R38 Stanford Integrated Cardiovascular/Pulmonary Residency Research Training Program

R38 斯坦福综合心血管/肺部住院医师研究培训计划

• 批准号: 10565903
• 负责人: Michael Peter Fischbein
• 金额: $ 32.86万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-02-10 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10565903
• 关键词: Achievement; Address; Anesthesiology; Basic Science; Bioinformatics; Biomedical Engineering; Biomedical Research; Blood Vessels; Cardiovascular Diseases; Cardiovascular system; Career Choice; Categories; Cause of Death; Cellular biology; Cessation of life; Clinical; Clinical Research; Communities; Dedications; Development; Discipline; Doctor of Philosophy; Education; Educational Curriculum; Educational workshop; Eligibility Determination; Ensure; Ethnic Origin; Evaluation; Faculty; Funding; Future; Gender; Genomics; Goals; Grant; Heart Diseases; Image; Individual; Internal Medicine; K-Series Research Career Programs; Knowledge; Laboratories; Laboratory Research; Lung; Lung diseases; Medical; Medical Education; Medicine; Mentors; Mentorship; Molecular Biology; Monitor; Obesity; Operative Surgical Procedures; Pediatrics; Physicians; Population Sciences; Prevention; Prevention strategy; Problem Solving; Program Description; Program Development; Proteomics; Pulmonology; Race; Radiology Specialty; Records; Religion; Research; Research Activity; Research Personnel; Research Support; Research Technics; Research Training; Residencies; Risk Factors; Science; Scientist; Secure; Site; Statistical Data Interpretation; Structure; Talents; Teacher Professional Development; Therapeutic; Time; Tobacco use; Training; Training Programs; Translational Research; Underrepresented Minority; United States; Universities; Vascular Diseases; Woman; Women' s Health; Work; Writing; cardiovascular health; career; career development; clinical training; cohort; disability; experience; faculty mentor; innovation; interest; lung health; medical schools; medical specialties; meetings; member; next generation; novel strategies; novel therapeutics; population health; programs; recruit; regenerative; responsible research conduct; role model; skill acquisition; student mentoring; training opportunity; translational scientist

PROJECT SUMMARY Stanford University School of Medicine is a site of unparalleled excellence in biomedical research and is a innovative leader in the fields of cardiovascular and pulmonary medicine. The Stanford Integrated Cardiovascular/Pulmonary Residency Research Training Program described in this proposal will provide research opportunities for talented individuals engaged in the residency stage of their medical training. The program will draw resident investigators from the Stanford residency programs in Internal Medicine, Pediatrics, Cardiothoracic Surgery, and Radiology, and place them in basic, translational, and clinical research laboratories affiliated with the Stanford Cardiovascular Institute (CVI) for a mentored research experience lasting 1-2 years. Upon completion of their clinical training, successful resident-investigators would be eligible for K38 funding to support continued research efforts. This program would also fill a particular need of the Cardiothoracic Surgery and Anesthesiology residency programs, which require their trainees to dedicate a period of their time to research and would provide new and valuable opportunities for residents in other specialties. Research mentors for the proposed StARR program would be members of the Stanford CVI, which offers a unique platform by which to train the next generation of basic and translational scientists. Major research programs within the CVI are organized into Cardiac, Vascular, and Pulmonary disease categories, incorporating the disciplines of Genomics, Proteomics and Bioinformatics; Cellular and Molecular Biology; Imaging; Bioengineering; and Population Science. CVI scientists share a common interest in the mechanisms behind cardiovascular and pulmonary medicine, and work together towards creating novel therapeutic, regenerative, and preventative approaches to cardiovascular and pulmonary diseases. Furthermore, the CVI already offers multifaceted educational and career development programs that would enhance the experience of StARR trainees and prepare them to launch successful careers as future clinician scientists with successful academic careers.

