Administrative Core

行政核心

• 批准号: 10931064
• 负责人: Marina Y Konopleva
• 金额: $ 17.74万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10931064
• 关键词: Address; Administrator; Advocate; Award; Bioinformatics; Biometry; Cancer Center; Cancer Center Support Grant; Caring; Cell Therapy; Clinic; Clinical; Clinical Trials; Collaborations; Communication; Complex; Consultations; Data; Decision Making; Development; Doctor of Medicine; Electronic Mail; Eligibility Determination; Ensure; Fox Chase Cancer Center; Grant; Infrastructure; Institution; Interdisciplinary Study; Laboratories; Leadership; Minority; Monitor; National Cancer Institute; Organ; Outcome; Pathology; Patients; Policies; Preparation; Prognosis; Progress Reports; Protocols documentation; Publications; Quality Control; Regulation; Reporting; Reproduction spores; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Site; Stem cell transplant; Strategic Planning; Supervision; Texas; Tissues; Translational Research; United States National Institutes of Health; Universities; University of Texas M D Anderson Cancer Center; Woman; Work; career; data management; data sharing; design; experience; improved; interdisciplinary collaboration; lectures; leukemia; meetings; novel; programs; quality assurance; recruit; screening; success; symposium; transplantation therapy; web site

PROJECT SUMMARY (ADMINISTRATIVE CORE) The Administrative Core provides essential support to the MD Anderson Cancer Center and Temple/Fox Chase Cancer Center Leukemia SPORE PIs and investigators to maximize success. It is co-directed by Drs. Hagop Kantarjian and Jean-Pierre Issa, who co-chair the Executive Committee and provide overall supervision of five Projects, two additional Cores, Developmental Research (DRP) and Career Enhancement (CEP) Programs, and scientific direction of the SPORE. The Core co-Directors rely on the extensive broad-based scientific, research, and SPORE experience of the Internal and External Advisory Boards in critical decision- making. Success of the complex interdisciplinary research in the SPORE depends on integration of diverse leukemia research approaches. The Core will overcome barriers to interdisciplinary collaboration and data sharing and will ensure a unified translational research effort. The SPORE is founded on planning, integration, and translational research efforts supported by this Core. Its leadership and staff will be responsible for monitoring/planning scientific activities; providing scientific direction; ensuring emphasis on translational research; ensuring interdisciplinary and inter-SPORE integration with major leukemia programs within/outside MD Anderson and other broad translational research activities; and providing optimal administrative and fiscal management. Specific responsibilities of the Administrative Core are: Oversee and monitor all SPORE activities; promote integration and communication among the SPORE-related clinical programs; monitor the scientific integrity of all research projects, and grant awards; assure compliance with institutional, governmental, and National Cancer Institute regulations; oversee the fiscal and budgetary activities of the SPORE; coordinate data control quality assurance issues in conjunction with the Internal Advisory Board and the Biostatistics, Data Management, and Bioinformatics Core (Core 3); coordinate activities associated with clinical trials, including design of protocols, approval by regulatory bodies, implementation, and eligibility screening and assignment of patients to different studies; provide oversight and support for Core 3 and the Pathology and Tissue Core (Core 2); coordinate and manage meetings of the SPORE Executive Committee, the Internal and External Advisory Boards, monthly investigator meetings, quarterly research meetings, lectures, and symposia; administer the DRP and the CEP; coordinate interdisciplinary and inter-SPORE interactions and exchanges/meetings with other Leukemia SPORE programs and investigators, and other organ-site SPORE programs; administer the activities of the Patient Advocates; comply with, and improve policies addressing recruitment and retention of women and minorities; organize seminars to bring to MD Anderson consultants and speakers with expertise in various clinical and laboratory aspects of leukemia research; maintain a Leukemia SPORE website focused on issues in leukemia translational research.

项目概要（行政核心） 行政核心为MD安德森癌症中心和Temple/Fox提供必要的支持 大通癌症中心白血病孢子PI和研究人员，以最大限度地提高成功。它是由博士共同指导。 Hagop Kantarjian和Jean-Pierre Issa，他们共同主持执行委员会并提供全面监督 五个项目，两个额外的核心，发展研究（DRP）和职业提升（CEP） 计划和科学方向的孢子。核心共同主任依靠广泛的基础设施， 内部和外部咨询委员会在关键决策方面的科学、研究和SPORE经验- 制作。在SPORE复杂的跨学科研究的成功取决于不同的整合 白血病研究方法。核心将克服跨学科合作和数据的障碍 共享，并将确保统一的翻译研究工作。SPORE是建立在规划，整合， 以及该核心支持的转化研究工作。其领导层和工作人员将负责 监测/规划科学活动;提供科学指导;确保重视转化 研究;确保跨学科和跨孢子整合与主要白血病项目内/外 MD安德森和其他广泛的转化研究活动;并提供最佳的行政和财政 管理行政核心的具体职责是：监督和监测所有SPORE 活动;促进SPORE相关临床项目之间的整合和沟通;监测 所有研究项目的科学完整性，并授予奖项;确保遵守机构， 政府和国家癌症研究所的规定;监督财政和预算活动的 与内部咨询委员会一起协调数据控制质量保证问题， 生物统计学、数据管理和生物信息学核心（核心3）;协调与 临床试验，包括方案设计、监管机构批准、实施和合格性 筛选并将患者分配到不同的研究中;为核心3和 病理学和组织核心（核心2）;协调和管理SPORE执行委员会的会议， 内部和外部咨询委员会，每月研究者会议，季度研究会议， 讲座和研讨会;管理DRP和CEP;协调跨学科和跨SPORE 与其他白血病孢子项目和研究者的互动和交流/会议，以及其他 器官部位SPORE计划;管理患者倡导者的活动;遵守并改善 解决招聘和保留妇女和少数民族的政策;组织研讨会， 安德森顾问和发言人在白血病的各种临床和实验室方面的专业知识 研究;维护一个白血病孢子网站，专注于白血病转化研究的问题。