Novel targeted degradable multifunctional poly(vinyl-co-ester) nanoparticles for Alzheimer’s disease applications

用于阿尔茨海默病应用的新型靶向可降解多功能聚（乙烯酯）纳米颗粒

• 批准号: nhmrc : GNT1109945
• 负责人: Dr Kristian Kempe
• 金额: $ 60.19万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Boosting Dementia Research Initiative
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-targeted-degradable-disease-applications/1346704
• 关键词: Novel; targeted; degradable; multifunctional; poly

Novel biodegradable polymeric nanoparticles for efficient and targeted delivery of Alzheimer related agents to the brain will be developed. The nanocarriers will be fabricated from biocompatible multifunctional compounds and possess the capability to co-deliver diagnostic and therapeutic agents across the blood-brain barrier. These systems are expected to become a new efficient class of brain delivery systems.

新型生物可降解聚合物纳米粒子的有效和有针对性的交付阿尔茨海默氏症相关的药物到大脑将被开发。纳米载体将由生物相容性多功能化合物制成，并具有跨血脑屏障共同递送诊断和治疗剂的能力。这些系统有望成为一种新型高效的脑传递系统。