Health Opportunities & Promoters of Equitable Screening for Lung Cancer (Hopes for Lung Cancer)

健康机会

• 批准号: 10591639
• 负责人: Efren Flores
• 金额: $ 28.08万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-02-03 至 2028-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10591639
• 关键词: Address; Area; Award; Awareness; COVID-19; Cancer Etiology; Charge; Clinic; Clinical; Collaborations; Communities; Community Health; Community Networks; Data; Dedications; Development Plans; Disclosure; Disparity; Documentation; Early Diagnosis; Education; Education and Outreach; Educational Intervention; Electronic Health Record; Electronic Mail; Elements; Eligibility Determination; Environment; Equity; Focus Groups; Foundations; Fright; Guidelines; Health; Healthcare Systems; Hispanic; Hispanic Populations; Hospitals; Individual; Institution; Intervention; K-Series Research Career Programs; Leadership; Malignant neoplasm of lung; Mental Health; Mentors; Mentorship; Methods; Modality; Modeling; National Institute on Minority Health and Health Disparities; Not Hispanic or Latino; Outcome; Participant; Patient Participation; Patients; Physicians; Population; Positioning Attribute; Provider; Publishing; Radiology Specialty; Research; Research Personnel; Resources; Schedule; Scientist; Smoker; Smoking Status; Surveys; Text Messaging; Theoretical model; Training; Training Support; Underserved Population; United States Preventative Services Task Force; Vulnerable Populations; Work; acceptability and feasibility; cancer health disparity; cancer survival; career; career development; community based participatory research; community partnership; cost; digital delivery; digital health; digital intervention; evidence base; experience; former smoker; health record; hispanic community; improved; innovation; interest; intervention delivery; intervention effect; low socioeconomic status; lung basal segment; lung cancer screening; mortality; novel; outreach; patient portal; pilot trial; prevent; promoter; research study; satisfaction; screening guidelines; screening participation; severe mental illness; smoking cessation; social culture; trial enrollment; uptake

PROJECT SUMMARY Candidate: This resubmission for the NCI K08 Mentored Clinical Scientist Research Career Development Award to Promote Diversity describes Efrén J. Flores, MD as a candidate who is well- positioned to successfully complete the proposed training objectives and research aims. Dr. Flores’ background as a Hispanic physician and clinical researcher has focused on achieving equity in lung cancer outcomes through early detection by developing novel interventions to increase LCS uptake among Hispanic and othervulnerable populations. Background: Lung cancer remains the leading cause of cancer-specific mortality in theUS, and Hispanics experience worse lung cancer outcomes and die at higher rates due to advanced stage at presentation. Lung cancer screening (LCS) can save many lives through early lung cancer detection among Hispanic current and former smokers. Still, without increasing efforts to improve smoking status disclosure and documentation and tailored interventions to promote LCS uptake among Hispanic current and former smokers, this underserved population will continue to demonstrate disparities in lung cancer survival. Study aims: Based on prior research experience, Dr. Flores has adapted the NIMHD research framework by incorporating elements from Ford’s evidence-based theoretical model to guide the following proposed study aims: 1) To elucidate barriers and facilitators to consistent identification and documentation of smoking status to promote LCS uptake among Hispanic current and former smokers; 2) To assess feasibility, acceptability, and reach of the digital delivery of an educational video to promote LCS uptake among Hispanic current and former smokers; 3) To explore the effect of the digital delivery of the educational video to increase interest, intent, and scheduling of LCS uptake among Hispanic current and former smokers. Training: The career development plan will allow Dr. Flores to develop expertise in tailoring LCS interventions among Hispanic communities by completing training objectives in three areas: 1) mixed methods to inform health interventions; 2) community-based participatory research to guide outreach interventions; 3) digital interventions tailored to promote LCS uptake among Hispanic communities. Advanced coursework, a resource-rich institutional environment, and the proposed research study will support these training objectives. Mentorship: A team of expert mentors, including Dr. Elyse R. Park (primary mentor),Dr. Ruth C. Carlos (co-mentor), and Dr. Kelly E Irwin (co-mentor), and scientific advisors including Dr. Jennifer Haas, Dr. Nancy Rigotti, Dr. Giselle Perez, Dr. Jo-Anne Shepard, Dr. Joseph Betancourt, and Dr. Nathaniel Mercaldo will guide Dr. Flores’ training and research efforts for the duration of the award. Impact: The successfulcompletion of this proposed K08 award will provide Dr. Flores with the rigorous training and research expertise that will provide high-quality data to inform an NCI R01. It will also serve as a foundation for him to become a leading independent investigator developing novel interventions to overcome disparities and advance equity in lung cancer outcomes among Hispanics and other vulnerable populations.

项目摘要 候选人：重新提交NCI K 08指导临床科学家研究生涯 发展奖，以促进多样性描述埃夫伦J.弗洛雷斯，医学博士作为一个候选人谁是好- 能够顺利完成拟定的培训目标和研究目标。弗洛雷斯博士 作为一名西班牙裔医生和临床研究人员，他的背景是致力于实现肺的公平性， 通过开发新的干预措施来增加LCS的摄取，通过早期检测来实现癌症结局 in Hispanic西班牙裔and othervulnerable弱势populations人群.背景：肺癌仍然是 是美国癌症特异性死亡率的主要原因，西班牙裔肺癌预后更差 并且由于在呈现时的晚期而以更高的比率死亡。肺癌筛查（LCS）可以 通过在西班牙裔当前和以前的吸烟者中进行早期肺癌检测，挽救了许多生命。 尽管如此，如果不加大努力改善吸烟状况的披露和记录， 在西班牙裔当前和以前的吸烟者中促进LCS摄取的干预措施， 人群将继续表现出肺癌生存率的差异。研究目的：基于先前 弗洛雷斯博士根据自己的研究经验， 来自福特循证理论模型的元素，以指导以下拟议的研究目标： 1)阐明一致识别和记录吸烟的障碍和促进因素 促进西班牙裔当前和以前吸烟者中LCS摄取的状况; 2）评估可行性， 可接受性，以及教育视频的数字化交付的覆盖范围，以促进LCS在 西班牙裔当前和以前的吸烟者; 3）探索教育数字化交付的效果 视频，以增加兴趣，意图，并安排LCS吸收西班牙裔当前和以前 吸烟者。培训：职业发展计划将使弗洛雷斯博士能够发展裁缝方面的专业知识 通过完成三个领域的培训目标，对西班牙裔社区进行LCS干预： 混合方法，为健康干预提供信息; 2）以社区为基础的参与性研究， 外展干预; 3）数字干预，以促进西班牙裔之间的LCS吸收量身定制 社区.先进的课程，资源丰富的制度环境，以及拟议的 研究将支持这些培训目标。导师：一个专家导师团队， 包括Elyse R.博士Park（初级导师），Ruth C.卡洛斯（共同导师）和凯利E欧文博士 （共同导师）和科学顾问，包括Jennifer哈斯博士，Nancy Rigotti博士，Giselle Perez博士， 博士Jo-Anne谢泼德、Joseph Betancourt博士和Nathaniel Mercaldo博士将指导弗洛雷斯博士 奖励期间的培训和研究工作。影响：成功完成这项工作 拟议的K 08奖将为弗洛雷斯博士提供严格的培训和研究专业知识， 提供高质量的数据以通知NCI R 01。这也将成为他成为 一位领先的独立调查员，开发新的干预措施，以克服差距， 促进西班牙裔和其他弱势群体肺癌结果的公平性。