Young Empowered Scientists for ContinUed Research Engagement (YES for CURE)
赋权年轻科学家继续参与研究(CURE 是)
基本信息
- 批准号:10929573
- 负责人:
- 金额:$ 20万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-09-19 至 2024-08-31
- 项目状态:已结题
- 来源:
- 关键词:Academic TrainingAddressAreaAwarenessBachelor&aposs DegreeBostonCancer BurdenCancer CenterCancer ScienceClinicalCommunitiesCuriositiesDiscipline of NursingEconomically Deprived PopulationEducationEducational CurriculumEducational process of instructingEthicsFacultyFamilyFundingGoalsHealthHealth ProfessionalHigh School StudentIndividualInstitutionKnowledgeMalignant NeoplasmsMeasurableMentorsNCI Center for Cancer ResearchOutcomeParticipantPathway interactionsPopulationPreparationProcessProfessional CompetenceResearchResearch Project GrantsSTEM curriculumSTEM fieldSTEM researchScienceScience, Technology, Engineering and MathematicsScientistStudentsSupervisionTalentsThinkingTrainingUnderrepresented MinorityUnderrepresented PopulationsUnited StatesUniversitiesWorkanticancer researchcancer health disparitycareercommunity engagementcultural competencecurriculum developmentdisadvantaged backgroundeconomic disparityempowermentexperiencegraduate schoolhigh schoolhigh school programimprovedinnovationinterestoutreachprogramsresearch in practiceskill acquisitionskillssocioeconomic disadvantagesuccesssummer researchundergraduate studentuniversity student
项目摘要
Young Empowered Scientists for ContinUed Research Engagement (YES for CURE) Project Summary
Increasing the participation and retention of underrepresented minorities (URMs) in cancer-related
science, technology, engineering, and mathematics (STEM) fields is critical for eliminating cancer disparities
and improving cancer outcomes in the United States. The Dana-Farber/Harvard Cancer Center (DF/HCC)
requests funding to address the shortfall of URMs and socioeconomically disadvantaged individuals engaged
in cancer research related careers. Our specific goal is to engage the scientific curiosity and promote the
academic success and future research careers of promising young scientists from underrepresented
communities. For over 15 years, DF/HCC has connected high school and college students from
underrepresented populations to the world of cancer research by placing them in real research settings at
Harvard University-affiliated cancer research institutions through a continuously funded P30 CURE
Supplement ending this year. More than two thirds of our alumni have gone on to complete STEM degrees and
to successfully pursue science and health-related careers. We propose to continue and expand this work
through the YES for CURE Program, which will provide multi-year cancer and cancer disparities research
experiences and educational programming for high school students and undergraduates in the Boston area.
Each year, 40 talented high school and college students from the Boston area, selected through a competitive
application process, will engage in a program comprised of three interrelated components: (1) mentored, full-
time summer research experiences in DF/HCC cancer research labs; (2) a year-round innovative Strategies for
Science Success curriculum focused on building scientific and professional competency; and (3) community
and family engagement and outreach geared towards developing a supportive, informed, and engaged
network who will nurture and empower program participants to achieve academic success and pursue careers
in scientific research. These three components will be woven together into a comprehensive, multi-year
experience that will prime participants for further academic training and careers in scientific research and the
pursuit of further, program-independent research experiences. Further, we will leverage our extensive student
tracking expertise to assess the impact of the YES for CURE Program on student interest in and preparation
for cancer and cancer disparities research careers and their scientific skills and concepts acquisition.
By focusing on students at the beginning of their academic career, we anticipate that the YES for CURE
Program will spark and nurture participant interest in pursuing science degrees and cancer research careers
and increase the retention of underrepresented participants in cancer-related fields.
青年赋权科学家持续参与研究(YES for CURE)
增加代表性不足的少数群体参与和保留与癌症有关的
科学、技术、工程和数学(STEM)领域对于消除癌症差异至关重要
和改善美国的癌症预后。Dana-Farber/哈佛癌症中心(DF/HCC)
要求提供资金,以解决统一资源管理机制和社会经济弱势个人的短缺问题
癌症研究相关的职业。我们的具体目标是激发科学好奇心,
来自代表性不足的有前途的年轻科学家的学术成功和未来的研究事业
社区. 15年来,DF/HCC将高中生和大学生从
通过将他们置于真实的研究环境中,
哈佛大学附属癌症研究机构通过持续资助的P30 CURE
今年结束的补充。超过三分之二的校友继续完成STEM学位,
成功追求科学和健康相关的职业。我们建议继续并扩大这项工作
通过YES for CURE计划,该计划将提供多年的癌症和癌症差异研究
为波士顿地区的高中生和本科生提供经验和教育规划。
每年,40名来自波士顿地区的优秀高中生和大学生,通过竞争性的选拔,
申请过程中,将从事由三个相互关联的组件组成的程序:(1)指导,充分-
在DF/HCC癌症研究实验室的夏季研究经验;(2)全年创新策略,
科学成功课程侧重于培养科学和专业能力;(3)社区
家庭参与和外展,旨在发展一个支持性的,知情的,参与的
网络谁将培育和授权计划参与者实现学术成功和追求职业生涯
在科学研究中。这三个组成部分将交织在一起,成为一个全面的,
经验,将主要参与者进一步的学术培训和科学研究的职业生涯,
追求进一步的,程序独立的研究经验。此外,我们将利用我们广泛的学生
跟踪专业知识,以评估YES for CURE计划对学生兴趣和准备的影响
对于癌症和癌症的差距研究事业和他们的科学技能和概念的收购。
通过关注学生在他们的学术生涯的开始,我们预计,是治愈
该计划将激发和培养参与者对追求科学学位和癌症研究事业的兴趣
并增加癌症相关领域代表性不足的参与者的保留。
项目成果
期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Prevention of type 2 diabetes through remotely administered lifestyle programs: A systematic review.
