CTSA UM1 Program at University of Utah

犹他大学 CTSA UM1 项目

• 批准号: 10622226
• 负责人: RACHEL HESS
• 金额: $ 546.17万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2030-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10622226
• 关键词: Acceleration; Address; Award; Biomedical Research; Caring; Clinic; Clinical; Clinical Data; Clinical Research; Clinical Sciences; Clinical and Translational Science Awards; Collaborations; Communities; Country; Data; Development; Dissemination and Implementation; Ecosystem; Education; Effectiveness; Elderly; Ensure; Equity; Ethics; Ethnic Population; Evaluation; Extramural Activities; Fostering; Foundations; Funding; Genetic; HIV; Health; Health Services; Hearing; Hematologist; Hereditary Disease; Individual; Informatics; Infrastructure; Institution; Internal Medicine; International; Investments; Knowledge; Leadership; Lesbian Gay Bisexual Transgender Queer; Life Cycle Stages; Measurable; Metabolic Diseases; Methods; Mission; Modeling; Modernization; Muscular Dystrophies; National Center for Advancing Translational Sciences; Participant; Patients; Population; Program Development; Provider; Race; Recording of previous events; Reduce health disparities; Reproducibility; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Rural; Science; Scientist; Series; Services; Social Justice; Strategic Planning; Sum; Techniques; Testing; Training; Translating; Translational Research; United States National Institutes of Health; Universities; Utah; Vision; Voice; Workforce Development; bench to bedside; community engagement; design; effectiveness research; experience; frontier; health disparity; health equity; improved; innovation; medical schools; member; next generation; novel; pre-exposure prophylaxis; programs; social health determinants; structural biology; tool; translational pipeline

ABSTRACT The vision of the Utah Clinical & Translational Science Institute (CTSI) is to strategically and ethically develop and apply generalizable and reproducible clinical and translational science (CTS) innovations to increase science equity and health equity, and promote social justice. The Utah CTSI collaborates with local, regional, and national partners and collaborators to achieve this vision through four specific aims: (1) Serve as a well-recognized hub for clinical and translational science that promotes science and health equity in a measurable, reproducible, and sustainable manner. (2) Design, develop, and test innovative translational science methods, tools, techniques, and best practices to increase efficiency and reproducibility. (3) Support the implementation and dissemination of translational science innovations and the education and development of the translational science and research workforce. (4) Catalyze the advancement of translational research discoveries from bench to bedside to populations to improve the health of individuals and communities, reducing health disparities and improving health equity. Through comprehensive and integrated workforce development programs, we will train the next generation of diverse clinicians, bench scientists, informaticians, and health service scientists in the translational, ethical, and team science aspects of modern biomedical research. We will create a novel model and ecosystem for engaging stakeholders who experience health disparities, including underserved racial/ethnic populations, senior citizens, members of LGBTQ+ communities, and rural/frontier residents across the Intermountain West, in order to: ensure that many voices are heard throughout the research life cycle; (potential) research participants are informed, engaged, and supported so that participation is accessible to all; and findings are translated into care that supports health equity. Through our resources and services, we will provide stakeholder engagement, study design and analysis, informatics, ethics, and clinical research infrastructure to the Utah CTSI community (including patients, community members, investigators, and providers). Our Translational Innovation Pilot program will launch novel projects to address generalizable translational science questions, overcoming barriers to accelerate translational research. We will leverage modern informatics techniques to integrate clinical data with social determinants of health and environmental data in an easily accessible format to facilitate quantitative studies seeking to understand how these factors contribute to health disparities. Our CTS Research Program will conduct a series of projects to improve inclusiveness across the translational research lifecycle. Our Strategic Management Team brings together experienced leaders from across the institution, partners, and collaborators to unify our efforts, and ensure efficient administration and implementation of the Utah CTSI's aims. Our Hub Liaison Team will ensure that we have active, diverse partner participation in national NCATS and CTSA efforts, and promote dissemination of CTS innovations across hubs.

摘要 犹他州临床与转化科学研究所（CTSI）的愿景是从战略和道德上 开发和应用可推广和可复制的临床和转化科学（CTS）创新， 促进科学公平和健康公平，促进社会正义。犹他州CTSI与当地， 区域和国家合作伙伴和协作者，通过四个具体目标实现这一愿景： 一个公认的临床和转化科学中心，促进科学和健康的公平， 可测量、可复制和可持续的方式。(2)设计、开发和测试创新的翻译 科学方法、工具、技术和最佳实践，以提高效率和可重复性。(3)支持 翻译科学创新的实施和传播以及 转化科学和研究人员。(4)促进转化研究的发展 从实验室到床边再到人群的发现，以改善个人和社区的健康， 减少健康差距，提高健康公平性。通过全面和综合的工作人员队伍 发展计划，我们将培养下一代不同的临床医生，板凳科学家，信息学家， 现代生物医学的转化，伦理和团队科学方面的健康服务科学家 research.我们将创建一个新的模式和生态系统，让体验健康的利益相关者参与进来。 不平等，包括服务不足的种族/民族人口，老年人，LGBTQ+成员 社区和山区西部的农村/边境居民，以确保许多声音 在整个研究生命周期中听到;（潜在）研究参与者知情，参与， 提供支持，使所有人都能参与;并将研究结果转化为支持健康的护理 股权通过我们的资源和服务，我们将提供利益相关者的参与，研究设计和 分析，信息学，伦理学和临床研究基础设施，以犹他州CTSI社区（包括 患者、社区成员、研究者和提供者）。我们的翻译创新试点计划 将推出新的项目，以解决可推广的转化科学问题，克服障碍， 加快转化研究。我们将利用现代信息技术整合临床数据 以易于获取的格式提供健康和环境数据的社会决定因素， 定量研究试图了解这些因素如何造成健康差距。我们的CTS 研究计划将开展一系列项目，以提高整个转化研究的包容性 生命周期我们的战略管理团队汇集了来自整个机构的经验丰富的领导者， 合作伙伴和合作者，以统一我们的努力，并确保有效的管理和实施， 犹他州CTSI的目标。我们的枢纽联络团队将确保我们有积极的，多样化的合作伙伴参与， 国家计算机技术协会和计算机技术协会的努力，并促进计算机技术协会的创新在各中心的传播。