Dynamic Personalized Feedback for Young Adults with a History of Alcohol-Induced Blackout

为有酗酒史的年轻人提供动态个性化反馈

• 批准号: 10620609
• 负责人: Mary Elizabeth Miller
• 金额: $ 21.9万
• 依托单位: UNIVERSITY OF MISSOURI-COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-15 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10620609
• 关键词: Age; Alcohol abuse; Alcohol consumption; Alcoholic beverage heavy drinker; Alcohols; Awareness; Behavior; Blood alcohol level measurement; Communities; Costs and Benefits; Data; Economic Burden; Emergency department visit; Evaluation; Event; Feedback; Female; Frequencies; Goals; Health; Health behavior; Heavy Drinking; Incidence; Individual; Injury; Intervention; Language; Link; Mediator; Medical Care Costs; Memory Loss; Moods; Motivation; National Institute on Alcohol Abuse and Alcoholism; Outcome; Participant; Pattern; Perception; Pharmaceutical Preparations; Phase; Randomized; Randomized, Controlled Trials; Reaction; Recording of previous events; Reporting; Research; Sampling; Self Efficacy; Severities; Sleep; Speed; Strategic Planning; Testing; Treatment Efficacy; Variant; Woman; acceptability and feasibility; alcohol consequences; alcohol intervention; alcohol related consequences; alcohol related problem; alcohol use disorder; brief alcohol intervention; brief intervention; clinical practice; cost; depressive symptoms; design; deter alcohol use; drinking; drinking behavior; efficacy evaluation; efficacy testing; experience; feasibility testing; follow-up; group intervention; heavy drinking young adult; high intensity drinking; high risk; high risk drinking; innovation; interest; intervention cost; intervention participants; intervention refinement; men; mortality; novel; pilot test; post intervention; preventive intervention; primary outcome; prospective; prototype; public health relevance; randomized trial; recruit; response; revictimization; secondary outcome; sexual coercion; social; young adult

PROJECT SUMMARY / ABSTRACT Approximately 50% of young adults who drink alcohol experience alcohol-induced “blackouts,” defined as permanent (en bloc) or temporary (fragmentary) memory loss for events that occurred while they are drinking. This experience of alcohol-induced blackout is associated prospectively with alcohol-related harm, including emergency room visits and sexual coercion, with medical care costs exceeding $469,000 per year. While young adults who have recently experienced a blackout report less favorable evaluations of drinking events and increased motivation to decrease their drinking, they do not actually change their drinking behavior as a result of the blackout alone. Collectively, these data suggest that blackouts may serve as an opportunity for intervention, after which young adults are more likely to respond to alcohol feedback. This R34 aims to develop an intervention tailored to individuals who experience blackouts. The research team developed a dynamic personalized feedback intervention for young adults with a history of blackout. In the first phase of this research (Aim 1 user testing), 15-20 young adults with a history of blackout will provide their perspectives on the proposed content, layout, and language of the intervention. In the second phase of the project (Aim 1 pilot testing), 15 young adults with a history of blackout will pilot the intervention and then provide feedback on their experience with and reactions to delivery. In the final phase (Aim 2 preliminary efficacy testing), 162 young adults (50% female, ≥50% non-college) who report a history of blackout will be randomly assigned to receive the intervention (n=81) or assessment only (n=81). Outcomes will be assessed immediately post-intervention and at 3-month follow-up. Primary outcomes include feasibility (recruitment/retention) and acceptability of the intervention, frequency of high-intensity drinking, peak blood alcohol concentration (BAC), frequency of blackouts, and alcohol-related consequences. Secondary outcomes include incidence of sexual coercion or emergency room visits, perceived likelihood and aversiveness of blackouts, cost/benefits of alcohol use, and self-efficacy of avoid blackouts. Results will inform an R01 randomized trial examining the efficacy and mediators/moderators of the intervention in a larger sample of heavy-drinking young adults. This study will provide initial evidence that blackouts are a feasible and motivating target for brief alcohol interventions.

项目总结/摘要 大约50%的饮酒的年轻人会经历酒精引起的"停电"，定义为： 永久性（整体）或暂时性（片段）记忆丧失的事件，而他们正在喝酒。 这种酒精引起的昏厥的经历与酒精相关的伤害有关，包括 急诊室就诊和性胁迫，每年的医疗费用超过469 000美元。而 最近经历过一次短暂性失忆的年轻人对饮酒事件的评价不太好 和增加的动机，以减少他们的饮酒，他们实际上并没有改变他们的饮酒行为， 这仅仅是停电的结果。总的来说，这些数据表明，停电可能是一个机会， 干预后，年轻人更有可能对酒精反馈做出反应。R34旨在开发 这是一项针对经历过停电的人的干预措施。研究小组开发了一种动态的 对有过昏厥史的年轻人进行个性化反馈干预。在第一阶段， 研究（目标1用户测试），15 - 20名有停电史的年轻人将提供他们的观点， 建议的干预内容、布局和语言。在项目的第二阶段（目标1试点 测试），15名有停电史的年轻人将试点干预，然后提供他们的反馈。 对分娩的经验和反应。在最后阶段（目标2初步疗效测试），162名年轻人 报告有昏厥史的成年人（50%女性，≥ 50%非大学生）将被随机分配接受 干预（n = 81）或仅评估（n = 81）。干预后将立即评估结局 和3个月随访时。主要结果包括可行性（招聘/保留）和可接受性， 干预，高强度饮酒频率，血液酒精浓度峰值， 昏迷和酒精相关的后果次要结果包括性胁迫的发生率， 急诊室就诊，感知的停电可能性和厌恶程度，酒精使用的成本/收益，以及 避免停电的自我效能。结果将告知R01随机试验， 调解人/调解人的干预在大量饮酒的年轻人的更大样本。本研究将 提供初步证据表明，停电是一个可行的和激励目标，短暂的酒精干预。