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Expansion and Characterization of Relevant Simian Immunodeficiency Virus (SIV) Stocks for Use in Drug Assays or Repeat, Low-Dose Challenge Studies in Rhesus Macaques

Expansion and Characterization of Relevant Simian Immunodeficiency Virus (SIV) Stocks for Use in Drug Assays or Repeat, Low-Dose Challenge Studies in Rhesus Macaques
用于恒河猴药物测定或重复、低剂量攻击研究的相关猿猴免疫缺陷病毒 (SIV) 库存的扩展和表征
批准号：
10903691
负责人：
PETER SILVERA
金额：
$0.15万
依托单位：
ADVANCED BIOSCIENCE LABORATORIES, INC.
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
项目状态：
已结题
起止时间：
2018-07-16 至 2022-01-31
来源：
https://reporter.nih.gov/project-details/10903691
关键词：
Animal ModelBiological AssayCollaborationsContractorContractsDoseHIVIn VitroInvestigator-Initiated ResearchMacaca mulattaNational Institute of Allergy and Infectious DiseaseNucleosidesPharmaceutical PreparationsPreventionRNA-Directed DNA PolymeraseResourcesSIVServicesTitrationsVaginaVirusVirus Diseasesin vivoinhibitormanufacturemicrobicidepre-clinicalproduct developmentresearch study

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中文摘要
翻译
杀菌剂和生物医学预防综合资源合同的目的是为NIAID提供一整套临床前产品开发服务，用于研究人员发起的研究或与外部公司或组织合作产生的候选产品。承包商应提供：1)临床前填补服务；2)支持产品开发的HIV动物模型；3)生物分析支持服务；4)产品制造；5)科学和质量/监管支持服务。
英文摘要
The purpose of the Comprehensive Resources for Microbicides and Biomedical Prevention contract is to provide the NIAID with a comprehensive suite of preclinical product development services for candidate products that emerge from investigator-initiated research studies or from collaborations with outside companies or organizations. The Contractor shall provide: 1) Preclinical gap-filling services; 2) HIV animal models supporting product development; 3) Bioanalytical support services; 4) Product manufacturing; and 5) Scientific and quality/regulatory support services.
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会议论文
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