项目总结 斯坦福大学医学院是一个在生物医学研究方面无与伦比的优秀网站，是 心血管和肺部医学领域的创新领导者。斯坦福大学的整合 本提案中描述的心血管/肺住院医师研究培训计划将提供 在医学培训的住院医生阶段，为有才华的个人提供研究机会。这个 该项目将吸引斯坦福大学内科、儿科、 心胸外科和放射学，并将它们放在基础、翻译和临床研究实验室 隶属于斯坦福大学心血管研究所(CVI)，提供为期1-2年的指导研究体验 好几年了。在完成临床培训后，成功的住院医师将有资格参加K38 用于支持持续研究工作的资金。该计划还将满足心胸外科的特殊需求 外科和麻醉学住院医师计划，这要求他们的实习生花一段时间 研究并将为其他专业的住院医生提供新的宝贵机会。研究 提议的STARR项目的导师将是斯坦福CVI的成员，该项目提供了一个独特的平台 以此来培养下一代基础和转化型科学家。主要研究项目包括 CVI分为心脏、血管和肺部疾病类别，包含以下学科 基因组学、蛋白质组学和生物信息学；细胞和分子生物学；成像；生物工程；以及 人口科学。CVI的科学家对心血管和心血管疾病背后的机制有着共同的兴趣 肺部医学，共同努力创造新的治疗、再生和预防 心血管和肺部疾病的治疗方法。此外，CVI已经提供了多方面的 教育和职业发展计划，将增强STARR实习生和 让他们做好准备，成为拥有成功学术生涯的未来临床科学家，开始成功的职业生涯。

项目成果

Revised Heart Allocation Policy Improved Waitlist Mortality and Waiting Time With Maintained Outcomes in En-Bloc Heart-Lung Transplant Candidates and Recipients.

• DOI: 10.3389/ti.2023.11956
• 发表时间: 2023
• 期刊: Transplant international : official journal of the European Society for Organ Transplantation

Diminishing Basic Science Research Experience Among United States Cardiothoracic Surgery Trainees.

• DOI: 10.1016/j.jss.2022.06.020
• 发表时间: 2022-11
• 期刊: JOURNAL OF SURGICAL RESEARCH
• 影响因子: 2.2
• 作者: Wang, Hanjay;Bajaj, Simar S.;Manjunatha, Keerthi;Yu, Maggie M.;Obafemi, Oluwatomisin O.;Williams, Kiah M.;Boyd, Jack H.
• 通讯作者: Boyd, Jack H.

An automated line-clearing chest tube system after cardiac surgery.

心脏手术后自动清理胸管系统。

• DOI: 10.1016/j.xjon.2022.02.020
• 发表时间: 2022-06
• 期刊: JTCVS open
• 作者: Obafemi, Oluwatomisin Olurotimi;Wang, Hanjay;Bajaj, Simar S;O'Donnell, Christian T;Elde, Stefan;Boyd, Jack H
• 通讯作者: Boyd, Jack H

Biomechanics and clinical outcomes of various conduit configurations in valve sparing aortic root replacement.

• DOI: 10.21037/acs-2023-avs2-0068
• 发表时间: 2023-07-31
• 期刊: ANNALS OF CARDIOTHORACIC SURGERY
• 影响因子: 3.1
• 作者: Zhu, Yuanjia;Park, Matthew H.;Pandya, Pearly K.;Stark, Charles J.;Mullis, Danielle M.;Walsh, Sabrina K.;Kim, Joo Young;Wu, Catherine A.;Baccouche, Basil M.;Lee, Seung Hyun;Baraka, Abakar S.;Joo, Hyunchel;Yajima, Shin;Elde, Stefan;Woo, Y. Joseph
• 通讯作者: Woo, Y. Joseph

Outcomes after concomitant arch replacement at the time of aortic root surgery.

主动脉根部手术同时进行弓形置换后的结果。

• DOI: 10.1016/j.xjon.2022.12.014
• 发表时间: 2023
• 期刊: JTCVS open
• 作者: Krishnan,Aravind;Dalal,AlexR;Pedroza,AlbertJames;Nakamura,Ken;Yokoyama,Nobu;Tognozzi,Emily;Woo,YJoseph;Fischbein,Michael;MacArthur,JohnWard
• 通讯作者: MacArthur,JohnWard