Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental Phenotype
Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental Phenotype
妊娠期糖尿病、围产期抑郁症和后代神经发育表型
批准号：
10463820
负责人：
Lauren Christine Shuffrey
金额：
$13.08万
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
项目状态：
已结题
起止时间：
2021-08-06 至 2023-07-31
关键词：
AffectAge-MonthsAnxietyAttentionAttentional deficitAuditoryAwardBehavioralBiologicalBiological AssayBiometryBirthBloodBrainBuffersChildChild Mental HealthClinical ResearchDataData SetDevelopmentDiagnosisDiseaseElectroencephalographyEmotionalEvent-Related PotentialsExposure toFundingFutureGestational DiabetesGoalsHealthInfantInflammationInflammatoryInterferon Type IIInterleukin-1 betaInterleukin-6InterventionK-Series Research Career ProgramsKnowledgeKynurenineMaternal HealthMeasuresMedical RecordsMemoryMental DepressionMental HealthMetabolicMethodologyNeurodevelopmental DisorderNewborn InfantOutcomePathway interactionsPerinatalPhasePhenotypePlasmaPostpartum DepressionPostpartum PeriodPregnancyProteinsResearchRiskRisk FactorsRoleSerumShapesStressSumTNF geneTimeToddlerTrainingTryptophanUnderrepresented PopulationsUnited StatesVenipuncturesVisualWomanantepartum depressioncohortcomorbiditydensitydisparities in morbidityethnic minorityexperiencehealth disparityimmune functionindexingmaternal depressionmaternal riskmodifiable riskneonatal brainneurobehavioraloffspringperinatal mental healthperinatal womenperipartum depressionpostnatalprenatalprenatal exposureprospectivepsychosocialracial minority populationrelating to nervous systemskillssocialsustained attentiontranslational research program
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PROJECT SUMMARY
This K99 application aims to determine pathways by which gestational diabetes mellitus (GDM) and prenatal
depression affect postpartum maternal mental health, neonatal brain function, and toddler brain-behavioral
development. There is a bidirectional association between GDM and depression which affect approximately
10% and 13% of women in the United States respectively and disproportionately affect women from ethnic and
racial minority groups. Both conditions are independently associated with adverse neurodevelopmental
outcomes in offspring including increased risk for social-emotional and attentional deficits. Despite the
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The Association of Nutrition and Exercise Behaviors of Women with Diabetes in Pregnancy with Infant Breastfeeding Practices.
妊娠期糖尿病妇女的营养和运动行为与婴儿母乳喂养的关系。
妊娠期糖尿病妇女的营养和运动行为与婴儿母乳喂养的关系。
DOI：
10.1089/bfm.2023.0059
发表时间：
2023
期刊：
Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine
影响因子：
--
作者：
[Fernández,CristinaR, Guan,Lucy, Rodriguez,Cynthia, Zork,Noelia, Barbosa,Jennifer, Shuffrey,LaurenC]
通讯作者：
Shuffrey,LaurenC
Association of Gestational Diabetes Mellitus and Perinatal Maternal Depression with Early Childhood Behavioral Problems: An Environmental Influences on Child Health Outcomes (ECHO) Study.
妊娠糖尿病和围产期母亲抑郁与幼儿行为问题的关联：环境对儿童健康结果的影响 (ECHO) 研究。
妊娠糖尿病和围产期母亲抑郁与幼儿行为问题的关联：环境对儿童健康结果的影响 (ECHO) 研究。
DOI：
10.1111/cdev.13938
发表时间：
2023
期刊：
Child development
影响因子：
4.6
作者：
[Shuffrey,LaurenC, Morales,Santiago, Jacobson,MelanieH, BosquetEnlow,Michelle, Ghassabian,Akhgar, Margolis,AmyE, Lucchini,Maristella, Carroll,KeciaN, Crum,RosaM, Dabelea,Dana, Deutsch,Arielle, Fifer,WilliamP, Goldson,Brandon, Hockett,C]
通讯作者：
Hockett,C
DOI：
10.1002/dev.22271
发表时间：
2022-05
期刊：
Developmental psychobiology
影响因子：
2.2
作者：
[]
通讯作者：
DOI：
10.1136/bmjopen-2021-058135
发表时间：
2022-04-13
期刊：
BMJ open
影响因子：
2.9
作者：
[Shuffrey LC, Sania A, Brito NH, Potter M, Springer P, Lucchini M, Rayport YK, Du Plessis C, Odendaal HJ, Fifer WP]
通讯作者：
Fifer WP
DOI：
10.1371/journal.pone.0264733
发表时间：
2022
期刊：
PloS one
影响因子：
3.7
作者：
[Firestein MR, Kliman HJ, Sania A, Brink LT, Holzer PH, Hofmann KM, Milano KM, Pini N, Shuffrey LC, Odendaal HJ, Fifer WP]
通讯作者：
Fifer WP
Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental Phenotype
-
批准号：10915172
-
项目类别：
-
资助金额：$24.9万
-
财政年份：2023
-
负责人：Lauren Christine Shuffrey
-
依托单位：
Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental Phenotype
-
批准号：10301733
-
项目类别：
-
资助金额：$13.08万
-
财政年份：2021
-
负责人：Lauren Christine Shuffrey
-
依托单位：