Tri-I Stimulating Access to Research in Residency program (Tri-I StARR - NIAID)

摘要： 尽管内科科学家对临床做出了不可替代的贡献，但临床科学家的管道 实习生人数仍在下降。医生-科学家职业生涯的一个关键障碍是缺乏受保护的时间 以及在临床培训期间为医生提供研究指导的机会。随着敏锐度的提高， 现代医学的体量和复杂性，临床培训越来越注重获取和 应用现有的知识，而不是产生新的知识。这一转变的不幸后果是 重点是越来越多地将科学训练划分为不足以 提供精通科学调查所需的培训和连续性。三合一- 机构刺激住院期间研究机会(Tri-I STARR)计划试图纠正这一点 通过开发集成的、纵向的、有指导的研究培训计划来弥补不足，该计划将导致 新的临床干预措施的开发、实施和评估，以预防、诊断、治疗和 改善传染病、免疫学和炎症性病因疾病的健康差异， 来自威尔·康奈尔医学院、洛克菲勒大学和斯隆·凯特林纪念馆的导师。三-我- 斯塔尔将在三个科室对住院医生进行综合临床研究途径的培训：儿科， 医学和病理学在整个生物医学研究连续体的领域，包括主题 生命过程中的医疗保健差距以及健康和疾病。该计划提出了四个培训目标： (1)在科学方法和设计基于假设的项目方面获得技能，以解决人类 生命周期中的疾病及其不平等，(2)设计中的个性化、多学科指导 和完成一个研究项目，(3)发展短期、中期和长期境内流离失所者， 在职业生涯阶段内和跨职业阶段整合科学和临床培训，以及(4)积极参与 在职业阶段和机构内以及跨职业阶段和机构的内科-科学家之间的横向和纵向网络。 Tri-i-STAR将由一个执行委员会(EC)领导，执行委员会由医学博士Kyu Rhee、 Sallie Permar医学博士(儿科学)和Ethel Cesarman医学博士(病理学)，一个扩展的高管 由常驻项目主任和项目协调员组成的委员会(EEC)和一个由36名多人组成的团队 系系、多学科、资金雄厚、经验丰富的教员。三名常驻调查员 每年将支持12个月的研究，并可选择再增加12个月。vt.在.的基础上 完成培训后，学员将能够成功地过渡到研究密集型奖学金培训 竞争后续融资机会，包括K38，这将使他们成为下一个 领导和指导临床研究实习生的一代医生。这项计划将实现 迫切需要：1)全国各地医学院需要更多全职学术医生和研究人员 国家，以及2)创新和临床翻译的新战略，以改善整个寿命的健康。

Abstract: Despite the irreplaceable contributions of physician-scientists to clinical, the pipeline of clinician-scientist trainees remains on the decline. A critical barrier to the physician-scientist career is the lack of protected time and access to research mentorship available to physicians during clinical training. With the heightened acuity, volume and complexities of modern medicine, clinical training has increasingly focused on the acquisition and application of existing, rather than generation of new, knowledge. An unfortunate consequence of this shift in focus is the increasing compartmentalization of scientific training into fragments of time that are inadequate to provide the training and continuity needed to become proficient in the scientific investigation. The Tri- Institutional Stimulating Access to Research during Residency (Tri-I StARR) program seeks to remedy this deficiency by developing an integrated, longitudinal mentored research training program that will lead to the development, implementation, and evaluation of new clinical interventions to prevent, diagnose, treat and ameliorate health disparities of disorders of infectious, immunologic and inflammatory etiologies, with mentorship from across Weill Cornell Medicine, Rockefeller University, and Memorial Sloan Kettering. Tri-I- StARR will train residents on an integrated clinical-research pathway across 3 departments: Pediatrics, Medicine, and Pathology in areas along the full biomedical research continuum and include the themes of healthcare disparities and health and disease over the life course. The program proposes four training aims: (1) Acquisition of skills in the scientific method and design of hypothesis-based projects to address human diseases across the lifespan and their inequities, (2) Individualized, multidisciplinary mentorship in the design and completion of a research project, (3) Development of short, intermediate, and long term IDPs that integrate scientific and clinical training within and across career stages, and (4) Active engagement in horizontal and vertical networking among physician-scientists within and across career stages and institutions. The Tri-I-StARR will be led by an Executive Committee (EC) consisting of Kyu Rhee, MD PhD (Medicine), Sallie Permar, MD, PhD (Pediatrics), and Ethel Cesarman, MD (Pathology), an Expanded Executive Committee (EEC) of Residency Program Directors and Program Coordinators, and a team of 36 multi- departmental, multi-disciplinary, well-funded, and experienced faculty preceptors. Three Resident-Investigators each year will be supported for 12 months of research with the options to add an additional 12 months. Upon completion, trainees will be capable of transitioning to research-intense fellowship training, successfully competing for follow-on funding opportunities, including the K38, that will enable them to become the next generation of physicians leading and mentoring trainees in clinically-oriented research. This program will fulfill the urgent need for: 1) more full-time academic physician-researchers in medical schools throughout the country, and 2) innovations and clinical translation of novel strategies to improve health across the lifespan.