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Rheumatic and Autoimmune Diseases in Minority Communities

少数民族社区的风湿病和自身免疫性疾病

基本信息

批准号：
10928014
负责人：
Sarfaraz Hasni
金额：
$ 42.68万
依托单位：
NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10928014
关键词：
Adult Area Arthritis Assessment tool Autoimmune Autoimmune Diseases COVID-19 Clinic Clinical Collection Complementary and alternative medicine Data Dedications Diagnosis Disease District of Columbia Evaluation Goals Immune Improve Access Informed Consent Intervention Methods Minority Groups Musculoskeletal National Institute of Arthritis, and Musculoskeletal, and Skin Diseases Neighborhood Health Center Observational Study Outcome Outcome Assessment Patient Outcomes Assessments Patient Self-Report Patients Process Research Research Personnel Research Support Rheumatism Rheumatoid Arthritis Serology Site Standardization Symptoms Systemic Lupus Erythematosus Vaccines Vascular Diseases Viral Washington Yoga barrier to care cohort disease phenotype ethnic difference ethnic minority experience health care disparity health disparity improved indexing metropolitan minority communities outreach pediatric patients primary care provider response social health determinants standard of care systemic autoimmunity systemic inflammatory response

项目摘要

This project studies the clinical presentation of rheumatic diseases in an underserved, largely ethnic minority community in the Washington, D.C. metropolitan area. Through the NIAMS Community Health Center, subjects with rheumatic complaints are evaluated and provide clinicians with first-hand experience in understanding ethnic differences in autoimmune disease phenotypes as well as barriers to care. This project has supported research on cultural differences in understanding standardized self-report outcome assessment tools, determination of clinically important improvements in rheumatoid arthritis, use of complementary and alternative medicine in patients with rheumatic symptoms, acceptability of yoga as a treatment for arthritis by minority individuals and understanding of the research process and informed consent among ethnic minorities. In addition, researchers have examined interventions to improve the referral process between primary care providers and subspecialists. Serological studies are currently underway to examine immune abnormalities in patients with rheumatoid arthritis and systemic lupus erythematosus. We have been actively involved in an observational study to characterize how COVID-19 modulates systemic inflammation, autoimmune features and vasculopathy in adult and pediatric patients with a prior diagnosis of systemic autoimmunity, and their overall outcomes including response to antiviral treatments or vaccines. We have opened an additional clinic site in Northeast Washington D.C. to improve access and increase our outreach to the minority community with rheumatic diseases. We are starting collection of disease activity indices and patient reported outcome data including social determinants of health to better understand healthcare disparities in minority communities.

该项目研究了华盛顿，华盛顿特区大都市地区一个服务不足的、主要是少数民族社区的风湿性疾病的临床表现。通过NIAMS社区健康中心，对风湿病患者进行评估，并为临床医生提供了解自身免疫性疾病表型种族差异以及护理障碍的第一手经验。该项目支持开展以下方面的文化差异研究：理解标准化自我报告结果评估工具、确定类风湿性关节炎的临床重要改善、在有风湿症状的患者中使用补充和替代药物、少数民族个人接受瑜伽治疗关节炎以及少数民族对研究过程和知情同意的理解。此外，研究人员还研究了改善初级保健提供者和专科医生之间转诊过程的干预措施。目前正在进行血清学研究，以检查类风湿关节炎和系统性红斑狼疮患者的免疫异常。我们积极参与了一项观察性研究，以描述COVID-19如何调节既往诊断为全身性自身免疫的成人和儿童患者的全身炎症、自身免疫特征和血管病变，以及他们的总体结局，包括对抗病毒治疗或疫苗的反应。我们在东北部华盛顿特区开设了一个额外的诊所，以改善和增加我们对患有风湿性疾病的少数民族社区的接触。我们正在开始收集疾病活动指数和患者报告的结果数据，包括健康的社会决定因素，以更好地了解少数民族社区的医疗保健差异。

项目成果

期刊论文数量（8）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

A qualitative approach exploring the acceptability of yoga for minorities living with arthritis: 'Where are the people who look like me?'.

DOI：
10.1016/j.ctim.2017.02.006
发表时间：
2017-04
期刊：
Complementary therapies in medicine
影响因子：
3.6
作者：
Middleton KR;Magaña López M;Haaz Moonaz S;Tataw-Ayuketah G;Ward MM;Wallen GR
通讯作者：
Wallen GR

Validating English- and Spanish-language patient-reported outcome measures in underserved patients with rheumatic disease.