University of Colorado Rocky Mountain NeuroNEXT (UNCOMON) Clinical Research Consortium.

科罗拉多大学落基山 NeuroNEXT (UNCOMON) 临床研究联盟。

基本信息

  • 批准号:
    10744629
  • 负责人:
  • 金额:
    $ 42.9万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2023
  • 资助国家:
    美国
  • 起止时间:
    2023-07-15 至 2028-06-30
  • 项目状态:
    未结题

项目摘要

Effective clinical research into rare and ultra-rare neurologic and neurogenetic disorders requires a nationwide, collaborative network of neuroscience clinical research centers. The objective of the proposed University of Rocky Mountain NeuroNEXT Clinical Research Consortium (UNCOMON CRC) is to integrate expert from adult and child neurology, neurosurgery, neuroimaging, neuropsychology, and neurogenetics both the University of Colorado Hospital and Children's Hospital of Colorado on the University of Colorado Medical Campus into a large collaborative clinical research enterprise that exceeds start-up, retention, and operational goals of the NeuroNEXT network. The UNCOMON CRC is composed of recognized leaders in clinical research who have successfully participated in federally funded and multi-center clinical trials as well as local investigator-initiated therapeutic and biorepository The UNCOMON CRC will employ established clinical research and educational resources in conjunction a robust clinical research infrastructure to efficiently contribute to the NeuroNEXT network and advance the and research careers of the next generation of junior faculty nd fellows. We plan to achieve our goal the execution of the following specific aims: Aim 1: To establish a leadership network consisting of study adult and pediatric research directors, career enhancement director, DEI recruitment specialist, clinical coordinator, NeuroNEXT fellow, and operations manager; Aim 2: To establish an UNCOMON clinical consortium of collaborative co-investigators from adult and child neurology, neurosurgery, neuropsychology, and neurogenetics that encompass all subspecialty fields of clinical Aim 3: To establish a referral network to optimize recruitment and enhance outreach to minority and rural populations; and Aim 4: To develop and execute clinical research training and enhancement programs f or young i investigators using the collective expertise of the UNCOMON CRC. UNCOMON CRC will work efficiently to accelerate site qualification and IRB approval, employ multiple to optimize subject recruitment and retention, and carefully monitor research operations to ensure data a quality.
对罕见和超罕见神经系统和神经遗传性疾病的有效临床研究需要全国范围内的神经科学临床研究中心合作网络。拟议的落基山大学NeuroNEXT临床研究联盟的目标(UNCOMON CRC)是将科罗拉多大学医院和科罗拉多大学医学院的科罗拉多儿童医院的成人和儿童神经病学、神经外科、神经影像学、神经心理学和神经遗传学专家整合成一个大型的合作临床研究企业,和操作目标的NeuroNEXT网络。UNCOMON CRC由临床研究领域公认的领导者组成,他们成功参与了联邦资助的多中心临床试验以及当地研究者,UNCOMON CRC将利用成熟的临床研究和教育资源,结合强大的临床研究基础设施,有效地为NeuroNEXT网络做出贡献,并推动下一代的研究事业。初级教员和研究员。我们计划通过执行以下具体目标来实现我们的目标:目标1:建立一个由成人和儿科研究负责人、职业发展负责人、DEI招募专家、临床协调员、NeuroNEXT研究员和运营经理组成的领导网络;目标2:建立一个由成人和儿童神经病学、神经外科、神经心理学、目标3:建立一个转诊网络,以优化招募并加强对少数民族和农村人口的推广;目标4:利用UNCOMON CRC的集体专业知识,为年轻的研究人员制定和执行临床研究培训和增强计划。 UNCOMON CRC将高效工作,以加快研究中心资格认证和IRB批准,采用多个优化受试者招募和保留,并仔细监测研究操作,以确保数据质量。

项目成果

期刊论文数量(0)
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专利数量(0)

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TIMOTHY A BENKE其他文献

TIMOTHY A BENKE的其他文献

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{{ truncateString('TIMOTHY A BENKE', 18)}}的其他基金

Multi-Site Validation of Biomarkers and Core Clinical Outcome Measures for Clinical Trials Readiness in CDKL5 Deficiency Disorder
CDKL5 缺乏症临床试验准备的生物标志物和核心临床结果指标的多中心验证
  • 批准号:
    10569019
  • 财政年份:
    2021
  • 资助金额:
    $ 42.9万
  • 项目类别:
Multi-Site Validation of Biomarkers and Core Clinical Outcome Measures for Clinical Trials Readiness in CDKL5 Deficiency Disorder
CDKL5 缺乏症临床试验准备的生物标志物和核心临床结果指标的多中心验证
  • 批准号:
    10338135
  • 财政年份:
    2021
  • 资助金额:
    $ 42.9万
  • 项目类别:
Exploratory determination of the role of L-type calcium channels in mediating abnormal plasticity and behavior after early life seizures
探索性测定 L 型钙通道在介导早期癫痫发作后异常可塑性和行为中的作用
  • 批准号:
    9454781
  • 财政年份:
    2017
  • 资助金额:
    $ 42.9万
  • 项目类别:
Colorado Neurological Sciences Academic Development Award (NSADA)
科罗拉多神经科学学术发展奖 (NSADA)
  • 批准号:
    8788338
  • 财政年份:
    2015
  • 资助金额:
    $ 42.9万
  • 项目类别:
Molecular mechanisms linking early life seizures, autism and intellectual disabil
生命早期癫痫发作、自闭症和智力障碍之间的分子机制
  • 批准号:
    8217756
  • 财政年份:
    2011
  • 资助金额:
    $ 42.9万
  • 项目类别:
Molecular mechanisms linking early life seizures, autism and intellectual disabil
生命早期癫痫发作、自闭症和智力障碍之间的分子机制
  • 批准号:
    8533043
  • 财政年份:
    2011
  • 资助金额:
    $ 42.9万
  • 项目类别:
Molecular mechanisms linking early life seizures, autism and intellectual disabil
生命早期癫痫发作、自闭症和智力障碍之间的分子机制
  • 批准号:
    8323875
  • 财政年份:
    2011
  • 资助金额:
    $ 42.9万
  • 项目类别:
Molecular mechanisms linking early life seizures, autism and intellectual disabil
生命早期癫痫发作、自闭症和智力障碍之间的分子机制
  • 批准号:
    8909216
  • 财政年份:
    2011
  • 资助金额:
    $ 42.9万
  • 项目类别:
Rocky Mountain Network for Neuroscience Clinical Studies (RMNNCS)
落基山神经科学临床研究网络 (RMNNCS)
  • 批准号:
    8866484
  • 财政年份:
    2011
  • 资助金额:
    $ 42.9万
  • 项目类别:
Molecular mechanisms linking early life seizures, autism and intellectual disabil
生命早期癫痫发作、自闭症和智力障碍之间的分子机制
  • 批准号:
    8722047
  • 财政年份:
    2011
  • 资助金额:
    $ 42.9万
  • 项目类别:

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