CTSA UM1 Program at University of Utah

犹他大学 CTSA UM1 项目

• 批准号: 10622226
• 负责人: RACHEL HESS
• 金额: $ 546.17万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2030-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10622226
• 关键词: Acceleration; Address; Award; Biomedical Research; Caring; Clinic; Clinical; Clinical Data; Clinical Research; Clinical Sciences; Clinical and Translational Science Awards; Collaborations; Communities; Country; Data; Development; Dissemination and Implementation; Ecosystem; Education; Effectiveness; Elderly; Ensure; Equity; Ethics; Ethnic Population; Evaluation; Extramural Activities; Fostering; Foundations; Funding; Genetic; HIV; Health; Health Services; Hearing; Hematologist; Hereditary Disease; Individual; Informatics; Infrastructure; Institution; Internal Medicine; International; Investments; Knowledge; Leadership; Lesbian Gay Bisexual Transgender Queer; Life Cycle Stages; Measurable; Metabolic Diseases; Methods; Mission; Modeling; Modernization; Muscular Dystrophies; National Center for Advancing Translational Sciences; Participant; Patients; Population; Program Development; Provider; Race; Recording of previous events; Reduce health disparities; Reproducibility; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Rural; Science; Scientist; Series; Services; Social Justice; Strategic Planning; Sum; Techniques; Testing; Training; Translating; Translational Research; United States National Institutes of Health; Universities; Utah; Vision; Voice; Workforce Development; bench to bedside; community engagement; design; effectiveness research; experience; frontier; health disparity; health equity; improved; innovation; medical schools; member; next generation; novel; pre-exposure prophylaxis; programs; social health determinants; structural biology; tool; translational pipeline

ABSTRACT The vision of the Utah Clinical & Translational Science Institute (CTSI) is to strategically and ethically develop and apply generalizable and reproducible clinical and translational science (CTS) innovations to increase science equity and health equity, and promote social justice. The Utah CTSI collaborates with local, regional, and national partners and collaborators to achieve this vision through four specific aims: (1) Serve as a well-recognized hub for clinical and translational science that promotes science and health equity in a measurable, reproducible, and sustainable manner. (2) Design, develop, and test innovative translational science methods, tools, techniques, and best practices to increase efficiency and reproducibility. (3) Support the implementation and dissemination of translational science innovations and the education and development of the translational science and research workforce. (4) Catalyze the advancement of translational research discoveries from bench to bedside to populations to improve the health of individuals and communities, reducing health disparities and improving health equity. Through comprehensive and integrated workforce development programs, we will train the next generation of diverse clinicians, bench scientists, informaticians, and health service scientists in the translational, ethical, and team science aspects of modern biomedical research. We will create a novel model and ecosystem for engaging stakeholders who experience health disparities, including underserved racial/ethnic populations, senior citizens, members of LGBTQ+ communities, and rural/frontier residents across the Intermountain West, in order to: ensure that many voices are heard throughout the research life cycle; (potential) research participants are informed, engaged, and supported so that participation is accessible to all; and findings are translated into care that supports health equity. Through our resources and services, we will provide stakeholder engagement, study design and analysis, informatics, ethics, and clinical research infrastructure to the Utah CTSI community (including patients, community members, investigators, and providers). Our Translational Innovation Pilot program will launch novel projects to address generalizable translational science questions, overcoming barriers to accelerate translational research. We will leverage modern informatics techniques to integrate clinical data with social determinants of health and environmental data in an easily accessible format to facilitate quantitative studies seeking to understand how these factors contribute to health disparities. Our CTS Research Program will conduct a series of projects to improve inclusiveness across the translational research lifecycle. Our Strategic Management Team brings together experienced leaders from across the institution, partners, and collaborators to unify our efforts, and ensure efficient administration and implementation of the Utah CTSI's aims. Our Hub Liaison Team will ensure that we have active, diverse partner participation in national NCATS and CTSA efforts, and promote dissemination of CTS innovations across hubs.

抽象的 犹他州临床与转化科学研究所（CTSI）的愿景是在战略和道德上 开发和应用可推广和可重现的临床和转化科学（CTS）创新 增加科学公平和健康公平，并促进社会正义。犹他州CTSI与本地合作 区域和国家合作伙伴和合作者通过四个具体目标来实现这一愿景：（1）作为 公认的临床和转化科学枢纽，可在 可衡量，可重现和可持续的方式。 （2）设计，开发和测试创新的翻译 科学方法，工具，技术和最佳实践，以提高效率和可重复性。 （3）支持 转化科学创新的实施和传播以及教育与发展 转化科学与研究人员。 （4）催化转化研究的进步 从长凳到床头到人口的发现，以改善个人和社区的健康， 减少健康差异并改善健康公平。通过全面而综合的劳动力 开发计划，我们将培训下一代不同的临床医生，替补科学家，知情者， 以及现代生物医学的转化，道德和团队科学方面的卫生服务科学家 研究。我们将创建一个新颖的模型和生态系统，以吸引经历健康的利益相关者 差异，包括服务不足的种族/族裔人口，老年人，LGBTQ+成员 为了：确保许多声音 在整个研究生命周期中都会听到； （潜在的）研究参与者被告知，参与 受支持，以便所有人都可以参与；调查结果被转化为支持健康的护理 公平。通过我们的资源和服务，我们将提供利益相关者参与，学习设计和 向犹他州CTSI社区的分析，信息学，道德和临床研究基础设施（包括 患者，社区成员，调查人员和提供者）。我们的翻译创新试点计划 将启动新颖的项目来解决可概括的翻译科学问题，克服障碍 加速翻译研究。我们将利用现代信息学技术来整合临床数据 具有易于访问格式的健康和环境数据的社会决定因素，以促进 旨在了解这些因素如何促进健康差异的定量研究。我们的CTS 研究计划将进行一系列项目，以改善翻译研究的包容性 生命周期。我们的战略管理团队将来自整个机构的经验丰富的领导人聚集在一起， 合作伙伴和合作者统一我们的努力，并确保有效地管理和实施 犹他州CTSI的目标。我们的枢纽联络小组将确保我们积极，多样化的合作伙伴参与 国家NCAT和CTSA的努力，并促进跨枢纽的CTS创新传播。