Expanding the toolbox of synthetic stealth polymers

扩展合成隐形聚合物的工具箱

• 批准号: FT190100572
• 负责人: Dr Kristian Kempe
• 金额: $ 54.65万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-04-01 至 2024-04-14
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT190100572
• 关键词: Expanding; toolbox; synthetic; stealth; polymers

This project aims to develop a new generation of synthetic and biomimetic pseudo peptide polymers with advanced biomedical properties. The polymers will be used for the fabrication of a range of nanoparticles, which will allow to study the effect of architecture, composition and surface functionalisation on their behaviour in a biological environment. Carefully conducted structure-physicochemical property relationship and bio-nano interaction studies will generate new knowledge in the area of stealth and protein repellent nanomaterials. The intended outcome of the project is the generation of a platform of bioinert materials that could potentially find applications as building blocks in next generation nanomedicines and medical devices.

该项目旨在开发新一代具有先进生物医学特性的合成和仿生假肽聚合物。这些聚合物将用于制造一系列纳米颗粒，这将允许研究结构，组成和表面功能化对其在生物环境中行为的影响。精心进行的结构-物理化学性质关系和生物纳米相互作用的研究将产生新的知识领域的隐形和蛋白质排斥纳米材料。该项目的预期成果是产生一个生物惰性材料平台，该平台可能会作为下一代纳米医学和医疗设备的构建模块得到应用。