R38 Stanford Integrated Cardiovascular/Pulmonary Residency Research Training Program

项目摘要 斯坦福大学医学院是生物医学研究领域无与伦比的卓越之地， 心血管和肺部医学领域的创新领导者。斯坦福大学综合 本提案中描述的心血管/肺科住院医师研究培训计划将提供 研究机会，为有才华的个人从事住院医师阶段的医疗培训。的 该计划将吸引来自斯坦福大学内科，儿科， 心胸外科和放射学，并将其放置在基础，转化和临床研究实验室 附属于斯坦福大学心血管研究所（CVI），获得持续1-2年的指导研究经验 年完成临床培训后，成功的住院研究者将有资格参加K38 资助继续研究工作。该计划还将满足心胸外科的特殊需求。 外科和麻醉学住院医师项目，要求受训者将一段时间 研究，并将提供新的和宝贵的机会，在其他专业的居民。研究 拟议中的StARR计划的导师将是斯坦福大学CVI的成员，该组织提供了一个独特的平台 培养下一代基础科学家和转化科学家。主要研究项目在 CVI分为心脏疾病、血管疾病和肺部疾病类别，纳入了以下学科 基因组学、蛋白质组学和生物信息学;细胞和分子生物学;成像;生物工程;以及 人口科学CVI科学家对心血管疾病背后的机制有着共同的兴趣， 肺医学，并共同努力创造新的治疗，再生，和预防 心血管和肺部疾病的治疗方法。此外，CVI已经提供了多方面的 教育和职业发展计划，以提高StARR受训人员的经验， 准备他们推出成功的职业生涯作为未来的临床科学家与成功的学术生涯。

PROJECT SUMMARY Stanford University School of Medicine is a site of unparalleled excellence in biomedical research and is a innovative leader in the fields of cardiovascular and pulmonary medicine. The Stanford Integrated Cardiovascular/Pulmonary Residency Research Training Program described in this proposal will provide research opportunities for talented individuals engaged in the residency stage of their medical training. The program will draw resident investigators from the Stanford residency programs in Internal Medicine, Pediatrics, Cardiothoracic Surgery, and Radiology, and place them in basic, translational, and clinical research laboratories affiliated with the Stanford Cardiovascular Institute (CVI) for a mentored research experience lasting 1-2 years. Upon completion of their clinical training, successful resident-investigators would be eligible for K38 funding to support continued research efforts. This program would also fill a particular need of the Cardiothoracic Surgery and Anesthesiology residency programs, which require their trainees to dedicate a period of their time to research and would provide new and valuable opportunities for residents in other specialties. Research mentors for the proposed StARR program would be members of the Stanford CVI, which offers a unique platform by which to train the next generation of basic and translational scientists. Major research programs within the CVI are organized into Cardiac, Vascular, and Pulmonary disease categories, incorporating the disciplines of Genomics, Proteomics and Bioinformatics; Cellular and Molecular Biology; Imaging; Bioengineering; and Population Science. CVI scientists share a common interest in the mechanisms behind cardiovascular and pulmonary medicine, and work together towards creating novel therapeutic, regenerative, and preventative approaches to cardiovascular and pulmonary diseases. Furthermore, the CVI already offers multifaceted educational and career development programs that would enhance the experience of StARR trainees and prepare them to launch successful careers as future clinician scientists with successful academic careers.