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Admin-Core

管理核心

基本信息

批准号：
10863392
负责人：
MICHAEL OLIVIER
金额：
$ 10万
依托单位：
WAKE FOREST UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-01 至 2026-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10863392
关键词：
Acute Acute Pain Blood specimen California Charge Clinical Clinical Data Clinical assessments Cohort Studies Collaborations Communication Data Data Set Development Dimensions Doctor of Philosophy Ensure Epigenetic Process Event Funding Generations Genotype Goals Health Sciences Individual Individual Adjustment Institution Leadership Mediating Monitor Multiomic Data Operative Surgical Procedures Pain Participant Proteomics Psychosocial Assessment and Care RNA Research Personnel Sampling Sensory System Technical Expertise Testing United States National Institutes of Health Universities Work biomarker identification biomarker signature chronic pain clinical center clinical research site data exchange data integration data resource experience extracellular forest individual patient large scale data lipidomics medical schools metabolomics monocyte multiple omics musculoskeletal injury neuroimaging operation pain chronification performance site precision medicine predictive signature programs resilience success timeline

项目摘要

SUMMARY The Omics Data Generation Center (ODGC) proposed in this application is a collaborative effort of three academic institutions with complementary technical expertise, experience in large-scale data generation projects, and established collaborations and interactions: Wake Forest University Health Sciences (WFUHS) in Winston-Salem, NC, Duke University School of Medicine (Duke) in Durham, NC, and the University of California (UCD) in Davis, CA. The Administrative Core of the ODGC will coordinate the effective operation of the entire ODGC across the three performance sites, facilitate interaction and communication between all Cores and Components of the ODGC, and monitor progress of the data generation and analysis. Furthermore, the Administrative Core will interact with the Multisite Clinical Centers, the Data Integration and Resource Center, and another ODGC (if another is funded) of the A2CPS Consortium to coordinate sample and data transfer, and maintain communications to coordinate all activities with NIH and the A2CPS Consortium. Specifically, it is the goal of the Administrative Core to: a) Coordinate, monitor, and safeguard the entire operations of the ODGC, from sample requests to final omics data transfer, and to ensure that all data collected can be seamlessly integrated and analyzed. b) Coordinate interactions with the entire A2CPS Consortium, its individual Centers, and NIH to ensure that the Consortium accomplishes the overall goals of the A2CPS effort. To accomplish these goals, the Administrative Core of the ODGC is creating four Teams that will operate across the individual Cores and Components of the ODGC: 1. The Leadership Team, (Tim Howard, PhD, Carl Langefeld, PhD, Michael Olivier, PhD, Oliver Fiehn, PhD). 2. The Pain Expert Team (James Eisenach, MD, Wolfgang Liedtke, MD, PhD, Yusuke Shiozawa, MD, PhD, Roy Strowd, MD). 3. The Sample Coordination Team (Nichole Allred, PhD, Laura Cox, PhD, Hector Guillen, PhD). 4. The Data QC and Analysis Team (Carl Langefeld, PhD, Ellen Quillen, PhD). All Teams of the Administrative Core of the ODGC will be supported by an experienced administrative support team at the WFUHS Center for Precision Medicine, and all efforts will be coordinated by the ODGC Program. Coordinator, Claudia Olivier, PhD. The Administrative Core will work closely with the A2CPS Consortium to ensure the successful completion of the ODGC goals.

总结