Training Program in Cell and Molecular Biology

项目概要/摘要 此应用程序是唯一的培训补助金的第五个竞争性更新支持整合分子 和贝勒医学院生物医学科学研究生课程（IMBS）。IMBS计划是 资助的承诺，以卓越的研究，与严格的指导方针，为学生和教师 参与该计划。该计划目前涉及来自多个机构的106名参与教师 德州医疗中心这种既有资深调查员又有新招募的年轻人的动态组合 具有不同研究兴趣的教师允许IMBS学生与世界一流的科学家一起训练，并从 一系列令人兴奋的研究可能性在24年的资助期间，250名学生进入了 该计划，目前有80名学生注册。在离开方案的170名受训人员中， 他们的博士学位17人获得硕士学位，31人退学或转学。我们一直吸引高 有能力的学生使用积极的招聘策略计划。在此期间增加机构支助 在过去的四年里，资助期使我们能够将入学人数从9人增加到16人 每一年。我们继续强调严格的研究生教育计划，结合密集， 个性化指导贯穿IMBS研究生培训的各个阶段。IMBS的研究生产力 从学生撰写的出版物的数量和质量来衡量，学生一直是例外。 2009年至2013年期间，从该计划毕业的学生拥有非常强大的出版物 记录这44名学生平均发表了3.4篇论文，其中1.4篇是他们的论文研究成果， 是第一作者论文，平均影响因子为8.8。另一位值得注意的是 在上一个资助期内，我们在招聘和留住人才方面取得了持续的成功， 代表性不足的少数民族（URM）的学生，与11 URM学生（14%）目前在该计划注册。在 此外，我们目前的URM IMBS学生包括学院中的一些顶尖学生， 学术成就。在上一个培训期间，10个博士前职位通过这一资助 奖我们要求在目前的续约中增加到12个供资职位， 招聘和培训在学术界、工业界担任科学领导职务的顶尖学生的良好记录 和政府。我们计划维持一个约80名学生的注册学生团体，这是科学研究的最佳规模。 项目教师的互动和指导。

Project Summary/Abstract This application is the fifth competing renewal of the sole training grant supporting the Integrative Molecular and Biomedical Sciences Graduate Program (IMBS) at Baylor College of Medicine. The IMBS Program was funded on a commitment to excellence in research, with strict guidelines for both student and faculty participation in the program. The Program currently involves 106 participating faculty from multiple institutions throughout the Texas Medical Center. This dynamic mix of established investigators and newly recruited young faculty with diverse research interests allows IMBS students to train with world-class scientists and select from a wide spectrum of exciting research possibilities. During the 24 years of funding, 250 students have entered the program, with 80 students currently enrolled. Of the 170 trainees who have left the Program, 122 received their Ph.D., 17 received Master's degrees, and 31 withdrew or transferred. We have consistently attracted high caliber students to the Program using active recruitment strategies. Increased institutional support during this funding period has allowed us to increase the entering class size over the past four years from 9 to 16 students per year. We continue to emphasize a rigorous graduate education program, combined with intensive, personalized mentoring throughout all stages of IMBS graduate training. The research productivity of IMBS students has been exceptional, as measured by both the number and quality of student-authored publications. Students who graduated from the Program, between 2009 and 2013, have extremely strong publication records. These 44 students published, on average, 3.4 papers resulting from their thesis research, 1.4 of which were first author papers, with an average impact factor of 8.8 per publication. An additional notable achievement during the last funding period has been our continued success in both recruiting, and retaining, underrepresented minority (URM) students, with 11 URM students (14%) currently enrolled in the program. In addition, our current URM IMBS students include some of the top students in the College with regard to academic achievements. During the previous training period, 10 predoctoral positions were funded through this award. We are requesting an increase to 12 funded positions in the current renewal, based on our established track record of recruiting and training top students who take science leadership positions in academia, industry and government. We plan to maintain an enrolled student body of ~80 students, an optimal size for scientific interactions and mentoring by Program faculty.