An Interdisciplinary Training Program to Transform Graduate Education In Genetics and Genomics

项目总结 遗传学是生物医学研究和临床实践的核心基础学科。我们的任务是训练 21世纪的遗传学家。为了实现这一目标，我们设计并实现了一个跨学科的 旨在改变明尼苏达大学遗传学和基因组学研究生教育的培训计划。我们的 具体目标是：(I)为学生提供严格和定量的基础和状态培训- 遗传学、基因组学和计算生物学的最新进展；(Ii)利用许多协作 我们机构的研究和教育优势，以提供以学生为中心的跨学科新毕业生 超越部门和学院界限的培训机会；以及(Iii)产生多样化的 一群训练有素的科学家，能够将他们广泛的技能和对终身学习的渴望整合到 他们的工作涉及生物医学劳动力的多种职业。该计划将使学员能够 在学术界、生物技术、政府、医疗保健或教育领域追求许多有影响力的职业机会 由遗传学和基因组学的最新进展创造的，包括正在经历的领域的职业 快速变化，以及在目前不存在或刚刚起步的领域的职业。为表彰 事实是，明天的遗传学家必须拥有定量的敏锐，我们不仅开发出了新的 课程强调生物信息学和计算方法，但我们也将这些整合到我们的 通过根据内部和外部评估对研究生课程进行重大重新设计的培训方案 外部审查小组。从某种意义上说，遗传学和基因组学是超越和统一的基础领域 生物科学中的多个学科，因为生物区别于无生命物体的是什么 所有生物体内都有构建它们的分子蓝图，基因组。一个有影响力的 这个学术和研究培训项目的一个方面是它寻求超越传统的部门 通过将生物医学科学中来自多个学科的研究人员聚集在一起来实现边界 在他们的研究中利用遗传和基因组分析。通过这样做，这个培训计划试图促进 跨学科研究，培育协作团队科学，实施以学生为中心的个性化 教育和职业发展计划。我们的培训计划包括50个高生产率和 来自明尼苏达大学五个学院的十个系的合作教员。我们正在寻找 为6名博士生提供资助，从第二年开始，每人为期两年 第一年由机构基金提供。除了他们的论文研究外，学员还将参与 专业发展方案，旨在促进他们过渡到 与生物医学科学相关的职业。

PROJECT SUMMARY Genetics is a foundational discipline central to biomedical research and clinical practice. Our mission is to train geneticists for the 21st century. To achieve this goal, we have designed and implemented an interdisciplinary training program to transform graduate education in genetics and genomics at the University of Minnesota. Our Specific Aims are: (i) to provide students with rigorous and quantitative training in the fundamentals and state- of-the-art advances in genetics, genomics, and computational biology; (ii) to leverage the many collaborative research and educational strengths of our institution to provide new interdisciplinary student-centered graduate training opportunities that transcend departmental and collegiate boundaries; and (iii) to generate a diverse cohort of well-trained scientists able to integrate their broad skillset and their hunger for lifelong learning into their work across a multitude of careers in the biomedical workforce. This program will enable trainees to pursue many impactful career opportunities in academia, biotechnology, government, health care, or education created by recent advancements in genetics and genomics, including careers in fields that are undergoing rapid change, as well as careers in areas that do not presently exist or that are nascent. In recognition of the fact that the geneticists of tomorrow must possess quantitative acumen, we have not only developed new courses emphasizing bioinformatics and computational approaches, but we have also integrated these into our training program through a major redesign of the graduate curriculum pursuant to evaluation by internal and external review panels. In a sense, genetics and genomics are foundational fields that transcend and unify multiple disciplines within the biological sciences because what sets living things apart from inanimate objects is that all living things possess within them molecular blueprints for their construction, genomes. An impactful aspect of this academic and research training program is that it seeks to transcend traditional departmental boundaries by bringing together researchers from multiple disciplines within the biomedical sciences who utilize genetic and genomic analyses in their research. In so doing, this training program seeks to promote interdisciplinary research, foster collaborative team science, and implement individualized student-centered educational and career development programs. Our training program includes 50 highly productive and collaborative faculty from ten departments across five colleges at the University of Minnesota. We are seeking support for six PhD trainees for two years each beginning in year two of their academic program, with funding for year one provided by institutional funds. In addition to their thesis research, trainees will participate in professional development programs aimed at promoting their transition into and long-term success in biomedical science-related careers.