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Health Opportunities & Promoters of Equitable Screening for Lung Cancer (Hopes for Lung Cancer)

健康机会

基本信息

批准号：
10591639
负责人：
Efren Flores
金额：
$ 28.08万
依托单位：
MASSACHUSETTS GENERAL HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-02-03 至 2028-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10591639
关键词：
Address Area Award Awareness COVID-19 Cancer Etiology Charge Clinic Clinical Collaborations Communities Community Health Community Networks Data Dedications Development Plans Disclosure Disparity Documentation Early Diagnosis Education Education and Outreach Educational Intervention Electronic Health Record Electronic Mail Elements Eligibility Determination Environment Equity Focus Groups Foundations Fright Guidelines Health Healthcare Systems Hispanic Hispanic Populations Hospitals Individual Institution Intervention K-Series Research Career Programs Leadership Malignant neoplasm of lung Mental Health Mentors Mentorship Methods Modality Modeling National Institute on Minority Health and Health Disparities Not Hispanic or Latino Outcome Participant Patient Participation Patients Physicians Population Positioning Attribute Provider Publishing Radiology Specialty Research Research Personnel Resources Schedule Scientist Smoker Smoking Status Surveys Text Messaging Theoretical model Training Training Support Underserved Population United States Preventative Services Task Force Vulnerable Populations Work acceptability and feasibility cancer health disparity cancer survival career career development community based participatory research community partnership cost digital delivery digital health digital intervention evidence base experience former smoker health record hispanic community improved innovation interest intervention delivery intervention effect low socioeconomic status lung basal segment lung cancer screening mortality novel outreach patient portal pilot trial prevent promoter research study satisfaction screening guidelines screening participation severe mental illness smoking cessation social culture trial enrollment uptake

项目摘要

PROJECT SUMMARY Candidate: This resubmission for the NCI K08 Mentored Clinical Scientist Research Career Development Award to Promote Diversity describes Efrén J. Flores, MD as a candidate who is well- positioned to successfully complete the proposed training objectives and research aims. Dr. Flores’ background as a Hispanic physician and clinical researcher has focused on achieving equity in lung cancer outcomes through early detection by developing novel interventions to increase LCS uptake among Hispanic and othervulnerable populations. Background: Lung cancer remains the leading cause of cancer-specific mortality in theUS, and Hispanics experience worse lung cancer outcomes and die at higher rates due to advanced stage at presentation. Lung cancer screening (LCS) can save many lives through early lung cancer detection among Hispanic current and former smokers. Still, without increasing efforts to improve smoking status disclosure and documentation and tailored interventions to promote LCS uptake among Hispanic current and former smokers, this underserved population will continue to demonstrate disparities in lung cancer survival. Study aims: Based on prior research experience, Dr. Flores has adapted the NIMHD research framework by incorporating elements from Ford’s evidence-based theoretical model to guide the following proposed study aims: 1) To elucidate barriers and facilitators to consistent identification and documentation of smoking status to promote LCS uptake among Hispanic current and former smokers; 2) To assess feasibility, acceptability, and reach of the digital delivery of an educational video to promote LCS uptake among Hispanic current and former smokers; 3) To explore the effect of the digital delivery of the educational video to increase interest, intent, and scheduling of LCS uptake among Hispanic current and former smokers. Training: The career development plan will allow Dr. Flores to develop expertise in tailoring LCS interventions among Hispanic communities by completing training objectives in three areas: 1) mixed methods to inform health interventions; 2) community-based participatory research to guide outreach interventions; 3) digital interventions tailored to promote LCS uptake among Hispanic communities. Advanced coursework, a resource-rich institutional environment, and the proposed research study will support these training objectives. Mentorship: A team of expert mentors, including Dr. Elyse R. Park (primary mentor),Dr. Ruth C. Carlos (co-mentor), and Dr. Kelly E Irwin (co-mentor), and scientific advisors including Dr. Jennifer Haas, Dr. Nancy Rigotti, Dr. Giselle Perez, Dr. Jo-Anne Shepard, Dr. Joseph Betancourt, and Dr. Nathaniel Mercaldo will guide Dr. Flores’ training and research efforts for the duration of the award. Impact: The successfulcompletion of this proposed K08 award will provide Dr. Flores with the rigorous training and research expertise that will provide high-quality data to inform an NCI R01. It will also serve as a foundation for him to become a leading independent investigator developing novel interventions to overcome disparities and advance equity in lung cancer outcomes among Hispanics and other vulnerable populations.

项目总结候选人：NCI K08指导临床科学家研究生涯的重新提交促进多样性发展奖将Efrén J.Flores，MD描述为一位很好的- 能够顺利完成拟议的培训目标和研究目标。弗洛雷斯博士的背景作为一名西班牙裔内科医生和临床研究人员，一直专注于实现肺部的公平通过开发新的干预措施来增加LCS摄取，通过早期发现癌症结果在西班牙裔和其他弱势群体中。背景资料：肺癌仍居首位美国癌症特有死亡率的原因，拉美裔人患肺癌的结果更差并且由于在演示时处于晚期，死亡率更高。肺癌筛查(LCS)可以通过在西班牙裔、现任和曾经吸烟者中进行早期肺癌检测，拯救了许多人的生命。尽管如此，在没有加大努力的情况下，改善吸烟状况的披露和记录并量身定制促进西班牙裔现任和曾经吸烟者接受LCS的干预措施，这一点作用不大人们将继续在肺癌存活率方面表现出差异。研究目标：基于之前的根据自己的研究经验，弗洛雷斯博士将NIMHD的研究框架福特循证理论模型中的元素，以指导以下拟议的研究目标： 1)阐明一致识别和记录吸烟的障碍和促进者促进西班牙裔现任和曾经吸烟者接受LCS的状况；2)评估可行性，教育视频的数字交付的可接受性和覆盖范围，以促进LCS在西班牙裔现任和曾经吸烟者；3)探索数字传输对教育的影响提高西班牙裔现任和前任LCS使用兴趣、意向和日程安排的视频吸烟者。培训：职业发展计划将使弗洛雷斯博士能够发展裁剪方面的专业知识通过完成以下三个领域的培训目标，在拉美裔社区中开展LCS干预：1) 提供卫生干预信息的混合方法；2)以社区为基础的参与性研究指导外展干预措施；3)为促进西班牙裔接受LCS而量身定做的数字干预措施社区。先进的课程，资源丰富的制度环境，以及拟议的研究性学习将支持这些培训目标。导师制：由专家导师组成的团队，包括Elyse R.Park博士(主要导师)、Ruth C.Carlos博士(共同导师)和Kelly E Irwin博士 (共同导师)，以及包括Jennifer Haas博士、Nancy Rigotti博士、Giselle Perez博士在内的科学顾问，乔-安妮·谢泼德博士、约瑟夫·贝当古博士和纳撒尼尔·梅卡尔多博士将指导弗洛雷斯博士的在获奖期间的培训和研究工作。影响：成功完成这项工作拟议的K08奖项将为弗洛雷斯博士提供严格的培训和研究专业知识，提供高质量的数据为NCI R01提供信息。这也将成为他成为领先的独立调查人员，开发新的干预措施，以克服差异和在拉美裔和其他弱势群体中促进肺癌结果的公平性。