课题基金 / 基金详情

Pre-doctoral Training in Fundamental Approaches to Biochemistry and Cell and Molecular Biology

Pre-doctoral Training in Fundamental Approaches to Biochemistry and Cell and Molecular Biology
生物化学、细胞和分子生物学基础方法的博士前培训
批准号:
10620298
负责人:
Mary Gehring
金额:
$159.16万
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
未结题
起止时间:
2021-07-01 至 2026-06-30

项目摘要

项目成果

Mary Gehring的其他基金

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中文摘要
翻译
这项建议是为了支持哈佛大学细胞、生化和分子科学的博士前项目 麻省理工学院。我们的使命是培养下一代 生物/生物医学科学家,其中许多人将成为研究、教育和 其他字段。这项建议建立在与以下公司46年合作伙伴关系发展的出色培训记录的基础上 NIGMS。我们的目标是:教育学生了解基本的和潜在的原则 分子、生化和细胞生物学,培养学生成为批判性和创造性的思考者,准备 学生成为道德决策者,教授并提供书面和口头交流的实践,提供 有教学和指导较年轻学生的经验,指导学生变得有效和严谨 研究人员,指导学生完成和发表研究项目,建议学生 确定最适合他们兴趣和技能的职业,提供包容性的学习和研究 环境,并扩大不同背景的个人对生物医学研究的参与 事业。我们招收和培养来自多数族裔、代表不足的少数族裔、残疾人和 弱势群体。我们项目录取的实习生学习成绩优异,实力雄厚 追求研究的动力和能力。我们计划的一个主要特点是密集、重点突出的课程 这是所有一年级学生的必修课。学生在讲课和讨论式的课程中一起工作,由 致力于掌握支撑分子生物科学的一套基本方法的教师。这个 培训计划使学生接触到生物系所有教职员工的研究兴趣 在与第一学期课程相结合的一系列轮换之前,支持明智的选择 论文导师和选题。学生在科学交流和教学中获得经验 辅导低年级学生。负责任的研究行为在课堂和实验室中都被教授 环境,包括为二年级学生开设的高强度迷你课程。学生们有很多学习的机会 关于博士培训后向他们开放的职业道路。学生在该项目中的进步是 在研究生的监督下,定期与教职员工召开论文委员会会议 委员会审议阶段。我们寻求建立和维持一个欢迎和支持所有学生的社区 受到重视并被包括在内。这笔培训赠款将构成约50%的培训赠款的关键支助来源 在我们项目的头两年,符合条件的研究生。我们的学生进行研究 突出的质量,大多数学员继续在生物医学研究的职业生涯。我们以前的许多实习生 现在是他们所选择的领域的领导者,并将知识、严谨、深思熟虑 我们在麻省理工学院生物学课程中强调的公平和包容的观点和价值观。我们期待着激动人心的 我们校友的未来,因为他们帮助改变了美国的生物医学格局。
英文摘要
This proposal is for support of the pre-doctoral program in Cellular, Biochemical and Molecular Science at the Massachusetts Institute of Technology (MIT). Our mission is to train the next generation of biological/biomedical scientists, many of whom will be innovators and leaders in research, education, and other fields. This proposal builds on an outstanding training record developed over a 46-year partnership with NIGMS. Our aims are to: educate students to understand the fundamental and underlying principles of molecular, biochemical, and cellular biology, train students to be critical and creative thinkers, prepare students to be ethical decision makers, teach and provide practice in written and oral communication, provide experience with teaching and mentoring younger students, mentor students to become effective and rigorous researchers, guide students through completion and publication of research projects, advise students as they determine the best-fit careers for their interests and skills, provide an inclusive learning and research environment, and broaden participation of individuals with diverse backgrounds in biomedical research careers. We recruit and train talented students from majority, underrepresented minority, disabled, and disadvantaged populations. Trainees admitted to our program have outstanding academic records and strong motivation and aptitude to pursue research. A key feature of our program is an intensive, focused curriculum required of all first-year students. Students work together in lecture and discussion-style courses taught by dedicated faculty to master a fundamental set of approaches that underpin molecular biological science. The training program exposes students to the research interests of all faculty members in the Biology Department prior to a sequence of rotations that, in combination with first-semester courses, support an informed choice of a thesis advisor and topic. Students gain experience in scientific communication and in teaching and mentoring junior students. Responsible conduct of research is taught in both classroom and laboratory settings, including an intense mini-course for 2nd year students. Students have many opportunities to learn about career paths open to them following doctoral training. Students’ progress through the program is monitored in regular thesis committee meetings with faculty members, with oversight by the graduate committee. We seek to build and maintain a welcoming and supportive community in which all students are valued and included. This training grant would constitute a critical source of support for ~50% of training-grant eligible graduate students in our program during their first two years. Our students perform research of outstanding quality, and most trainees go on to careers in biomedical research. Many of our former trainees are now leaders in their chosen fields and bring to their positions the knowledge, rigor, thoughtful perspectives, and values of equity and inclusion that we emphasize at MIT Biology. We anticipate exciting futures for our alumni as they help transform the US biomedical landscape.
期刊论文(3)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1101/gr.278073.123
发表时间: 2023-09
期刊: GENOME RESEARCH
影响因子: 7
作者: [Shi, Charlie Y., Elcavage, Lara E., Chivukula, Raghu R., Stefano, Joanna, Kleaveland, Benjamin, Bartel, David P.]
通讯作者: Bartel, David P.
Cell-selective proteomics reveal novel effectors secreted by an obligate intracellular bacterial pathogen.
细胞选择性蛋白质组学揭示了专性细胞内细菌病原体分泌的新型效应子。
DOI: 10.1101/2023.11.17.567466
发表时间: 2023
期刊: bioRxiv : the preprint server for biology
影响因子: --
作者: [Sanderlin,AllenG, Margolis,HannahK, Meyer,AbigailF, Lamason,RebeccaL]
通讯作者: Lamason,RebeccaL
The Ankyrin Repeat Protein RARP-1 Is a Periplasmic Factor That Supports Rickettsia parkeri Growth and Host Cell Invasion.
锚蛋白重复蛋白 RARP-1 是一种支持帕克立克次体生长和宿主细胞侵袭的周质因子。
DOI: 10.1128/jb.00182-22
发表时间: 2022
期刊: Journal of bacteriology
影响因子: 3.2
作者: [Sanderlin,AllenG, Hanna,RuthE, Lamason,RebeccaL]
通讯作者: Lamason,RebeccaL
2023 Epigenetics Gordon Research Conference and Gordon Research Seminar
  • 批准号:
    10755875
  • 项目类别:
  • 资助金额:
    $0.5万
  • 财政年份:
    2023
  • 负责人:
    Mary Gehring
  • 依托单位:
Function and Mechanisms of Epigenetic Stability and Dynamics in Arabidopsis
Function and Mechanisms of Epigenetic Stability and Dynamics in Arabidopsis
Regulation of DNA methylation homeostasis in Arabidopsis
海外基金