Regional Oncology Research Center (American Eurasian Cancer Alliance Supplement)

区域肿瘤学研究中心（美国欧亚癌症联盟增刊）

• 批准号: 10923392
• 负责人: WILLIAM George NELSON
• 金额: $ 48.1万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10923392
• 关键词: Acceleration; American; Area; Armenia; Asian; Azerbaijan; Belarus; COVID-19 pandemic; Central Asia; Country; Development; Education; Estonia; Europe; European; Financial Hardship; Government; Health; Human Resources; Kazakhstan; Kyrgyzstan; Latvia; Lithuania; Malignant Neoplasms; Moldova; NCI-Designated Cancer Center; Oncology; Policies; Population; Prevention; Prevention strategy; Public Health; Research; Research Institute; Research Training; Resource Allocation; Resources; Scientist; Tajikistan; Training and Education; Translating; Ukraine; United States; Uzbekistan; Work; anticancer research; cancer prevention; catalyst; interest; programs; success; treatment strategy; virtual

Project Summary/Abstract The American Eurasian Cancer Alliance (AECA) was formed in 2001, originally called American Russian Cancer Alliance (ARCA), representing a unique partnership of scientists and clinicians from Russian Federation and the United States. Based on the successes of ARCA and growing interest from Eastern European and Central Asian countries, the scope and depth of the alliance expanded to the Eurasian region encompassing research, research training, research to policy, and health diplomacy activities. The program was re-branded under the American Eurasian Cancer Alliance (AECA) in 2014 to represent the wider range of national participation, which encompasses the following regions: Russian Federation, Central Asia (Kazakhstan, Uzbekistan, Kyrgyzstan, Tajikistan), Central Europe (Ukraine, Moldova, Belarus), Baltics (Lithuania, Latvia, Estonia), and Caucasus (Armenia, Georgia, Azerbaijan). The Alliance aims to pool intellectual and scientific resources to further research and discovery in cancer prevention and treatment strategies. AECA’s programs focus on three main areas: 1. Strengthening Global Cancer Research 2. Promoting Research Training and Education 3. Translating Research into Policy and Programs AECA has formed partnerships with several countries in Eurasia which were formalized through Memoranda of Understanding between Ministries of Health for cooperation in cancer research, prevention, and control. Through continued engagement with high-level stakeholders, AECA facilitates allocation of resources by Eurasian governments and cancer research institutes for the mutual benefit of U.S. and local populations. This engagement results in reduced financial burden to NCI-Designated Cancer Centers, and other U.S.-based institutes to establish and implement their research programs. During the COVID pandemic, AECA has continued its worked uninterrupted, albeit through virtual channels, by continuing to facilitate research, conducting education and public health initiatives. AECA works with NCI personnel in this effort.

项目总结/摘要 美国欧亚癌症联盟（AECA）成立于2001年，最初名为美国俄罗斯癌症 联盟（ARCA），代表了来自俄罗斯联邦和美国的科学家和临床医生的独特伙伴关系。 美国的基于ARCA的成功以及东欧和中亚国家日益增长的兴趣， 国家，联盟的范围和深度扩大到欧亚地区，包括研究， 研究培训、政策研究和卫生外交活动。 该计划于2014年在美国欧亚癌症联盟（AECA）下重新命名，以代表 更广泛的国家参与，包括以下地区：俄罗斯联邦、 亚洲（哈萨克斯坦、乌兹别克斯坦、吉尔吉斯斯坦、塔吉克斯坦）、中欧（乌克兰、摩尔多瓦、白俄罗斯）、波罗的海国家 （立陶宛、拉脱维亚、爱沙尼亚）和高加索地区（亚美尼亚、格鲁吉亚、阿塞拜疆）。该联盟旨在汇集知识分子， 和科学资源，以进一步研究和发现癌症预防和治疗策略。AECA的 方案侧重于三个主要领域： 1.加强全球癌症研究 2.促进研究培训和教育 3.将研究转化为政策和计划 AECA与欧亚大陆的几个国家建立了伙伴关系，这些伙伴关系是通过1999年的《联合国宪章》正式确定的。 卫生部之间关于在癌症研究、预防和控制方面合作的谅解。通过 通过与高级别利益相关者的持续接触，AECA促进了欧亚地区的资源分配， 政府和癌症研究机构为美国和当地居民的共同利益。这 参与减少了NCI指定癌症中心和其他美国-基于 研究机构建立和实施其研究计划。在COVID大流行期间，AECA继续 它的工作不间断，虽然是通过虚拟渠道，继续促进研究， 教育和公共卫生举措。AECA在这方面与NCI人员合作。

项目成果

Effect of delays in initiation of adjuvant endocrine therapy on survival among women with breast cancer.

• DOI: 10.1007/s10549-020-05910-0
• 发表时间: 2020-12
• 期刊: Breast cancer research and treatment
• 影响因子: 3.8
• 作者: Lee KT;Jacobs L;Walsh EM;Stearns V;Segal JB
• 通讯作者: Segal JB

STINGing the immune system: lessons learned through a model of G34-mutant pediatric high-grade glioma.

• DOI: 10.1172/jci164420
• 发表时间: 2022-11-15
• 期刊: JOURNAL OF CLINICAL INVESTIGATION
• 影响因子: 15.9
• 作者: Hall, Connor P.;Cronk, James C.;Rubens, Jeffrey A.
• 通讯作者: Rubens, Jeffrey A.

Polyamines in cancer: integrating organismal metabolism and antitumour immunity.

• DOI: 10.1038/s41568-022-00473-2
• 发表时间: 2022-08
• 期刊: Nature reviews. Cancer

Association of B7-H3 expression with racial ancestry, immune cell density, and androgen receptor activation in prostate cancer.

• DOI: 10.1002/cncr.34190
• 发表时间: 2022-06-15
• 期刊: Cancer
• 影响因子: 6.2

Association between Trichomonas vaginalis and prostate cancer mortality.

• DOI: 10.1002/ijc.31885
• 发表时间: 2019-05-15
• 期刊: International journal of cancer
• 影响因子: 6.4
• 作者: Tsang SH;Peisch SF;Rowan B;Markt SC;Gonzalez-Feliciano AG;Sutcliffe S;Platz EA;Mucci LA;Ebot EM
• 通讯作者: Ebot EM