Informing alcohol policy: The impact of evidence-based alcohol warnings on consumption

告知酒精政策：基于证据的酒精警告对消费的影响

• 批准号: 10565120
• 负责人: Anna H Grummon
• 金额: $ 57.23万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-20 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10565120
• 关键词: 2 arm randomized control trial; Accounting; Address; Adopted; Adult; Age; Alcohol consumption; Alcohols; American; Authorization documentation; Back; Behavior; Cause of Death; Cessation of life; Communication; Consumption; Data; Development; Disease; Education; Effectiveness; Elements; Ensure; Equation; Evidence based practice; Exposure to; Federal Government; Gender; Guidelines; Health; Home; Injury; Interview; Label; Laboratories; Legal; Measures; Mediation; Mediator; Meta-Analysis; Methods; Modeling; Participant; Policies; Policy Making; Probability Samples; Product Labeling; Protocols documentation; Randomized; Recommendation; Research; Risk; Rotation; Sampling; Side; Smoking; Speed; Subgroup; Surveys; Testing; Time; United States; Update; Visit; Woman; Work; alcohol risk; arm; authority; behavior influence; binge drinking; cancer type; design; diaries; disability; drinking; evidence base; experimental analysis; experimental study; health warning; hypertensive heart disease; innovation; insight; men; primary outcome; psychologic; public policy on alcohol; randomized trial; recruit; secondary outcome; warning label

PROJECT ABSTRACT Nearly 1 in 3 American adults exceed the recommended limit for alcohol consumption, increasing their risk of health problems including hypertensive heart disease, injuries, and several types of cancer. Most adults are not aware of the harms of alcohol consumption. Evidence-based warnings on alcohol containers that are displayed prominently on the front of the package, include pictorial elements such as icons, and rotate their content over time could inform consumers and discourage unhealthy alcohol consumption. The overarching objective of this proposal is to evaluate the impact of evidence-based alcohol warnings on alcohol consumption. In Aim 1, we will use existing research and expert review to optimize warning statements describing the health harms of alcohol consumption. We will then test an array of evidence-based warnings in a randomized experiment with a nationally representative sample of 910 adult regular alcohol consumers. The main product of Aim 1 will be the selection of 4 evidence-based warnings that participants endorse as effective for use in Aim 2. In Aim 2, we will evaluate the impact of these evidence-based alcohol warnings on alcohol consumption in a longitudinal RCT. We will recruit 786 adult regular alcohol consumers. Participants will be randomly assigned to a warnings arm or a control arm. In a 4-week study, participants in the warnings arm will receive the 4 unique evidence-based warnings affixed to their alcohol containers, allocated in random order. In the control arm, no new labels will be applied. We will assess whether the evidence-based alcohol warnings reduce number of drinks consumed (measured using daily diaries) and examine whether this effect varies by baseline alcohol use, gender, age, and education. We will also evaluate how warnings influence potential psychological mediators (measured in weekly surveys). The final product of Aim 2 will be an estimate of the impact of evidence-based alcohol warnings on alcohol consumption. In Aim 3, we will validate a model of how alcohol warnings influence alcohol consumption. We will conduct in-depth interviews with participants in the warnings arm of Aim 2’s RCT to elicit insights about the mechanisms through which the trial warnings influenced their behavior. Then, we will apply mediation analyses to the longitudinal daily diary and survey data collected in Aim 2’s RCT to identify mediators of the impact of the trial warnings on alcohol consumption. The final product of Aim 3 will be a model of how evidence-based alcohol warnings influence alcohol consumption. This research is responsive to NOT-AA-21-028 by conducting causal analyses of an alcohol-reduction policy and advancing methods by implementing an innovative RCT with naturalistic exposure to warnings. Our findings will create an evidence base to inform development of effective alcohol warnings as well as other communication campaigns. Ultimately, new evidence-based alcohol warnings could reduce unhealthy alcohol consumption and address rising rates of alcohol-attributable disease and death in the US and globally.

项目摘要 近三分之一的美国成年人超过了酒精消费的建议限制，增加了他们的风险。 健康问题，包括高血压性心脏病、受伤和几种癌症。大多数成年人 没有意识到饮酒的危害。酒精容器上的循证警告 在包装的正面突出显示，包括图标等图形元素，并旋转其 随着时间的推移，酒精含量可以告知消费者，并阻止不健康的酒精消费。总体 该提案的目的是评估循证酒精警告对酒精的影响 消费在目标1中，我们将利用现有的研究和专家评审来优化警告声明 描述饮酒对健康的危害。然后，我们将测试一系列基于证据的警告， 一项随机实验，对910名成年饮酒者进行了全国代表性的抽样。的 目标1的主要产品将是选择参与者认可为有效的4个循证警告 用于目标2。在目标2中，我们将评估这些基于证据的酒精警告对酒精的影响 纵向RCT中的消耗量。我们将招募786名成年常规饮酒者。参与者将被 随机分配到警告组或对照组。在为期4周的研究中，警告组的参与者将 收到4个独特的循证警告贴在他们的酒精容器，随机分配的顺序。在 对照组，将不应用新标签。我们将评估基于证据的酒精警告是否 减少饮酒量（使用每日日记测量），并检查这种影响是否因 基线酒精使用，性别，年龄和教育。我们还将评估警告如何影响潜在的 心理调解人（在每周调查中测量）。目标2的最终产品将是对 基于证据的酒精警告对酒精消费的影响。在目标3中，我们将验证如何 酒精警告影响酒精消费。我们将对参与者进行深入采访， Aim 2随机对照试验的警告臂，以了解试验警告的机制。 影响了他们的行为。然后，我们将中介分析应用于纵向日记和调查数据 Aim 2的随机对照试验中收集的数据，以确定试验警告对酒精消费影响的介导因素。的 目标3的最终产品将是一个基于证据的酒精警告如何影响酒精消费的模型。 本研究通过对酒精减少进行因果分析来响应NOT-AA-21-028 通过实施一项创新的随机对照试验，自然地暴露在警告中，来制定政策和推进方法。 我们的研究结果将建立一个证据基础，为有效的酒精警告以及其他 宣传运动。最终，新的基于证据的酒精警告可以减少不健康的酒精 消费和解决美国和全球酒精相关疾病和死亡率上升的问题。