Driving Biomedical Projects - Functional genomics resources for the Drosophila
Driving Biomedical Projects - Functional genomics resources for the Drosophila
批准号:
10620332
负责人:
NORBERT PERRIMON
金额:
$22.62万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
未结题
起止时间:
2019-08-01 至 2025-04-30
关键词:
AddressAdvisory CommitteesAedesAreaAutomobile DrivingBedsBiologicalBiomedical TechnologyCRISPR/Cas technologyCancer BiologyCell LineCellsCellular AssayCellular biologyCellularityClustered Regularly Interspaced Short Palindromic RepeatsCollaborationsCommunicable DiseasesCommunicationCommunitiesComplexCulicidaeDNA Repair PathwayDataData SetDevelopmentDevelopmental BiologyDiseaseDisease VectorsDistantDrosophila genusEndoplasmic ReticulumEnsureEquilibriumGenesGenetic Complementation TestGenetic TranscriptionGenomic approachGeographic DistributionGoalsGrantHealthIn VitroIndividualInstitutionKnock-outLabelLearningLibrariesLipidsMalignant NeoplasmsMonitorMosquito-borne infectious diseaseNeurobiologyPositioning AttributeProcessProtein EngineeringProteinsProteomicsProtocols documentationRNA InterferenceResearchResearch PersonnelResearch Project GrantsResourcesSignal TransductionSystems DevelopmentTechnologyTestingTherapeuticTranscriptional RegulationUS StateVector-transmitted infectious diseaseVisualizationWorkcancer typecommon ruledesignexperiencefunctional genomicsgenetic approachgenetic resourcegenome editinggenome resourcegenome-widehuman diseaseimprovedin vivoinsightinterestnanobodiespathogenpathogenic virusprotein distributionprotein functionrare genetic disorderscreeningsuccesstechnology developmenttherapy developmentvector mosquito
中文摘要
项目总结——驱动生物医学项目
英文摘要
PROJECT SUMMARY – DRIVING BIOMEDICAL PROJECTS
We have identified a diverse set of driving biomedical projects (DBPs) that will serve as test-beds for
development of technologies by the Drosophila Research Screening Center-Biomedical Technology Research
Resource (DRSC-BTRR). The topic areas include cancer therapeutics, rare genetic disease, mosquito-borne
infectious diseases, and fundamental studies, for example in the areas of cell and developmental biology. We
will work with these researchers to ensure that technologies are tested by collaborators, further developed and
refined by the DRSC-BTRR, and applied to fit their research needs. We will also ensure that data generated by
and for one project are used to improve all relevant projects, for example as will be relevant in the area of
CRISPR pooled screens in Drosophila and mosquito cells, and in development of nanobodies for mosquito and
Drosophila targets. Altogether, our DBPs are well-positioned to test and benefit from the technologies, resulting
in studies with strong potential to provide new insights into a variety of fundamental and translational topics.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Drosophila models of human mitochondrial diseases
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批准号:10756280
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项目类别:
-
资助金额:$86.73万
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财政年份:2023
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负责人:NORBERT PERRIMON
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依托单位:
Resources for functional studies in Drosophila
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批准号:10597005
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项目类别:
-
资助金额:$55.56万
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财政年份:2022
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负责人:NORBERT PERRIMON
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依托单位:
CANCAN - Harvard
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批准号:10845771
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项目类别:
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资助金额:$20.14万
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财政年份:2022
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负责人:NORBERT PERRIMON
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依托单位:
Resources for functional studies in Drosophila
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批准号:10332199
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项目类别:
-
资助金额:$54.5万
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财政年份:2022
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负责人:NORBERT PERRIMON
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依托单位:
CANCAN - Harvard
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批准号:10625727
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项目类别:
-
资助金额:$20.4万
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财政年份:2022
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负责人:NORBERT PERRIMON
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依托单位:
TRiP resources for modeling human disease
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批准号:10456523
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项目类别:
-
资助金额:$31.59万
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财政年份:2020
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负责人:NORBERT PERRIMON
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依托单位:
TRiP resources for modeling human disease
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批准号:10206288
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项目类别:
-
资助金额:$63.37万
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财政年份:2020
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负责人:NORBERT PERRIMON
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依托单位:
TRiP resources for modeling human disease
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批准号:10374128
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项目类别:
-
资助金额:$63.56万
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财政年份:2020
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负责人:NORBERT PERRIMON
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依托单位:
TRiP resources for modeling human disease
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批准号:10047112
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项目类别:
-
资助金额:$63.37万
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财政年份:2020
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负责人:NORBERT PERRIMON
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依托单位:
TRiP resources for modeling human disease
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批准号:10598494
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项目类别:
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资助金额:$63.56万
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财政年份:2020
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负责人:NORBERT PERRIMON
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依托单位:
Functional genomics resources for the Drosophila and broader research communities
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批准号:10436790
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项目类别:
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资助金额:$135.6万
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财政年份:2019
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负责人:NORBERT PERRIMON
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依托单位:
Functional genomics resources for the Drosophila and broader research communities
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批准号:10620324
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项目类别:
-
资助金额:$135.6万
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财政年份:2019
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负责人:NORBERT PERRIMON
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依托单位:
Driving Biomedical Projects - Functional genomics resources for the Drosophila
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批准号:10436796
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项目类别:
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资助金额:$22.62万
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财政年份:2019
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负责人:NORBERT PERRIMON
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依托单位:
Admin Core - Functional genomics resources for the Drosophila
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批准号:10436791
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项目类别:
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资助金额:$9.84万
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财政年份:2019
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负责人:NORBERT PERRIMON
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依托单位:
Admin Core - Functional genomics resources for the Drosophila
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批准号:10620325
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项目类别:
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资助金额:$9.84万
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财政年份:2019
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负责人:NORBERT PERRIMON
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依托单位:
Identification of Presinilin downstream targets in neuronal survival
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批准号:9325265
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项目类别:
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资助金额:$67.82万
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财政年份:2017
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负责人:NORBERT PERRIMON
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依托单位:
Next-generation Drosophila cell lines to elucidate the cellular basis of human diseases
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批准号:9358767
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项目类别:
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资助金额:$67.13万
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财政年份:2017
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负责人:NORBERT PERRIMON
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依托单位:
Identification of Presinilin downstream targets in neuronal survival
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批准号:9896883
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项目类别:
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资助金额:$73.41万
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财政年份:2017
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负责人:NORBERT PERRIMON
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依托单位:
Identification of Presinilin downstream targets in neuronal survival
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批准号:9444406
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项目类别:
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资助金额:$73.41万
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财政年份:2017
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负责人:NORBERT PERRIMON
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依托单位:
Next-generation Drosophila cell lines to elucidate the cellular basis of human diseases
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批准号:9763671
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项目类别:
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资助金额:$65.53万
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财政年份:2017
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负责人:NORBERT PERRIMON
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依托单位:
海外基金