Medical Scientist Training Program

项目总结 科罗拉多大学医学博士项目(CU-MSTP)成立于1983年，已成功培训 263名双学位学生，以扩大医生-科学家队伍。CU-MSTP一直得到持续资助 自1992年以来，我们的项目从大约75名学生增加到目前的86名学生。 我们的项目使命是培养一支多元化的双学位学生干部队伍，成为优秀的医生- 科学家和未来生物医学研究的领导者。为了完成这一使命，我们从 增加全国申请者人数(从2017年的386人增加到2021年的567人)，寻找那些记录 研究、学术和领导成就堪称典范。CU-MSTP招聘10-11名不同的申请者 每年来自全国各地，是服务于西部山区九个州的两个项目之一。CU-MSTP 使用全面的审查流程来确定申请者的经验、属性和指标 在我们的项目中和作为内科科学家取得成功。我们目前的花名册上有86名学生(48%是女性，16%是URM， 8%的残疾人，15%的第一代大学，25%的弱势群体)来自全国各地，来自不同的种族 教育背景，并具有丰富的研究经验和出版过的出版物。最近的几个 制度变革改善了CU-MSTP学生的培训环境。我们的MSTP学生受益于 2021年实施的创新的医学院新课程《Trek》，融合了早期的小说 纵向综合临床培训。由此产生的新的MSTP“折返”课程将严格 以高度集成、灵活和个性化的方式将研究培训与尖端医学培训结合在一起， 保持先前CU-MSTP培训计划的优势，并保持完成以下目标的~8年时间表 两个学位。对于论文研究，我们的学生在MSTP教员的15个领域中进行了广泛的选择 三个校区的研究生培训计划(安舒茨医学院、国家犹太人健康中心和 科罗拉多大学博尔德分校)。参加CU-MSTP的教职员工每年的总助学金收入为 ~6000万美元。为了提高学生的成就率，我们在整个培训期间提供职业指导， 我们努力将我们的毕业生安排在精英住校和奖学金项目中。我们的学生在 作为内科科学家预测职业成功的指标，包括发表有影响力的同行评议 手稿，获得早期研究资金，以及在竞争激烈的、专注于研究的住院医生中进行匹配。铜 医学院为CU-MSTP提供了大力支持，2017-2021年总共提供了1697万美元的支持 五年为一个周期。不断发展的安舒茨医学院提供最先进的教育、研究和临床 设施，并享受着最近的主要校园倡议的显著势头，包括新的 健康人工智能、核糖核酸生物科学倡议和生物医学信息学系。总而言之，连续的 改进计划，扩大申请者队伍，提高招生质量，培养师资和学生 结果、机构支持、研究资金和环境使我们有理由要求每年提供21个培训名额。

PROJECT SUMMARY The University of Colorado MD/PhD Program (CU-MSTP) was established in 1983 and has successfully trained 263 dual-degree students to expand the physician-scientist workforce. CU-MSTP has been continuously funded by NIGMS since 1992, with our program recently growing from ~ 75 students to a current total of 86 students. Our Program Mission is to train a diverse cadre of dual-degree students to become outstanding physician- scientists and future leaders in biomedical research. To accomplish this mission, we select students from an increasing national applicant pool (from 386 in 2017 to 567 in 2021), seeking out those candidates whose record of research, academic, and leadership achievements are exemplary. CU-MSTP recruits 10-11 diverse applicants per year from across the nation, being one of two programs serving the nine Mountain West states. CU-MSTP uses a holistic review process to identify applicants with experiences, attributes, and metrics that project likely success in our program and as physician scientists. Our current roster of 86 students (48% female; 16% URM, 8% disabled, 15% 1st generation college, and 25% disadvantaged) come from across the nation, from a variety of educational backgrounds, and with significant prior research experience and publications. Several recent institutional changes enhance the training environment for CU-MSTP students. Our MSTP students benefit from an innovative new medical school “Trek” curriculum implemented in 2021 that incorporates novel early longitudinal integrated clinical training. The resulting new MSTP “Switchback” curriculum connects rigorous research training with cutting-edge medical training in a highly integrated, flexible, and individualized manner, maintaining the strengths of the prior CU-MSTP training plan and keeping the ~8-year timeline for completion of both degrees. For thesis research, our students choose from a wide variety of fields with MSTP faculty in 15 graduate training programs across three campuses (Anschutz Medical Campus, National Jewish Health, and the University of Colorado-Boulder). Participating CU-MSTP faculty have a combined annual grant income of ~$60M. To enhance the success of our students, we provide career guidance throughout the training period, and we work diligently to place our graduates in elite residencies and fellowships. Our students have excelled in metrics that predict career success as physician scientists, including publishing impactful peer-reviewed manuscripts, obtaining early research funding, and matching in competitive, research-focused residencies. CU School of Medicine provides strong support to CU-MSTP, with a total of $16.97M total support in the 2017-2021 five-year cycle. The growing Anschutz Medical Campus provides state-of-the-art education, research and clinical facilities, and enjoys significant momentum with recent major campus initiatives including the new Center for Health AI, RNA Biosciences Initiative, and Department of Biomedical Informatics. In sum, the continuous improvement of the Program, enlarging applicant pool, quality of recruited students and training faculty, student outcomes, institutional support, research funding and environment justifies our request for 21 training slots/year.