Infrastructure and Opportunity Fund Management Core

IOFM核心：基础设施和机会管理核心 项目摘要 NIH人类免疫学合作中心（CCHI）计划旨在促进以下方面的研究： 通过为8-10个项目提供资金以及为试点项目提供额外的财政支持， 项目、新资源和试剂开发和/或跨项目协作。这些 通过基础设施和机会基金提供的资金，发展奖励成为可能 (IOF)格兰特.基础设施和机会基金赠款授予支持的计划之一 通过CCHI U19机制。获得基础设施和机会基金赠款的机构 基础设施和机会基金管理核心（IOFMC）。的 IOFMC与NIH项目官员和CCHI科学指导委员会合作，征求、审查和 将基础设施和机会基金作为子基金分配给IOFMC母机构的研究人员 以及在其他机构工作的调查人员，他们在许多情况下是其他受资助机构的成员， CCHI合作中心。IOFMC负责对分授合同进行行政监督， 确保获奖者和他们工作的机构符合所有 适用的州、NIH和联邦法规，并且分裁决的收费是合理和允许的。 最后，IOFMC还必须向NIH提供关于所授予分包合同的年度财务报告。主要 UAB国际飞行管理委员会的目标是建立一个管理子合同项目的行政结构 从申请请求（RFA）阶段，到授予前和授予后流程，以及通过授予关闭- 出和报告阶段。为了实现这一目标，我们将：（一）协调IOF项目的申请， （ii）建立分包合同，将IOF开发和试点项目赠款分配给项目 （三）其他机构的领导人;（三）对这些子奖项进行行政和财政监督;以及（四）担任 作为IOF获奖者，CCHI指导委员会和NIH之间的沟通界面。 UAB IOFMC成功和及时完成这些目标将使NIH能够利用 知识、基础设施和独特的试剂/样品，这些都存在于CCHI网络机构中， 推进CCHI计划的总体科学目标。

IOFM Core: Infrastructure and Opportunities Management Core Project Summary The NIH Cooperative Centers on Human Immunology (CCHI) program was designed to promote research in human immunology by providing funding for 8-10 Programs as well as additional financial support for pilot projects, new resource and reagent development and/or cross-program collaborative efforts. These developmental awards are made possible through funding provided by the Infrastructure and Opportunity Fund (IOF) grant. The Infrastructure and Opportunity Fund grant is awarded to one of the Programs supported through the CCHI U19 mechanism. The institution that receives the Infrastructure and Opportunity Funds grant is responsible for establishing an Infrastructure and Opportunity Fund Management Core (IOFMC). The IOFMC works with the NIH Program officers and the CCHI scientific steering committee to solicit, review and distribute Infrastructure and Opportunity Funds as subawards to researchers at the IOFMC parent institution and investigators working at other institutions, who are, in many cases, members of one of the other funded CCHI cooperative centers. The IOFMC is responsible for administrative oversight of the subawards and for ensuring that the recipient of the award and the institution in which they work are in compliance with all applicable state, NIH and federal regulations and that charges to the subaward are reasonable and allowable. Finally, the IOFMC must also provide annual financial reports on the awarded subcontracts to NIH. The major goal of the UAB IOFMC will be to establish an administrative structure that will manage the subaward program from the request for applications (RFA) stage, to the pre- and post-award process, and through the grant close- out and reporting phase. In order to meet this goal, we will: (i) coordinate the IOF project application and selection process; (ii) establish subcontracts to distribute IOF development and pilot project grants to Project Leaders at other institutions; (iii) provide administrative and fiscal oversight of these subawards; and (iv) serve as the communications interface between IOF awardees, the CCHI steering committee and the NIH. Successful and timely completion of these objectives by the UAB IOFMC will allow the NIH to leverage the intellectual, infrastructure and unique reagents/samples that are present in the CCHI network institutions to advance the overall scientific goals of the CCHI program.