the standard subcutaneous (SC) regimen in healthy, vaccinia-naïve adults 18 to 50 years of age.
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NIAID- VRC- Evaluating mRNA Vaccine Candidates and Capability Development
  • 批准号：
    10722429
  • 项目类别：
  • 资助金额：
    $152.73万
  • 财政年份：
    2020
  • 负责人：
    BARRY GAUSE
  • 依托单位：
    LEIDOS BIOMEDICAL RESEARCH, INC.
NIAID DCR OPERATIONAL TASK ORDERCOVID FUNDING SUPPORTS THE NIAID DCR COVID WEBSITE AND THE VARIANT TESTING SAVE PROGRAM FOR VARIANT TESTING.
NIAID DCR OPERATIONAL TASK ORDERCOVID FUNDING SUPPORTS THE NIAID DCR COVID WEBSITE AND THE VARIANT TESTING SAVE PROGRAM FOR VARIANT TESTING.
  • 批准号：
    10708257
  • 项目类别：
  • 资助金额：
    $120.0万
  • 财政年份：
    2020
  • 负责人：
    BARRY GAUSE
  • 依托单位：
    LEIDOS BIOMEDICAL RESEARCH, INC.
NIAID DCR OPERATIONAL TASK ORDER FOR DMID COVAIL SUPPORT
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