Rocky Mountain Network for Neuroscience Clinical Studies (RMNNCS)

根据RFA-NS-11-008的要求，我们建议建立落基山神经科学临床研究网络（rmnnc）。该项目将在科罗拉多大学医学院的成人和儿童神经病学部门进行，并将在三个机构之间执行：科罗拉多大学医学院、科罗拉多大学医院和儿童医院。项目主任将由神经病学教授Timothy Vollmer博士和儿童神经病学副教授Paul Levisohn博士共同担任。共同研究者将包括许多在成人和儿童神经学、神经影像学和神经外科方面具有人类研究经验的教员。共同研究者包括脑血管疾病、运动障碍、癫痫、行为/认知神经病学、神经遗传学、神经免疫学、神经眼科学和成人和儿童神经肌肉疾病领域的专家。结合RMNNCS，我们建议建立落基山神经科学临床研究联盟（RMANCS）。这将是rmnnc、社区神经学家和社区患者倡导团体之间的合作，重点关注整个落基山脉地区的神经疾病。这将进一步增强rmnnc为NEXT研究接触罕见患者群体的能力，并为NEXT卓越中心确定新的临床研究概念奠定基础。

DESCRIPTION (provided by applicant): In response to RFA-NS-11-008, we are proposing to develop the Rocky Mountain Network for Neuroscience Clinical Studies (RMNNCS). This program will reside at the University Of Colorado School Of Medicine within the Departments of Adult and Child Neurology, and will be executed between three institutions: University of Colorado School of Medicine, University of Colorado Hospital and The Children's Hospital. The Program Director will be Dr. Timothy Vollmer, M.D., Professor of Neurology, with Co-Program Director Dr. Paul Levisohn M.D., Associate Professor of Child Neurology. Co-Investigators will include numerous faculty members with experience in human research in adult and child neurology neuroimaging, and neurosurgery. Co-investigators include specialists in the fields of Cerebrovascular Disease, Movement Disorders, Epilepsy, Behavioral/Cognitive Neurology, Neurogenetics, Neuroimmunology, Neuroopthalmology and Neuromuscular Disease in both adult and pediatric patients. In conjunction with the RMNNCS, we propose to develop the Rocky Mountain Alliance for Neuroscience Clinical Studies (RMANCS). This will be collaboration between the RMNNCS, community-based neurologists and community-based patient advocacy groups focused on neurological disease from throughout the Rocky Mountain region. This will further enhance RMNNCS' ability to reach rare patient populations for NEXT studies and lay the foundation for identifying new clinical research concepts for the NEXT Centers of Excellence.