Reagents for Immunologic Analysis of Under-represented Mammalian Models

Integral Molecular公司计划生产一大批针对免疫细胞标记物的泛反应性单克隆抗体（mab），用于9种代表性不足的哺乳动物模型的免疫功能和应答研究。由于某些哺乳动物模型显示出人类免疫的许多特征，但由于缺乏免疫试剂，同样未得到充分利用，因此开发交叉反应抗体来研究几种动物物种的免疫反应将影响对几种人类疾病的理解。

Integral Molecular proposes to generate a large panel of pan-reactive monoclonal antibodies (mAbs) against immune cell markers to be used in studies of immune function and responses in nine underrepresented mammalian models. Since certain mammalian models display many features of human immunity but are similarly underutilized due to lack of immunologic reagents, development of cross-reacting antibodies to study immune responses in several animal species will impact the understanding of several human diseases.