妊娠期糖尿病、围产期抑郁症和后代神经发育表型-猫眼课题宝

妊娠期糖尿病、围产期抑郁症和后代神经发育表型

批准号：

10915172

负责人：

Lauren Christine Shuffrey

金额：

$24.9万

依托单位：

NEW YORK UNIVERSITY SCHOOL OF MEDICINE

依托单位国家：

美国

项目类别：

财政年份：

2023

资助国家：

美国

项目状态：

未结题

起止时间：

2023-08-01 至 2026-07-31

来源：

https://reporter.nih.gov/project-details/10915172

关键词：

Affect Age Months Anxiety Attention Attentional deficit Auditory Award Behavioral Biological Biological Assay Biomedical Research Biometry Birth Blood Brain Buffers Child Child Mental Health Clinical Research Data Data Set Development Diagnosis Disease Electroencephalography Emotional Event-Related Potentials Exposure to Funding Future Gestational Diabetes Goals Health Infant Inflammation Inflammatory Interferon Type II Interleukin-1 beta Interleukin-6 Intervention K-Series Research Career Programs Knowledge Kynurenine Maternal Health Measures Medical Records Memory Mental Depression Mental Health Metabolic Methodology Neurodevelopmental Disorder Newborn Infant Outcome Pathway interactions Perinatal Phase Phenotype Plasma Postpartum Depression Postpartum Period Pregnancy Proteins Research Risk Risk Factors Role Serum Shapes Stress TNF gene Toddler Training Tryptophan Underrepresented Populations United States Venipunctures Visual Woman antepartum depression cohort comorbidity density disparities in morbidity ethnic minority population experience health disparity immune function indexing maternal depression maternal risk modifiable risk neonatal brain neural neurobehavioral offspring perinatal mental health perinatal women peripartum depression postnatal prenatal prenatal exposure prospective psychosocial racial minority population skills social sustained attention translational research program

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英文摘要

PROJECT SUMMARY This K99 application aims to determine pathways by which gestational diabetes mellitus (GDM) and prenatal depression affect postpartum maternal mental health, neonatal brain function, and toddler brain-behavioral development. There is a bidirectional association between GDM and depression which affect approximately 10% and 13% of women in the United States respectively and disproportionately affect women from ethnic and racial minority groups. Both conditions are independently associated with adverse neurodevelopmental outcomes in offspring including increased risk for social-emotional and attentional deficits. Despite the

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Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental Phenotype

批准号：

10301733
项目类别：
资助金额：

$13.08万
财政年份：

2021
负责人：

Lauren Christine Shuffrey
依托单位：

COLUMBIA UNIVERSITY HEALTH SCIENCES

Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental Phenotype

批准号：

10463820
项目类别：
资助金额：

$13.08万
财政年份：

2021
负责人：

Lauren Christine Shuffrey
依托单位：

COLUMBIA UNIVERSITY HEALTH SCIENCES

Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental Phenotype

项目摘要

项目成果

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