Phase III Development of a Valid, Reliable, Clinically Feasible Measure of Transactional Success in Aphasic Conversation: Modernizing Methods of Acquisition and Analysis of Discourse Data

失语对话中交易成功的有效、可靠、临床可行的衡量标准的第三阶段开发：话语数据采集和分析的现代化方法

• 批准号: 10617305
• 负责人: Jacquie Kurland
• 金额: $ 19.94万
• 依托单位: UNIVERSITY OF MASSACHUSETTS AMHERST
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10617305
• 关键词: Address; Affect; American; Aphasia; Area; Assessment tool; Characteristics; Chronic; Clinical; Code; Collection; Communication; Computer software; Consumption; Data; Data Analyses; Data Collection; Databases; Development; Discourse analysis; Disease; Elderly; Elements; Expressive Aphasia; Factor Analysis; Familiarity; Genetic Transcription; Goals; Impairment; Intervention; Joints; Language; Language Disorders; Left; Life; Linguistics; Manuals; Measurement; Measures; Mediation; Methods; Modeling; National Institute on Deafness and Other Communication Disorders; Natural Language Processing; Nature; Non-aphasic; Online Systems; Outcome; Outcome Measure; Performance; Persons; Phase; Psychometrics; Pythons; Reporting; Research; Research Personnel; Resources; Sampling; Severities; Social isolation; Source; Speech; Speech Therapy; Stimulus; Strategic Planning; Technology; Testing; Text; Time; Transact; Treatment outcome; Validation; Videoconferencing; Voice; Workload; automated analysis; clinical application; clinical practice; cohort; design; disability; efficacy research; expectation; experience; improved; innovation; interest; language impairment; language outcome; multimodality; novel; open source tool; programs; psychosocial; remote delivery; skills; stem; stroke survivor; success; theories; tool; treatment response

SUMMARY Models for assessing and treating aphasia, a language disorder affecting at least 2.5 million Americans, have gradually moved from an impairment-based to a participation-based framework. However, there exist no valid, reliable, clinically practical tools for directly measuring gains in conversation, the most frequent communicative activity of daily life in older adults. The long-range goal of the proposed study is to provide a theoretically grounded, practical, automated tool for clinicians and clinical researchers to assess changes in transactional success in conversation without transcribing and analyzing aphasic discourse, a time- and resource-intensive skill that hinders the inclusion of conversational discourse in treatment outcomes. We propose to fill this gap with the recently piloted Brief Assessment of Transactional Success in conversation (BATS). After watching and/or listening to short (2.5 minute) BATS video/audio stimuli, people with aphasia (PWA) retell the story in a monologic discourse task and then engage with a conversation partner who is naïve to the story, who then retell the story. The objectives of the proposed study are twofold: Aim 1 will demonstrate the reliability of the BATS and its validity in assessing transactional success. Reliability coefficients will be calculated for alternate forms of the video/audio stimuli as assessed by core lexicons, main concepts and comprehensiveness ratings. The magnitude of multiple potential sources of measurement error will be estimated to identify optimal data collection conditions (e.g., conversation partner familiarity). Evidence of converging and discriminant validation will evaluate the degree to which the BATS measures constructs such as joint action, total communication, and context, the three core elements that characterize the situated language use model of communication, and that enable PWA to communicate better than they talk. Aim 2 will advance automated methods of studying discourse in aphasia. Text analysis tools from open-source natural language processing platforms will interface with Python programs to assess core lexicons and topic similarity in conversation partner story retells. Pilot data suggests that use of automated methods for assessing micro- and macrolinguistic features of discourse to reveal transactional success in conversation in aphasia is feasible. This research is innovative because it applies 21st century videoconferencing technology to deliver a novel tool for assessing transactional success in conversation, while developing an automated software application to make the tool accessible to clinicians and clinical researchers who serve PWA, even in remote areas. The contribution is significant in that it will overcome a major obstacle in measuring real-world functional response to therapy in aphasia. Incorporating the three levels of BATS discourse (PWA story retells, dyadic conversations, and conversation partner retells) into AphasiaBank will create a rich, shared online database for studying how PWA succeed in co-constructing meaning in conversation. This project reflects current priorities in Areas 3 and 4 in the NIDCD strategic plan for Voice, Speech, and Language Research.

总结 失语症是一种影响至少250万美国人的语言障碍， 逐步从基于损伤的框架转向基于参与的框架。然而，没有有效的， 可靠的，临床实用的工具，直接测量收益的谈话，最频繁的沟通 老年人的日常生活活动。这项研究的长期目标是提供一个理论上的 为临床医生和临床研究人员提供了一个接地，实用，自动化的工具，以评估交易中的变化 成功的谈话没有转录和分析失语症的话语，一个时间和资源密集型 阻碍治疗结果中包含对话的技能。我们建议填补这一空白 最近试行的对话中的transmittance成功的简要评估（BATS）。看完 和/或听短（2.5分钟）的BATS视频/音频刺激，失语症（PWA）的人复述故事， 独白话语任务，然后与一个对故事一无所知的对话伙伴进行交谈， 复述这个故事。拟议研究的目标有两个：目标1将证明 BATS及其评估交易成功的有效性。将计算可靠性系数， 通过核心词汇、主要概念和 综合评分。多个潜在的测量误差源的大小将是 估计以识别最佳数据收集条件（例如，会话伙伴熟悉度）。的证据 收敛验证和判别验证将评估BATS措施在多大程度上构建了 作为联合行动，全面沟通，和背景，三个核心要素，特点的情况下 语言使用交流模型，这使得PWA能够比他们说话更好地交流。目标2将 研究失语症的自动化方法。来自开源natural的文本分析工具 语言处理平台将与Python程序接口，以评估核心词汇和主题相似性 在谈话中，伙伴复述故事。试点数据表明，使用自动化方法评估微观 和语篇的宏观语言学特征来揭示失语症患者会话中的交易成功是可行的。 这项研究是创新的，因为它应用了21世纪的视频会议技术，以提供一个新的 在开发自动化软件应用程序时，用于评估对话中的事务成功的工具 使为PWA服务的临床医生和临床研究人员能够使用该工具，即使是在偏远地区。的 贡献是显着的，因为它将克服一个主要障碍，在衡量现实世界的功能 对失语症治疗的反应。对BATS语篇的三个层次（PWA故事复述、二元结构、 会话，和会话伙伴复述）到失语症银行将创建一个丰富的，共享的在线数据库， 研究PWA如何成功地在会话中共同构建意义。该项目反映了当前的优先事项 在NIDCD语音，言语和语言研究战略计划的领域3和4。