OCCUPATIONAL CANCER SURVEILLANCE: NEW APPROACHES

职业癌症监测：新方法

基本信息

批准号：
3420268
负责人：
G MARIE SWANSON
金额：
$ 7.94万
依托单位：
MICHIGAN STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1990
资助国家：
美国
起止时间：
1990-02-01 至 1994-09-29
项目状态：
已结题

项目摘要

During the first 6 years of this study, telephone interviews have been completed with over 17,000 subjects. Lifetime cigarette smoking histories and occupational histories provide data for assessing workplace risk for eleven cancer sites: lung and bronchus, urinary bladder, colon, rectum, stomach, esophagus, mesothelioma, eye, salivary glands, liver, and melanoma of the skin. A primary objective of this study is to determine occupational cancer risks among blacks and women. Little is known about such risks among women or blacks because nearly all research in this area includes only white men. Other specific aims of this study include investigation of occupational cancer risks among persons who never smoked cigarettes; assessing whether cancer occurs at a younger age than expected in conjunction with occupational risks and determination of occupational cancer risks wig& predominant local industries, such as automobile manufacturing, construction, primary ferrous metals manufacturing, machinery manufacturing, and food processing. Detailed work histories, tobacco use histories, health history, and demographics have been obtained by telephone interview. By the end of the current grant period interviews will be completed with 14,900 cancer cases and 3,366 population referents. Cancer cases were selected from a population-based cancer registry; population referents were selected by random digit dialing. The proposed renewal is for completion of data analysis. The long-term objectives of this study are to develop new hypotheses about occupational cancer risks, provide evidence to support previous suggestions of occupational cancer risk, and ultimately to prevent cancers resulting from workplace exposures.

在本研究的前6年中，电话采访有由17,000多名受试者完成。终生吸烟历史和职业历史提供了评估工作场所的数据 11个癌症部位的风险：肺和支气管，泌尿膀胱，结肠，直肠，胃，食道，间皮瘤，眼睛，唾液腺，肝脏，肝脏，和皮肤黑色素瘤。这项研究的主要目的是确定黑人和妇女的职业癌风险。几乎没有关于妇女或黑人中这种风险的了解，因为几乎所有研究在这个地区，只有白人。本研究的其他具体目标包括调查对职业癌的风险的调查从来没有抽烟；评估癌症是否在年轻时发生与职业风险和确定职业癌症风险假发和主要的地方行业，例如汽车制造，建筑，主要亚铁金属制造，机械制造和食品加工。详细的工作历史，烟草使用历史，健康史和人口统计学已通过电话采访获得。到结束当前的赠款期访谈将通过14,900癌完成案件和3,366个人口参考。从A中选择了癌症基于人群的癌症登记；人口参考人是由随机数字拨号。拟议的续约是为了完成数据分析。这这项研究的长期目标是提出有关的新假设职业癌症风险，提供证据以支持以前职业癌风险的建议，并最终阻止工作场所暴露导致的癌症。