通过远程管理的生活方式计划预防 2 型糖尿病:系统评价。
- DOI:10.1016/j.cct.2022.106817
- 发表时间:2022
- 期刊:
- 影响因子:2.2
- 作者:Villegas,Valaree;Shah,Alisha;Manson,JoAnnE;Tobias,DeirdreK
- 通讯作者:Tobias,DeirdreK
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James A. DeCaprio其他文献
The DREAM complex: master coordinator of cell cycle-dependent gene expression
DREAM 复合物:细胞周期依赖性基因表达的主要协调者
- DOI:
10.1038/nrc3556 - 发表时间:
2013-07-11 - 期刊:
- 影响因子:66.800
- 作者:
Subhashini Sadasivam;James A. DeCaprio - 通讯作者:
James A. DeCaprio
IMPDH inhibition induces DNA replication stress and ATR sensitivity in Merkel cell carcinoma
IMPDH抑制在默克尔细胞癌中诱导DNA复制应激和ATR敏感性
- DOI:
10.1016/j.isci.2025.112567 - 发表时间:
2025-06-20 - 期刊:
- 影响因子:4.100
- 作者:
Julia L. Schnabel;Thomas C. Frost;Adam C. Wang;Varsha Ananthapadmanabhan;Satvik Gurram;Kara M. Soroko;Prafulla C. Gokhale;James A. DeCaprio - 通讯作者:
James A. DeCaprio
Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC
- DOI:
10.1007/s00262-017-2099-3 - 发表时间:
2017-11-30 - 期刊:
- 影响因子:5.100
- 作者:
Jürgen C. Becker;Andreas Stang;Axel zur Hausen;Nicole Fischer;James A. DeCaprio;Richard W. Tothill;Rikke Lyngaa;Ulla Kring Hansen;Cathrin Ritter;Paul Nghiem;Christopher K. Bichakjian;Selma Ugurel;David Schrama - 通讯作者:
David Schrama
Milademetan is a highly potent MDM2 inhibitor in TP53 wild-type (p53 WT) models of Merkel cell carcinoma (MCC)
- DOI:
10.1016/j.jid.2022.08.004 - 发表时间:
2022-10-01 - 期刊:
- 影响因子:
- 作者:
Varsha Ananthapadmanabhan;Thomas C. Frost;Kara M. Soroko;Aine Knott;Brianna Magliozzi;Prafulla C. Gokhale;Vijaya Tirunagaru;Robert C. Doebele;James A. DeCaprio - 通讯作者:
James A. DeCaprio
Association between treatment center experience and survival after diagnosis of stage I to III Merkel cell carcinoma treated with surgery with or without postoperative radiation therapy
- DOI:
10.1016/j.jaad.2020.10.089 - 发表时间:
2021-03-01 - 期刊:
- 影响因子:
- 作者:
Fallon E. Chipidza;Manisha Thakuria;Jonathan D. Schoenfeld;Ann W. Silk;Paul J. Catalano;Charles H. Yoon;Glenn J. Hanna;James A. DeCaprio;Roy B. Tishler;Danielle N. Margalit - 通讯作者:
Danielle N. Margalit
James A. DeCaprio的其他文献
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{{ truncateString('James A. DeCaprio', 18)}}的其他基金
Identification of Novel Oncogenic Signaling Pathways using Viral Perturbations
利用病毒扰动鉴定新型致癌信号通路
- 批准号:
10460971 - 财政年份:2019
- 资助金额:
$ 20万 - 项目类别:
Identification of Novel Oncogenic Signaling Pathways using Viral Perturbations
利用病毒扰动鉴定新型致癌信号通路
- 批准号:
10411425 - 财政年份:2019
- 资助金额:
$ 20万 - 项目类别:
Identification of Novel Oncogenic Signaling Pathways using Viral Perturbations
利用病毒扰动鉴定新型致癌信号通路
- 批准号:
10664906 - 财政年份:2019
- 资助金额:
$ 20万 - 项目类别:
Identification of Novel Oncogenic Signaling Pathways using Viral Perturbations
利用病毒扰动鉴定新型致癌信号通路
- 批准号:
9816351 - 财政年份:2019
- 资助金额:
$ 20万 - 项目类别:
Identification of Novel Oncogenic Signaling Pathways using Viral Perturbations
利用病毒扰动鉴定新型致癌信号通路
- 批准号:
10222618 - 财政年份:2019
- 资助金额:
$ 20万 - 项目类别:
Young Empowered Scientists for ContinUed Research Engagement (YES for CURE)
赋权年轻科学家继续参与研究(CURE 是)
- 批准号:
9416355 - 财政年份:2017
- 资助金额:
$ 20万 - 项目类别:
PROJECT 1: Merkel Cell Carcinoma, Merkel Cell Polyomavirus and PP2A (James A. DeCaprio)
项目 1:默克尔细胞癌、默克尔细胞多瘤病毒和 PP2A (James A. DeCaprio)
- 批准号:
9981670 - 财政年份:2017
- 资助金额:
$ 20万 - 项目类别:
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