Medical Scientist Training Program

项目摘要 科罗拉多大学MD/PhD项目（CU-MSTP）成立于1983年，成功培养了 263名双学位学生，以扩大医生科学家的劳动力。CU-MSTP一直得到资助， 自1992年以来，我们的计划最近从75名学生增加到目前的86名学生。 我们的计划使命是培养双学位学生的多元化干部，成为优秀的医生- 生物医学研究的科学家和未来的领导者。为了完成这一使命，我们选择学生从 增加国家申请人库（从2017年的386人增加到2021年的567人），寻找那些 研究，学术和领导成就是典范。CU-MSTP招聘10-11名不同的申请人 每年从全国各地，是两个服务于九个西部山区国家的计划之一。CU-MSTP 使用全面的审查流程来确定申请人的经验，属性和指标，项目可能 在我们的项目和作为医生科学家的成功。我们目前的86名学生名册（48%女性; 16% URM， 8%的残疾人，15%的第一代大学生，25%的弱势群体）来自全国各地，来自各种 教育背景，并具有重要的研究经验和出版物。最近的几 体制改革改善了CU-MSTP学生的培训环境。我们的MSTP学生受益于 2021年实施的创新的新医学院“Trek”课程， 纵向综合临床培训。由此产生的新MSTP“返回”课程将严格的 以高度整合、灵活和个性化的方式进行前沿医学培训的研究培训， 保持先前CU-MSTP培训计划的优势，并保持约8年时间轴完成 两个度。对于论文研究，我们的学生选择从各种各样的领域与MSTP教师在15 三个校区的研究生培训计划（安舒茨医学校区，国家犹太健康， 科罗拉多大学博尔德分校）。参与CU-MSTP的教师有一个合并的年度补助金收入 ~ 6000万美元。为了提高学生的成功，我们在整个培训期间提供职业指导， 我们努力工作，把我们的毕业生在精英居住和奖学金。我们的学生在以下方面表现出色： 预测医生科学家职业成功的指标，包括发表有影响力的同行评审 手稿，获得早期的研究资金，并在竞争激烈，以研究为重点的住院医师匹配。CU 医学院为CU-MSTP提供强有力的支持，2017-2021年总支持额为1697万美元 五年周期。不断发展的安舒茨医学校园提供最先进的教育，研究和临床 设施，并享有与最近的主要校园举措，包括新的中心， Health AI，RNA Biosciences Initiative和生物医学信息学系。总之，连续 完善项目，扩大申请人库，招生质量和培训教师，学生 成果、机构支持、研究资金和环境证明我们要求每年提供21个培训名额是合理的。

PROJECT SUMMARY The University of Colorado MD/PhD Program (CU-MSTP) was established in 1983 and has successfully trained 263 dual-degree students to expand the physician-scientist workforce. CU-MSTP has been continuously funded by NIGMS since 1992, with our program recently growing from ~ 75 students to a current total of 86 students. Our Program Mission is to train a diverse cadre of dual-degree students to become outstanding physician- scientists and future leaders in biomedical research. To accomplish this mission, we select students from an increasing national applicant pool (from 386 in 2017 to 567 in 2021), seeking out those candidates whose record of research, academic, and leadership achievements are exemplary. CU-MSTP recruits 10-11 diverse applicants per year from across the nation, being one of two programs serving the nine Mountain West states. CU-MSTP uses a holistic review process to identify applicants with experiences, attributes, and metrics that project likely success in our program and as physician scientists. Our current roster of 86 students (48% female; 16% URM, 8% disabled, 15% 1st generation college, and 25% disadvantaged) come from across the nation, from a variety of educational backgrounds, and with significant prior research experience and publications. Several recent institutional changes enhance the training environment for CU-MSTP students. Our MSTP students benefit from an innovative new medical school “Trek” curriculum implemented in 2021 that incorporates novel early longitudinal integrated clinical training. The resulting new MSTP “Switchback” curriculum connects rigorous research training with cutting-edge medical training in a highly integrated, flexible, and individualized manner, maintaining the strengths of the prior CU-MSTP training plan and keeping the ~8-year timeline for completion of both degrees. For thesis research, our students choose from a wide variety of fields with MSTP faculty in 15 graduate training programs across three campuses (Anschutz Medical Campus, National Jewish Health, and the University of Colorado-Boulder). Participating CU-MSTP faculty have a combined annual grant income of ~$60M. To enhance the success of our students, we provide career guidance throughout the training period, and we work diligently to place our graduates in elite residencies and fellowships. Our students have excelled in metrics that predict career success as physician scientists, including publishing impactful peer-reviewed manuscripts, obtaining early research funding, and matching in competitive, research-focused residencies. CU School of Medicine provides strong support to CU-MSTP, with a total of $16.97M total support in the 2017-2021 five-year cycle. The growing Anschutz Medical Campus provides state-of-the-art education, research and clinical facilities, and enjoys significant momentum with recent major campus initiatives including the new Center for Health AI, RNA Biosciences Initiative, and Department of Biomedical Informatics. In sum, the continuous improvement of the Program, enlarging applicant pool, quality of recruited students and training faculty, student outcomes, institutional support, research funding and environment justifies our request for 21 training slots/year.